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The map label for this gene is yycG [H]

Identifier: 188584892

GI number: 188584892

Start: 264590

End: 266428

Strand: Direct

Name: yycG [H]

Synonym: Nther_0250

Alternate gene names: 188584892

Gene position: 264590-266428 (Clockwise)

Preceding gene: 188584891

Following gene: 188584893

Centisome position: 8.36

GC content: 32.25

Gene sequence:

>1839_bases
ATGTTAAGAAGTATTAGAATAAAAATTTTAGGTGTTATAGCTTTGTTGCTGATAGTATTAGCTATTAACTCCTCGTGGGC
AGTGAATAACTTTCAAATGTTAGATGATTCAATTGAAGCTATAATGCAGGCAAATTATAGAAGTGTGGATGCTGCTCAAA
ATATGATTGTAGCATTAGAAAGACAAGACAGTGCAATTTTAACCTATCTTTTCGAGGAAGATGAAGATATATCTCAAACT
TTTAGGGAACATGAACGAGAGTTTATGAAATGGTTTACACTAGCTGATGATAATATTACTGAAGTTGATGAACCTGAAAT
TATAGAAAATATTGATAATAGTTACGCTGAATTTGCCCTAGAATTTAATAAATTACAGAACATCCAAGTTGAAGAGGGAA
CTGATGCAGCAAGACAACATTATTATGATCAAGTATTCCCAAAGTTTGAAGACGCAAAAGACTTTACTAGAAGACTTTTA
GAGCTAAATCAAAATAAAATGTTAGAATTACAAGGTCAAGCTGAAACAAGGGCGAGTAATGCAACTAAAACAACTGCAAT
AATTTCAATATTAACTGTTGTAACTGGAACAGTGCTAGCACTTTATATAAGTGGTAAAATTACACGTCCAATACGAGATT
TGACAAAGAAAATGGAGAAAGTTTCTCAAGGAGACTACCAACAACAATTGGATATTCAGGGCAACGATGAAATAGTAAAG
TTAGCAGATTCTTTTAACACCATGGCAAAACAACTTAATGAGTATACTAAAATGAATGTATCTAAACTAAAAAGAGAAAA
ACAAAAGGCGGAAGCAATAGTCCAAAGCATCGGTGATGGAATAATTGTTACGAACGAAGATAATAAAATTATACTTGTAA
ATAAAGCAGCAGAAGATGTATTTGACATTAGAGAAAAAGAAGTTATAGATACACACTTCTTAGAAGCATTAAACAATCAA
GAAATCTTTGATTTAATCAAGAAAAGTAAAGATGAGTCACAATTATACTATAAAAGCTATACAGATATTTCTATGATAAA
AGATGGAGATACAAACTACTATAGGATAATTGTGAACCCAATAAAAGCCAAAGATAGTAAAACTATGGGTGTAATAACTT
TAATACAAGATATTACCAAACTAAAGAAAGTTGACGAATTAAAATCTCAGTTTGTTTCAACTGTGTCTCATGAGTTTAGA
ACACCTTTGACATCAATTAATATGTCTATAGGTTTACTACTTGATAAAATTCCTGGTGACATAAATGATGATCAAAAAGA
ACTCTTGCAGGTAATACAGGAAGACAGTGAGCGTTTGAACCGTTTAGTCAATGAATTGCTAGATTTATCTAGGATAGAGT
CAGGAAAAATGCAAATGGATTTTGATTATTACGATATTAAAAATATCATACAACATGCCGTAAAACCATTGCGCATTCAA
GCAGAAGAAAAAAATATACAGATCAAAATTAATGTATCGGATAACCTACCTAAAGTAAGAGCTGACCACACTAAAATTGG
TTGGGTTGTTTCTAACTTGGTAGGCAATGCCTTGAGATATACTCCAACAGATGGTACTGGGGTTATAAACATTGAAACCA
AACAAACTGCTAATAAAATTGTCACTTCAGTAACTGATAATGGCTCAGGTATTTCAGAAGAATATCAAAAAATAATTTTT
GATAAGTTTTTACAAGTAAATGGAGGAGAGTCGACCCAAGGTGGAGCTGGACTAGGTCTTGCAATCAGTCGGGAAATTGT
AAGAGCTCATGGCGGTGATATGTGGGTTGACAGTGAACTTGGTGAAGGTAGTACATTCTATTTCACTTTAAATATGTAA

