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The map label for this gene is zupT [H]

Identifier: 188584678

GI number: 188584678

Start: 49918

End: 50661

Strand: Reverse

Name: zupT [H]

Synonym: Nther_0036

Alternate gene names: 188584678

Gene position: 50661-49918 (Counterclockwise)

Preceding gene: 188584682

Following gene: 188584670

Centisome position: 1.6

GC content: 40.46

Gene sequence:

>744_bases
ATGGAAGCTTTAGTCTATAGTTTTTTAGCTGGTATTTCTACAGCCATAGGAGCTATAATAGTAGCTTTTTTTGGACAACC
TAGTCAAAGGGCTTTATCTGGTCTATTAGGATTTGCAGGTGGTATTATGCTAGCTATATCAGCCTTCGACTTAATGCCAG
AGTCCTTAGAGATAGGTTCGATGTCGTCGACTATTATTGGCTTTTCCTTTGGGGCAATTATGATGTATGCACTTGATAAA
TTTATTCCCCACGCCCATATGTCAGGAGGAGAAGACATAATTGAAGAAAACACATCCCCTTTGAATAACAAAGAAATTCT
TCGTACCGGTTACCTAATTTTCTTTGGAATAGCTCTACACAATTTACCCGAAGGTTTAGCCATTGGTGCCGGATTAGAAT
CGAGCCCAGAACTTGGACTATATATTGCCATTGCCATCGGTCTTCATAATATACCAGAGGGCATGGCTACTGCAGGGCCT
TTAAGAGCAGGAGGTTTACGCTGGATTAAAGTTTTCTTACTCACCTTATTTGCCGGACTTATGACACCATTAGGAGCTGC
CCTGGGATTAATCATCTTCAATATATCACCTGTTCTCGTTGCAGGGGGACTAGCTTTTGCAGCTGGTGCAATGGTCTATA
TAGTAAGTGATGAATTAATCCCACAATCCCATAACCTACATAGTCACATTGCTAATGCTGGATTAATAATCGGTCTGCTT
TTGGGTTTTGTATTGACTAGTTAA

Upstream 100 bases:

>100_bases
GGTTTTGATTTCTGTCTAAAACTATCTTAACTCCGGGACGGAGACTGATTCAAATATCATATAACTTAACAGAACTTTAT
TATAAGCTAGGAGGTTTGTT

Downstream 100 bases:

>100_bases
GCAATTATTTATCAGTAAGCGTCGTAAGAGCTTATTAAGTTGAATTTTTGTTTTTCAAAAATTAAGCTCCTTCTAGATTT
ATTGATATAAATCCAGAAGG

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEALVYSFLAGISTAIGAIIVAFFGQPSQRALSGLLGFAGGIMLAISAFDLMPESLEIGSMSSTIIGFSFGAIMMYALDK
FIPHAHMSGGEDIIEENTSPLNNKEILRTGYLIFFGIALHNLPEGLAIGAGLESSPELGLYIAIAIGLHNIPEGMATAGP
LRAGGLRWIKVFLLTLFAGLMTPLGAALGLIIFNISPVLVAGGLAFAAGAMVYIVSDELIPQSHNLHSHIANAGLIIGLL
LGFVLTS

Sequences:

>Translated_247_residues
MEALVYSFLAGISTAIGAIIVAFFGQPSQRALSGLLGFAGGIMLAISAFDLMPESLEIGSMSSTIIGFSFGAIMMYALDK
FIPHAHMSGGEDIIEENTSPLNNKEILRTGYLIFFGIALHNLPEGLAIGAGLESSPELGLYIAIAIGLHNIPEGMATAGP
LRAGGLRWIKVFLLTLFAGLMTPLGAALGLIIFNISPVLVAGGLAFAAGAMVYIVSDELIPQSHNLHSHIANAGLIIGLL
LGFVLTS
>Mature_247_residues
MEALVYSFLAGISTAIGAIIVAFFGQPSQRALSGLLGFAGGIMLAISAFDLMPESLEIGSMSSTIIGFSFGAIMMYALDK
FIPHAHMSGGEDIIEENTSPLNNKEILRTGYLIFFGIALHNLPEGLAIGAGLESSPELGLYIAIAIGLHNIPEGMATAGP
LRAGGLRWIKVFLLTLFAGLMTPLGAALGLIIFNISPVLVAGGLAFAAGAMVYIVSDELIPQSHNLHSHIANAGLIIGLL
LGFVLTS

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=317, Percent_Identity=26.4984227129338, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI229577422, Length=306, Percent_Identity=26.1437908496732, Blast_Score=85, Evalue=6e-17,
Organism=Escherichia coli, GI1789419, Length=250, Percent_Identity=39.2, Blast_Score=127, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17507805, Length=303, Percent_Identity=29.042904290429, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24652846, Length=159, Percent_Identity=32.0754716981132, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 25681; Mature: 25681

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALVYSFLAGISTAIGAIIVAFFGQPSQRALSGLLGFAGGIMLAISAFDLMPESLEIGS
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MSSTIIGFSFGAIMMYALDKFIPHAHMSGGEDIIEENTSPLNNKEILRTGYLIFFGIALH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NLPEGLAIGAGLESSPELGLYIAIAIGLHNIPEGMATAGPLRAGGLRWIKVFLLTLFAGL
CCCCCCEECCCCCCCCCCCEEEEEEEHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHH
MTPLGAALGLIIFNISPVLVAGGLAFAAGAMVYIVSDELIPQSHNLHSHIANAGLIIGLL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGFVLTS
HHHHHCC
>Mature Secondary Structure
MEALVYSFLAGISTAIGAIIVAFFGQPSQRALSGLLGFAGGIMLAISAFDLMPESLEIGS
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
MSSTIIGFSFGAIMMYALDKFIPHAHMSGGEDIIEENTSPLNNKEILRTGYLIFFGIALH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NLPEGLAIGAGLESSPELGLYIAIAIGLHNIPEGMATAGPLRAGGLRWIKVFLLTLFAGL
CCCCCCEECCCCCCCCCCCEEEEEEEHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHH
MTPLGAALGLIIFNISPVLVAGGLAFAAGAMVYIVSDELIPQSHNLHSHIANAGLIIGLL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGFVLTS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA