Click here to switch to the map view.

The map label for this gene is rocF [H]

Identifier: 188528311

GI number: 188528311

Start: 1543152

End: 1544087

Strand: Reverse

Name: rocF [H]

Synonym: HPSH_07915

Alternate gene names: 188528311

Gene position: 1544087-1543152 (Counterclockwise)

Preceding gene: 188528314

Following gene: 188528309

Centisome position: 95.99

GC content: 40.17

Gene sequence:

>936_bases
ATGATTTTAGTAGGATTGGAAGCGGAATTAGGAGCGTCAAAAAGAGGCACCGATAAAGGGGTTAGGCGTTTGAGAGAAGC
TTTGAGCGCAACGCATGGCGATGTGATTAAAGGCATGCAAACGATCGTTCAAGAGCGGTGCGTGCTTTATAAAGAGTTTA
GATACGCTAAGAATTTTGAAGATTACTACCTTTTTTGTAAAGAAAATTTGATCCCTTGCATGCGAGAAGTGTTTGAGAAA
AAAGAATTTCCTTTGATTTTAAGCTCAGAGCATGCGAACATGTTTGGGATTTTCCAAGCCTTTAGGAGCGTTCATAAGGA
CAAAAAAATAGGGATTTTGTATTTAGACGCGCATGCGGATATTCATACGGCTTATGACAGCGATTCAAAGCATATCCACG
GCATGCCTTTGGGCATGGTTTTAAATCGTGTCCGTAGCGGGTTTAATCGCATGAATGAGAGCGAAGAAAAGGCATGGCAA
AAGCTCTGCTCTTTGGGGTTAGAAAAGGGAGGGTTAGAAATTGATCCTAAATGTTTGGTGTATTTTGGGGTAAGAAGCAC
CGAACAGAGTGAAAGAGATGTGATTAAGGAATTGCAAATCCCTTTATTTAGCGTGGAAGCGATAAGAGAAAACATGCAAG
AAGTGGTTCAAAAAACCAAAGAATCATTAAAAGCGGTGGATATTATTTATCTCAGTTTGGATTTAGACATTATGGATGGC
AAGCTTTTCACTTCTACCGGCGTGCGTGAAAATAACGGGCTGAGTTTTAATGAGTTGAAGCAATTACTGGGCTTGCTTTT
AGAAAGTTTTAAAGACAGATTAAGAGCTGTTGAGGTAACCGAATACAACCCCACGGTGAGGGCAAAACACACCGACGAAG
AAGAAAGGCAGGTTTTAGAGATCTTAGATCTCATCATCAATAGCTGTAAAATTTAA

Upstream 100 bases:

>100_bases
ATAAAATTGTTCTATTTATTATCCATTTGCTTATTAATAATTGGTTGTTAATTTTGGTTTAGAATGGGAAATACGAGTGG
GGATTTAAAGGAGTTGTAAA

Downstream 100 bases:

>100_bases
GAAGCCATCTTTTATAATGAGTCGCTGATCGCTTTTCAAACACAACGATAAAAAGTTAAAAAAAGCTGGAAAATGAAGCC
AACAACAAGAAATGCCAAGA

Product: arginase (rocF)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIKGMQTIVQERCVLYKEFRYAKNFEDYYLFCKENLIPCMREVFEK
KEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMNESEEKAWQ
KLCSLGLEKGGLEIDPKCLVYFGVRSTEQSERDVIKELQIPLFSVEAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDG
KLFTSTGVRENNGLSFNELKQLLGLLLESFKDRLRAVEVTEYNPTVRAKHTDEEERQVLEILDLIINSCKI

Sequences:

>Translated_311_residues
MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIKGMQTIVQERCVLYKEFRYAKNFEDYYLFCKENLIPCMREVFEK
KEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMNESEEKAWQ
KLCSLGLEKGGLEIDPKCLVYFGVRSTEQSERDVIKELQIPLFSVEAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDG
KLFTSTGVRENNGLSFNELKQLLGLLLESFKDRLRAVEVTEYNPTVRAKHTDEEERQVLEILDLIINSCKI
>Mature_311_residues
MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIKGMQTIVQERCVLYKEFRYAKNFEDYYLFCKENLIPCMREVFEK
KEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMNESEEKAWQ
KLCSLGLEKGGLEIDPKCLVYFGVRSTEQSERDVIKELQIPLFSVEAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDG
KLFTSTGVRENNGLSFNELKQLLGLLLESFKDRLRAVEVTEYNPTVRAKHTDEEERQVLEILDLIINSCKI

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=239, Percent_Identity=27.1966527196653, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4502215, Length=205, Percent_Identity=28.780487804878, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996843, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325146, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638886, Length=303, Percent_Identity=26.4026402640264, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 35686; Mature: 35686

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIKGMQTIVQERCVLYKEFRYAKNFE
CEEEEECHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DYYLFCKENLIPCMREVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHAD
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
IHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMNESEEKAWQKLCSLGLEKGGLEIDPKCLV
EEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCEEE
YFGVRSTEQSERDVIKELQIPLFSVEAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDG
EEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECC
KLFTSTGVRENNGLSFNELKQLLGLLLESFKDRLRAVEVTEYNPTVRAKHTDEEERQVLE
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECCCCCHHHHHHHH
ILDLIINSCKI
HHHHHHHHCCC
>Mature Secondary Structure
MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIKGMQTIVQERCVLYKEFRYAKNFE
CEEEEECHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DYYLFCKENLIPCMREVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHAD
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
IHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMNESEEKAWQKLCSLGLEKGGLEIDPKCLV
EEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCEEE
YFGVRSTEQSERDVIKELQIPLFSVEAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDG
EEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECC
KLFTSTGVRENNGLSFNELKQLLGLLLESFKDRLRAVEVTEYNPTVRAKHTDEEERQVLE
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECCCCCHHHHHHHH
ILDLIINSCKI
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]