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The map label for this gene is selA [H]

Identifier: 188528282

GI number: 188528282

Start: 1506690

End: 1507850

Strand: Direct

Name: selA [H]

Synonym: HPSH_07770

Alternate gene names: 188528282

Gene position: 1506690-1507850 (Clockwise)

Preceding gene: 188528281

Following gene: 188528283

Centisome position: 93.67

GC content: 37.38

Gene sequence:

>1161_bases
ATGGCTAAAGAAACGCTCCCAATAACCCCGGATCTTTTGAAAAGCCCTTATCAAAAAATCATCAATGCGAGCGCGAGCGT
TTTTGATGAAAACCATGGGCGATCGTTTTTTAGCACGCAATTTTATGAAACAATTGAACCTTATTTAAAAGAAGTTTTAA
CCCATCCCATTGATTTAGAATGCGATCTAAACACCGCTAAAAAAAAGAACCGCTTAACCCCTTTAAAAAAACTTTTCAAA
GCGTGTTTTAACACCGAAGAAATTTTGATTGTCAATAACAACACCAGCGCGATATTTCTCATTGCTAACGCTTTAGCGCA
AGAAAAAGAAATCGTTGTTTCTTATGGCGAATTAGTGGGGGGGGATTTTAACCTTAAAGACATTTTGTTAAGTAGTGGGG
CCAGGCTGCATTTAGTGGGGAACATCAATCGCGCTTATTTAAGGGATTACCGCTTAGCCTTGAATGAAAACAGCAAAATG
CTATTAAAAACCCACAACCCCCATTTTAAAAAAGACACGCCCTTTAAAGATTTACAAACTCTGGCTAAAGAGCATGATTT
GATAGATTATTACAATTTAGGGGATGTGGATTTGTTAGACAGAGCGGCTTTAGAAGAAATTTTAGCTCTCAAACCATCGC
TTTTAAGCTTTAGCGCGGATAAATTCTTTAACAGCGCGCAAGCGGGCATTATTATGGGGCAAAAAGAATGGGTTGAAGCG
TTAAAAAACCACCCCCTTTATAGAGCTTTAAGGGTGGGTAAAATCACTCTCACCTTGCTTTTTCACAGCCTAAAAGCATG
GATAAATCATCAAGAAGACATTACAATTCATGCGTTATCAAACCAAACTAAAGACGCATTATTGCAAAAAGCCCTCAAAC
TCTACGCCCTTTTAAAGCCTTTAGAATTGAATGTGAGCATAGCGTCTAGCTTTTCTAAAATAGGGAATTTGCCCGATAGA
GAATTAGAATCCTTTTGCGTGAAAATCCAGCCCAAAAACACCCGCGCTTTAAATGGTGAAAAACTTTATTTAAAGCTTTT
TCAAAAAGGCATTATCGCAAGGATTTCATGCGAATTTGTGTGCTTGGAAGTCTTTAGCCTGAATGAAAAAGATTTTGAAA
AAATCGCTCTAATCTTAGCAGAAATTCTTAATAAAGCTTAA

Upstream 100 bases:

>100_bases
TTAAGGATTTTAAAAAAGTAGTTTTATCAAAAATTTAGCGAGTTTAGTTTAAGATAACGCTTTATTTTAATTCTCAAAAA
GGAATCAAACGCACTCCACT

Downstream 100 bases:

>100_bases
AAATTCGCTATAATAAAATTCCTTTTAAACGCGCCATATCCCCCACAAATAGAGAATGATAGAGAATAAATTTAAAGGAA
CTTAAGAATGGAAAAAATCA

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MAKETLPITPDLLKSPYQKIINASASVFDENHGRSFFSTQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKKLFK
ACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLSSGARLHLVGNINRAYLRDYRLALNENSKM
LLKTHNPHFKKDTPFKDLQTLAKEHDLIDYYNLGDVDLLDRAALEEILALKPSLLSFSADKFFNSAQAGIIMGQKEWVEA
LKNHPLYRALRVGKITLTLLFHSLKAWINHQEDITIHALSNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDR
ELESFCVKIQPKNTRALNGEKLYLKLFQKGIIARISCEFVCLEVFSLNEKDFEKIALILAEILNKA

Sequences:

>Translated_386_residues
MAKETLPITPDLLKSPYQKIINASASVFDENHGRSFFSTQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKKLFK
ACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLSSGARLHLVGNINRAYLRDYRLALNENSKM
LLKTHNPHFKKDTPFKDLQTLAKEHDLIDYYNLGDVDLLDRAALEEILALKPSLLSFSADKFFNSAQAGIIMGQKEWVEA
LKNHPLYRALRVGKITLTLLFHSLKAWINHQEDITIHALSNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDR
ELESFCVKIQPKNTRALNGEKLYLKLFQKGIIARISCEFVCLEVFSLNEKDFEKIALILAEILNKA
>Mature_385_residues
AKETLPITPDLLKSPYQKIINASASVFDENHGRSFFSTQFYETIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKKLFKA
CFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVGGDFNLKDILLSSGARLHLVGNINRAYLRDYRLALNENSKML
LKTHNPHFKKDTPFKDLQTLAKEHDLIDYYNLGDVDLLDRAALEEILALKPSLLSFSADKFFNSAQAGIIMGQKEWVEAL
KNHPLYRALRVGKITLTLLFHSLKAWINHQEDITIHALSNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLPDRE
LESFCVKIQPKNTRALNGEKLYLKLFQKGIIARISCEFVCLEVFSLNEKDFEKIALILAEILNKA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=352, Percent_Identity=33.2386363636364, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 43761; Mature: 43630

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKETLPITPDLLKSPYQKIINASASVFDENHGRSFFSTQFYETIEPYLKEVLTHPIDLE
CCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
CDLNTAKKKNRLTPLKKLFKACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVG
ECCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHEEHHHHHC
GDFNLKDILLSSGARLHLVGNINRAYLRDYRLALNENSKMLLKTHNPHFKKDTPFKDLQT
CCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHH
LAKEHDLIDYYNLGDVDLLDRAALEEILALKPSLLSFSADKFFNSAQAGIIMGQKEWVEA
HHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCHHHHHH
LKNHPLYRALRVGKITLTLLFHSLKAWINHQEDITIHALSNQTKDALLQKALKLYALLKP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
LELNVSIASSFSKIGNLPDRELESFCVKIQPKNTRALNGEKLYLKLFQKGIIARISCEFV
CEECHHHHHHHHHHCCCCHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCHHHHEEHHEE
CLEVFSLNEKDFEKIALILAEILNKA
EEEHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKETLPITPDLLKSPYQKIINASASVFDENHGRSFFSTQFYETIEPYLKEVLTHPIDLE
CCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
CDLNTAKKKNRLTPLKKLFKACFNTEEILIVNNNTSAIFLIANALAQEKEIVVSYGELVG
ECCCHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHEEHHHHHC
GDFNLKDILLSSGARLHLVGNINRAYLRDYRLALNENSKMLLKTHNPHFKKDTPFKDLQT
CCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCHHHHHH
LAKEHDLIDYYNLGDVDLLDRAALEEILALKPSLLSFSADKFFNSAQAGIIMGQKEWVEA
HHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCHHHHHH
LKNHPLYRALRVGKITLTLLFHSLKAWINHQEDITIHALSNQTKDALLQKALKLYALLKP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
LELNVSIASSFSKIGNLPDRELESFCVKIQPKNTRALNGEKLYLKLFQKGIIARISCEFV
CEECHHHHHHHHHHCCCCHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCHHHHEEHHEE
CLEVFSLNEKDFEKIALILAEILNKA
EEEHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA