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The map label for this gene is secD

Identifier: 188528335

GI number: 188528335

Start: 1565031

End: 1566608

Strand: Direct

Name: secD

Synonym: HPSH_08035

Alternate gene names: 188528335

Gene position: 1565031-1566608 (Clockwise)

Preceding gene: 188528334

Following gene: 188528336

Centisome position: 97.29

GC content: 43.35

Gene sequence:

>1578_bases
ATGAAACTTTTTAACCCTCGCTTAATCGTTTTTATTTGCGCGCTTCTTTTAGGGGTAGGGTTTTCTGTGCCTTCTTTGCT
AGAGACTAAAGGCCCTAAAATCACTCTAGGTTTGGATTTAAGGGGGGGGTTAAACATGCTTTTAGGGGTGCAAACCGATG
AGGCTTTAAAAAACAAGTATTTAAGCTTGGCGTCCGCTTTAGAATACAACGCTAAAAAGCAAAATATCTTGCTTAAAGAC
ATTAAATCCAGTCTAGAAGGGATCAGTTTTGAGCTTTTAGATGAAGATGAAGCGAAAAAATTAGACGCGCTTTTAGTGGA
ATTGCAAGGTCATAGCCAGTTTGAAATCAAAAAAGAAGCGGAATTTTATAGCGTGAAGCTCACCCCTTTAGAGCAAGAGG
AATTGCGTAAAAACACGATTTTGCAAGTGATAGGGATCATTCGTAACCGCTTGGATCAATTTGGCTTGGCAGAGCCTATA
GTCATTCAGCAAGGTAAAGAAGAAATTTCGGTGCAATTGCCCGGCATTAAGACTTTAGAAGAAGAAAGGCGCGCTAAAGA
GTTGATCTCTCGATCCGCTCATTTGCAGATGATGGCAGTGGATGAAGAACACAATAAAGATGCGATGAAAATGACGGATT
TAGAGGCTCAAAAATTAGGCAGCGTGTTGTTATCGGATGTGGAAATGGGGGGTAAAATCTTGCTCAAAGCGATCCCTATT
TTAGATGGCGAAATGCTTACGGATGCGAAAGTGGTGTATGATCAAAACAACCAGCCGGTGGTGAGCTTCACGCTAGATGC
GCAAGGGGCTAAGATTTTTGGGGATTTCTCAGGCACGAATGTGGGCAAACGCATGGCGATTGTTTTAGACAACAAGGTCT
ATTCAGCCCCAGTGATCAGAGAGCGTATTGGCGGAGGGAGCGGGCAAATTAGCGGGAATTTTAGCGTGGCTCAAGCGAGC
GATTTAGCGATCGCTTTAAGGAGTGGGGCGATGAGCGCTCCCATTCAGGTTTTAGAAAAAAGGATTATAGGCCCGAGTTT
AGGGAAAGACAGCATTAAAACTTCCATTATCGCTCTAGTTGGGGGCTTTATTTTGGTGATGGGCTTTATGGTGCTTTATT
ACTCTATGGCGGGGGTGATCGCTTGCATGGCGTTAGTGGTCAATCTTTTTTTGATTGTGGCGGTCATGGCGATTTTTGGA
GCGACTCTGACTTTACCGGGAATGGCGGGGATTGTTTTAACCGTGGGGATTGCTGTGGATGCTAATATCATTATCAATGA
GCGTATTAGAGAGGTTTTAAGAGAGAATGAAGGCATCGCTAAGGCGATCCATTTAGGCTATATCAATGCAAGCCGGGCGA
TTTTTGATTCTAATATCACTTCCTTGATCGCTTCAGTGTTATTATACGCTTATGGCACAGGAGCGATTAAAGGCTTTGCC
CTAACCACAGGCATTGGGATTTTAGCCTCTATTATCACCGCTATTGTAGGCACGCAAGGGATTTATCAAGCCCTTTTACC
TAAACTCACCCAAACAAAAAGCCTTTATTTTTGGTTTGGCGTGAATAAAAGAGCTTAG

Upstream 100 bases:

>100_bases
ATTTTTTTAGCGTGAAACTCAATGATGACACCACCGCTAAACTTTCTAAAAACTATATAGCGTTCAAATTAGACGAAGAA
GCGGCGCAAAATAACAACTA

Downstream 100 bases:

>100_bases
GAGTTTTTATGGAATTATTCAAACAAACTAGAATCTTAAACTTCATGCGTTATTCCAATTATGGGGTGGTTGTTTCAGCG
ATCTTAGCACTTTTAGCGTT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKLFNPRLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPI
VIQQGKEEISVQLPGIKTLEEERRAKELISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGTNVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMVLYYSMAGVIACMALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Sequences:

>Translated_525_residues
MKLFNPRLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPI
VIQQGKEEISVQLPGIKTLEEERRAKELISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGTNVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMVLYYSMAGVIACMALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
>Mature_525_residues
MKLFNPRLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGISFELLDEDEAKKLDALLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPI
VIQQGKEEISVQLPGIKTLEEERRAKELISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGTNVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALVGGFILVMGFMVLYYSMAGVIACMALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=505, Percent_Identity=37.4257425742574, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 56786; Mature: 56786

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFNPRLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGISFELLDEDEAKKLDALLVELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPIVIQQGKEEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCHHHH
EERRAKELISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGTNVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALV
HHCCCCCCEECCCEEEECCCCHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVMGFMVLYYSMAGVIACMALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC
>Mature Secondary Structure
MKLFNPRLIVFICALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGISFELLDEDEAKKLDALLVELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPIVIQQGKEEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCHHHH
EERRAKELISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGTNVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSIKTSIIALV
HHCCCCCCEECCCEEEECCCCHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVMGFMVLYYSMAGVIACMALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]