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The map label for this gene is ftsW [H]

Identifier: 188528352

GI number: 188528352

Start: 1584538

End: 1585704

Strand: Direct

Name: ftsW [H]

Synonym: HPSH_08130

Alternate gene names: 188528352

Gene position: 1584538-1585704 (Clockwise)

Preceding gene: 188528346

Following gene: 188528355

Centisome position: 98.51

GC content: 44.64

Gene sequence:

>1167_bases
ATGACTACAGACAAAAGCCTGTTTTTTTGCGCTTCGCTATTGATTTTTTTGGGGGTATTGATGAGCTATTCGCTCTCAAC
TTACACCACAGTGGTGCTGTATCATTATGGGGAATTCCATTTTTTCATACGACAGCTTGTGAGCGCGATCATGGGGATTG
TTATCATGTGGGGGTTGTCTAGGGTTGATCCTAGCAAGTGGTTTGGCCGTTTGGGGTTTTTTCTTCTCTTTATCCCATTA
TTACTCATTATTGGCATGTTTTTTTTGCCAGAAAGCCTTTCCAGTAGTGCGGGAGGGGCGAAGCGATGGATTCGTTTGGG
GTTTTTCTCGCTCGCACCCTTGGAGTTTTTAAAGATTGGTTTCACTTTTTTTCTTGCGTGGAGTTTGTCTCGCACCTTTG
TGGCAAAAGAAAAGGCTAGTGTTAAAGAAGAACTGATCATTTTTGGGCCTTATTCAGTGGTGTTTGTGGTATTAGCGGTT
GGGGTGGGGTTTTTGCAAAACGATTTGGGGCAGATCATTCTTTTGGGGGCAGTTTTAATCATGCTATTAGTCTTTTCTGG
AGGGAGCGCGCATTTGTTTGGCTTGATTGTTTTAGGGGCGCTTGCGATCAGCGTTTTAGCGATTGTTACAAGCCCTCATA
GGATCTTGCGCGTGAAATTGTGGTGGTCTAATTTGCAAAATTCGCTTTTCACGCTTTTGCCGGATAAATTAGCGAACGCT
CTTAGAATAAGCGACTTGCCCGAATCCTATCAAGTCTTTCATGCAGGCAACGCCATGCATAATGGGGGGTTGTTTGGGCA
AGGGCTTGGGCTAGGGCAAATCAAGCTTGGGTTTTTGAGCGAAGTGCATACGGATATGGTTCTAGCTGGGATCGCCGAAG
AATGGGGGTTTTTGGGGCTATGCGTTTGTTTTATTTTGTTTTCTGTTTTGATTGTTTTGATTTTTAGGATCGCTAACCGC
TTGAAAGAGCCAAAATACTCGCTATTTTGCGTGGGTGTGGCACTACTCATCAGTTTTTCTTTAGTGATCAACGCCTTTGG
GGTGGGAGGGATTTTTCCGGTTAAAGGTCTAGCGGTGCCGTTTTTGAGCTATGGAGGGAGTTCGCTTTTAGCGAATTGTA
TCGCTATAGGGCTTGTTTTAAGCCTAGCGCGATACACGAAGGGCTAA

Upstream 100 bases:

>100_bases
AGCTTGAGTGCTAAGATAATTCAGAGCCATTATAGTGTAAAATACCCCTAAAATACCTTAAGATAACGCCTATTTAAAAA
ACCAAGATAAGGAAATCCTA

Downstream 100 bases:

>100_bases
AAAATACTAGCCCTTTTTAAAGATTAATGCCATAAAAAGGGTTCAATTTCTGCATCTTTCAAATCAAAAACCACTTTATA
GTAGTCTTTAACAATCGCAT

Product: putative rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTTDKSLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIMGIVIMWGLSRVDPSKWFGRLGFFLLFIPL
LLIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIGFTFFLAWSLSRTFVAKEKASVKEELIIFGPYSVVFVVLAV
GVGFLQNDLGQIILLGAVLIMLLVFSGGSAHLFGLIVLGALAISVLAIVTSPHRILRVKLWWSNLQNSLFTLLPDKLANA
LRISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGLCVCFILFSVLIVLIFRIANR
LKEPKYSLFCVGVALLISFSLVINAFGVGGIFPVKGLAVPFLSYGGSSLLANCIAIGLVLSLARYTKG

Sequences:

>Translated_388_residues
MTTDKSLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIMGIVIMWGLSRVDPSKWFGRLGFFLLFIPL
LLIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIGFTFFLAWSLSRTFVAKEKASVKEELIIFGPYSVVFVVLAV
GVGFLQNDLGQIILLGAVLIMLLVFSGGSAHLFGLIVLGALAISVLAIVTSPHRILRVKLWWSNLQNSLFTLLPDKLANA
LRISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGLCVCFILFSVLIVLIFRIANR
LKEPKYSLFCVGVALLISFSLVINAFGVGGIFPVKGLAVPFLSYGGSSLLANCIAIGLVLSLARYTKG
>Mature_387_residues
TTDKSLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIMGIVIMWGLSRVDPSKWFGRLGFFLLFIPLL
LIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIGFTFFLAWSLSRTFVAKEKASVKEELIIFGPYSVVFVVLAVG
VGFLQNDLGQIILLGAVLIMLLVFSGGSAHLFGLIVLGALAISVLAIVTSPHRILRVKLWWSNLQNSLFTLLPDKLANAL
RISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGLCVCFILFSVLIVLIFRIANRL
KEPKYSLFCVGVALLISFSLVINAFGVGGIFPVKGLAVPFLSYGGSSLLANCIAIGLVLSLARYTKG

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786853, Length=350, Percent_Identity=28, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42394; Mature: 42263

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDKSLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIMGIVIMWGLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RVDPSKWFGRLGFFLLFIPLLLIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FTFFLAWSLSRTFVAKEKASVKEELIIFGPYSVVFVVLAVGVGFLQNDLGQIILLGAVLI
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLVFSGGSAHLFGLIVLGALAISVLAIVTSPHRILRVKLWWSNLQNSLFTLLPDKLANA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHH
LRISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGL
HHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVCFILFSVLIVLIFRIANRLKEPKYSLFCVGVALLISFSLVINAFGVGGIFPVKGLAVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FLSYGGSSLLANCIAIGLVLSLARYTKG
HHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTDKSLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIMGIVIMWGLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RVDPSKWFGRLGFFLLFIPLLLIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FTFFLAWSLSRTFVAKEKASVKEELIIFGPYSVVFVVLAVGVGFLQNDLGQIILLGAVLI
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLVFSGGSAHLFGLIVLGALAISVLAIVTSPHRILRVKLWWSNLQNSLFTLLPDKLANA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHH
LRISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGL
HHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVCFILFSVLIVLIFRIANRLKEPKYSLFCVGVALLISFSLVINAFGVGGIFPVKGLAVP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FLSYGGSSLLANCIAIGLVLSLARYTKG
HHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]