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The map label for this gene is trkA [H]

Identifier: 188584896

GI number: 188584896

Start: 267999

End: 268664

Strand: Direct

Name: trkA [H]

Synonym: Nther_0254

Alternate gene names: 188584896

Gene position: 267999-268664 (Clockwise)

Preceding gene: 188584895

Following gene: 188584897

Centisome position: 8.47

GC content: 32.58

Gene sequence:

>666_bases
ATGAAGATTATTTTAGTTGGTGGAGGAAATAAAGTACACTATCTTGCTAAAACATTTATTTCTCAAGGGCATGAGTTAAC
CTTGATAAATAATGAGAAAGAATACTGTCGAGATCTAGCCAAAAGGTTTGATGTAAATATTGTATACGGTGATGGTACAA
AACCCAATATATTAGAAGATGCAGAAGTTTTAACTGCCGACTTAGTAATGGCTGTTACCCCAAAAGATCCAGATAACTTA
GTAATATGTCAGTTAGCAAATAAAGTTTACGAAGTAGATAAAACATTTGCAATTGTTAACGATCCAGATAATATCGAAAT
TTTTAAAAAGCTTGGTGTAGACACGGTTATCAGTACTGCTGATATTATTACCTCATTAATCAAACAAAAAATTTCTGTTG
AAGATATCTCTAATATATTTTCCCTTGAAGAAGGAAAAGTAACGGTAATGGAAGTTAAAATCAGCTCCAATTTTCCTGTA
ACAGGTCAAAAACTTCAAGATATACCTTTGCCTAGGCAATCTATCATAGGATGTATTATTCGAAATAGTGAATCAATTGT
TCCTAGTGGAGATACTGCGATTGAAGTAGGGGATAAGCTCTTAATACTATCCTTGCCAGAAGTACAATCAAAAGTATTAC
AAACAATAAGAGGAAGGCTTGATTAG

Upstream 100 bases:

>100_bases
TAAAAACTATTAGTTCCTATGATCTAGTTTCTAAGGCATTTACTGATTTAATATTGAGCAAATAGAGAAGGTTTACTAAA
TATACCTGGAGGGTTTAGAG

Downstream 100 bases:

>100_bases
TATGAAATACAAAGAAATACTGATTAGAAAATATAATTATATAATAGGATATATAGGAGTAATCTTACTTGGTTTAAGTA
TAGCTTTACTATTACCTTTG

Product: TrkA-N domain protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKIILVGGGNKVHYLAKTFISQGHELTLINNEKEYCRDLAKRFDVNIVYGDGTKPNILEDAEVLTADLVMAVTPKDPDNL
VICQLANKVYEVDKTFAIVNDPDNIEIFKKLGVDTVISTADIITSLIKQKISVEDISNIFSLEEGKVTVMEVKISSNFPV
TGQKLQDIPLPRQSIIGCIIRNSESIVPSGDTAIEVGDKLLILSLPEVQSKVLQTIRGRLD

Sequences:

>Translated_221_residues
MKIILVGGGNKVHYLAKTFISQGHELTLINNEKEYCRDLAKRFDVNIVYGDGTKPNILEDAEVLTADLVMAVTPKDPDNL
VICQLANKVYEVDKTFAIVNDPDNIEIFKKLGVDTVISTADIITSLIKQKISVEDISNIFSLEEGKVTVMEVKISSNFPV
TGQKLQDIPLPRQSIIGCIIRNSESIVPSGDTAIEVGDKLLILSLPEVQSKVLQTIRGRLD
>Mature_221_residues
MKIILVGGGNKVHYLAKTFISQGHELTLINNEKEYCRDLAKRFDVNIVYGDGTKPNILEDAEVLTADLVMAVTPKDPDNL
VICQLANKVYEVDKTFAIVNDPDNIEIFKKLGVDTVISTADIITSLIKQKISVEDISNIFSLEEGKVTVMEVKISSNFPV
TGQKLQDIPLPRQSIIGCIIRNSESIVPSGDTAIEVGDKLLILSLPEVQSKVLQTIRGRLD

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=213, Percent_Identity=27.6995305164319, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24336; Mature: 24336

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIILVGGGNKVHYLAKTFISQGHELTLINNEKEYCRDLAKRFDVNIVYGDGTKPNILED
CEEEEEECCCEEHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCH
AEVLTADLVMAVTPKDPDNLVICQLANKVYEVDKTFAIVNDPDNIEIFKKLGVDTVISTA
HHHHEEEEEEEECCCCCCCEEEEEHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHHHHHH
DIITSLIKQKISVEDISNIFSLEEGKVTVMEVKISSNFPVTGQKLQDIPLPRQSIIGCII
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHCCCCCCHHHHHEEEE
RNSESIVPSGDTAIEVGDKLLILSLPEVQSKVLQTIRGRLD
ECCCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIILVGGGNKVHYLAKTFISQGHELTLINNEKEYCRDLAKRFDVNIVYGDGTKPNILED
CEEEEEECCCEEHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCH
AEVLTADLVMAVTPKDPDNLVICQLANKVYEVDKTFAIVNDPDNIEIFKKLGVDTVISTA
HHHHEEEEEEEECCCCCCCEEEEEHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHHHHHH
DIITSLIKQKISVEDISNIFSLEEGKVTVMEVKISSNFPVTGQKLQDIPLPRQSIIGCII
HHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHCCCCCCHHHHHEEEE
RNSESIVPSGDTAIEVGDKLLILSLPEVQSKVLQTIRGRLD
ECCCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]