Upstream 100 bases:

>100_bases
GCGTTTGAAGGGGCTTACTATGTTATAAAAACCATAGGGAGTTACCCCTATGGTTTTTTAATGGAATTATTAATAACTCA
TACAAAAAGAAGGTGTCATT

Downstream 100 bases:

>100_bases
TTAAATGATATTTGTAAATTGCGAGAGGGGAGGCTTTATATGCCAAAAATATTAGTTATTGAAGATGAAAAAAATATAGT
TATCCCTTTAAAGCTATATC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MLRSIRIKILGVIALLLIVLAINSSWAVNNFQMLDDSIEAIMQANYRSVDAAQNMIVALERQDSAILTYLFEEDEDISQT
FREHEREFMKWFTLADDNITEVDEPEIIENIDNSYAEFALEFNKLQNIQVEEGTDAARQHYYDQVFPKFEDAKDFTRRLL
ELNQNKMLELQGQAETRASNATKTTAIISILTVVTGTVLALYISGKITRPIRDLTKKMEKVSQGDYQQQLDIQGNDEIVK
LADSFNTMAKQLNEYTKMNVSKLKREKQKAEAIVQSIGDGIIVTNEDNKIILVNKAAEDVFDIREKEVIDTHFLEALNNQ
EIFDLIKKSKDESQLYYKSYTDISMIKDGDTNYYRIIVNPIKAKDSKTMGVITLIQDITKLKKVDELKSQFVSTVSHEFR
TPLTSINMSIGLLLDKIPGDINDDQKELLQVIQEDSERLNRLVNELLDLSRIESGKMQMDFDYYDIKNIIQHAVKPLRIQ
AEEKNIQIKINVSDNLPKVRADHTKIGWVVSNLVGNALRYTPTDGTGVINIETKQTANKIVTSVTDNGSGISEEYQKIIF
DKFLQVNGGESTQGGAGLGLAISREIVRAHGGDMWVDSELGEGSTFYFTLNM

Sequences:

>Translated_612_residues
MLRSIRIKILGVIALLLIVLAINSSWAVNNFQMLDDSIEAIMQANYRSVDAAQNMIVALERQDSAILTYLFEEDEDISQT
FREHEREFMKWFTLADDNITEVDEPEIIENIDNSYAEFALEFNKLQNIQVEEGTDAARQHYYDQVFPKFEDAKDFTRRLL
ELNQNKMLELQGQAETRASNATKTTAIISILTVVTGTVLALYISGKITRPIRDLTKKMEKVSQGDYQQQLDIQGNDEIVK
LADSFNTMAKQLNEYTKMNVSKLKREKQKAEAIVQSIGDGIIVTNEDNKIILVNKAAEDVFDIREKEVIDTHFLEALNNQ
EIFDLIKKSKDESQLYYKSYTDISMIKDGDTNYYRIIVNPIKAKDSKTMGVITLIQDITKLKKVDELKSQFVSTVSHEFR
TPLTSINMSIGLLLDKIPGDINDDQKELLQVIQEDSERLNRLVNELLDLSRIESGKMQMDFDYYDIKNIIQHAVKPLRIQ
AEEKNIQIKINVSDNLPKVRADHTKIGWVVSNLVGNALRYTPTDGTGVINIETKQTANKIVTSVTDNGSGISEEYQKIIF
DKFLQVNGGESTQGGAGLGLAISREIVRAHGGDMWVDSELGEGSTFYFTLNM
>Mature_612_residues
MLRSIRIKILGVIALLLIVLAINSSWAVNNFQMLDDSIEAIMQANYRSVDAAQNMIVALERQDSAILTYLFEEDEDISQT
FREHEREFMKWFTLADDNITEVDEPEIIENIDNSYAEFALEFNKLQNIQVEEGTDAARQHYYDQVFPKFEDAKDFTRRLL
ELNQNKMLELQGQAETRASNATKTTAIISILTVVTGTVLALYISGKITRPIRDLTKKMEKVSQGDYQQQLDIQGNDEIVK
LADSFNTMAKQLNEYTKMNVSKLKREKQKAEAIVQSIGDGIIVTNEDNKIILVNKAAEDVFDIREKEVIDTHFLEALNNQ
EIFDLIKKSKDESQLYYKSYTDISMIKDGDTNYYRIIVNPIKAKDSKTMGVITLIQDITKLKKVDELKSQFVSTVSHEFR
TPLTSINMSIGLLLDKIPGDINDDQKELLQVIQEDSERLNRLVNELLDLSRIESGKMQMDFDYYDIKNIIQHAVKPLRIQ
AEEKNIQIKINVSDNLPKVRADHTKIGWVVSNLVGNALRYTPTDGTGVINIETKQTANKIVTSVTDNGSGISEEYQKIIF
DKFLQVNGGESTQGGAGLGLAISREIVRAHGGDMWVDSELGEGSTFYFTLNM

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788713, Length=369, Percent_Identity=27.6422764227642, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI48994928, Length=388, Percent_Identity=25.2577319587629, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786600, Length=350, Percent_Identity=26, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=30.8016877637131, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=29.4871794871795, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=31.1111111111111, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=384, Percent_Identity=22.9166666666667, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=25.2136752136752, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=28.9795918367347, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=28.9473684210526, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=26.605504587156, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=27.0742358078603, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=204, Percent_Identity=28.921568627451, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=25.4807692307692, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=22.6628895184136, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=26.0162601626016, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69480; Mature: 69480

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSIRIKILGVIALLLIVLAINSSWAVNNFQMLDDSIEAIMQANYRSVDAAQNMIVALE
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEE
RQDSAILTYLFEEDEDISQTFREHEREFMKWFTLADDNITEVDEPEIIENIDNSYAEFAL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHHHH
EFNKLQNIQVEEGTDAARQHYYDQVFPKFEDAKDFTRRLLELNQNKMLELQGQAETRASN
HHHHHCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHCCC
ATKTTAIISILTVVTGTVLALYISGKITRPIRDLTKKMEKVSQGDYQQQLDIQGNDEIVK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHH
LADSFNTMAKQLNEYTKMNVSKLKREKQKAEAIVQSIGDGIIVTNEDNKIILVNKAAEDV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCHHHH
FDIREKEVIDTHFLEALNNQEIFDLIKKSKDESQLYYKSYTDISMIKDGDTNYYRIIVNP
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEEEEEEE
IKAKDSKTMGVITLIQDITKLKKVDELKSQFVSTVSHEFRTPLTSINMSIGLLLDKIPGD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCC
INDDQKELLQVIQEDSERLNRLVNELLDLSRIESGKMQMDFDYYDIKNIIQHAVKPLRIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEE
AEEKNIQIKINVSDNLPKVRADHTKIGWVVSNLVGNALRYTPTDGTGVINIETKQTANKI
EECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEECHHHHHHH
VTSVTDNGSGISEEYQKIIFDKFLQVNGGESTQGGAGLGLAISREIVRAHGGDMWVDSEL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCC
GEGSTFYFTLNM
CCCCEEEEEEEC
>Mature Secondary Structure
MLRSIRIKILGVIALLLIVLAINSSWAVNNFQMLDDSIEAIMQANYRSVDAAQNMIVALE
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEE
RQDSAILTYLFEEDEDISQTFREHEREFMKWFTLADDNITEVDEPEIIENIDNSYAEFAL
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHHHH
EFNKLQNIQVEEGTDAARQHYYDQVFPKFEDAKDFTRRLLELNQNKMLELQGQAETRASN
HHHHHCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHCCC
ATKTTAIISILTVVTGTVLALYISGKITRPIRDLTKKMEKVSQGDYQQQLDIQGNDEIVK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHH
LADSFNTMAKQLNEYTKMNVSKLKREKQKAEAIVQSIGDGIIVTNEDNKIILVNKAAEDV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCHHHH
FDIREKEVIDTHFLEALNNQEIFDLIKKSKDESQLYYKSYTDISMIKDGDTNYYRIIVNP
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEEEEEEE
IKAKDSKTMGVITLIQDITKLKKVDELKSQFVSTVSHEFRTPLTSINMSIGLLLDKIPGD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCC
INDDQKELLQVIQEDSERLNRLVNELLDLSRIESGKMQMDFDYYDIKNIIQHAVKPLRIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCEEEE
AEEKNIQIKINVSDNLPKVRADHTKIGWVVSNLVGNALRYTPTDGTGVINIETKQTANKI
EECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEECHHHHHHH
VTSVTDNGSGISEEYQKIIFDKFLQVNGGESTQGGAGLGLAISREIVRAHGGDMWVDSEL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCC
GEGSTFYFTLNM
CCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]