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The map label for this gene is ribE [H]

Identifier: 188528366

GI number: 188528366

Start: 1597248

End: 1597868

Strand: Direct

Name: ribE [H]

Synonym: HPSH_08200

Alternate gene names: 188528366

Gene position: 1597248-1597868 (Clockwise)

Preceding gene: 188528356

Following gene: 188528367

Centisome position: 99.3

GC content: 40.1

Gene sequence:

>621_bases
ATGTTCAGCGGCCTAATCCATCAAATAGCTAGAGTGAAAAGTTTCCAAAACAATATTTTAAGCATAGAGAGCGATCTCAA
TCCCAAGCTTGGCGATAGCATTGCGATCAATGGGGCGTGTTTGACCGCCATAGAAAGTTCAAAAACGCATTTTAGCGTGG
AATTGAGCCAAAAAACCCAAAACAGCGTAGCGTTAGAAAATTACAAGGATTTAGTCCATATTGAGCCAGCCCTAAAAGCC
GATGCGAGTTTGGATGGGCATTTTGTGCAAGGGCATATTGACGCTATTGGGGTAATTGAAAAAATCATTCATTATTCTAA
TCAAGTGGATTTTTTCATCAGCGCTTCTAAAGAAACGCTTTTATTGTGCGTTGAGCAAGGCTCTATCGCCATTGATGGGG
TGAGTTTGACTTTAAGCAAGGTAGAAGAAAAGGGGTTTTGGCTAACGATTATCCCTTACACTTTAGAAAACACCCTTTTT
AAGACTTACAAACTCAAACGGCGCGTGAATATTGAAACGGACATGCTGGTTCGTAGCGTTGCGTCTATTTTGAAAAAAAC
AAAAGGGTTTGAAAAAAATTTCTCTTGGAATGACGCTGACGCTTTGACTTTAGGGTATTAG

Upstream 100 bases:

>100_bases
AAATGGCAATGCGTGTCAATAAACATGCTTTTATCCTGTGGTTTTATTTAATATGTTACAATACTTAAGCATTTTAACAT
AAGGAAAATAATCATTAACG

Downstream 100 bases:

>100_bases
ATGAATAAAACCATAAAAGCCGCCGCTCTAGCCTATAACATGGGGCAAGATCATGCCCCAAAAGTGATCGCAAGCGGGGT
GGGCGAAGTGGCTAAAAGGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MFSGLIHQIARVKSFQNNILSIESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHYSNQVDFFISASKETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADALTLGY

Sequences:

>Translated_206_residues
MFSGLIHQIARVKSFQNNILSIESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHYSNQVDFFISASKETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADALTLGY
>Mature_206_residues
MFSGLIHQIARVKSFQNNILSIESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQNSVALENYKDLVHIEPALKA
DASLDGHFVQGHIDAIGVIEKIIHYSNQVDFFISASKETLLLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLF
KTYKLKRRVNIETDMLVRSVASILKKTKGFEKNFSWNDADALTLGY

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=30.3921568627451, Blast_Score=89, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=153, Percent_Identity=35.9477124183007, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22893; Mature: 22893

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGLIHQIARVKSFQNNILSIESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQ
CCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCCCC
NSVALENYKDLVHIEPALKADASLDGHFVQGHIDAIGVIEKIIHYSNQVDFFISASKETL
CCEEHHCCCCEEEECCHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCEE
LLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLFKTYKLKRRVNIETDMLVRSV
EEEEECCCEEEECCEEEEEHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ASILKKTKGFEKNFSWNDADALTLGY
HHHHHHHCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MFSGLIHQIARVKSFQNNILSIESDLNPKLGDSIAINGACLTAIESSKTHFSVELSQKTQ
CCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCEEEEEEECCCCEEEEEECCCCC
NSVALENYKDLVHIEPALKADASLDGHFVQGHIDAIGVIEKIIHYSNQVDFFISASKETL
CCEEHHCCCCEEEECCHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCEE
LLCVEQGSIAIDGVSLTLSKVEEKGFWLTIIPYTLENTLFKTYKLKRRVNIETDMLVRSV
EEEEECCCEEEECCEEEEEHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ASILKKTKGFEKNFSWNDADALTLGY
HHHHHHHCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]