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The map label for this gene is yhdT [H]

Identifier: 188528261

GI number: 188528261

Start: 1482536

End: 1483885

Strand: Reverse

Name: yhdT [H]

Synonym: HPSH_07635

Alternate gene names: 188528261

Gene position: 1483885-1482536 (Counterclockwise)

Preceding gene: 188528262

Following gene: 188528260

Centisome position: 92.25

GC content: 42.74

Gene sequence:

>1350_bases
ATGGGGAGGAATCAAGGAGCTTATTTGGATCCGTCTGAATCAATTCTGATGTTGATGGTTGCTTTTTTATTGGTGCTGTT
GAACGCTTTTTTTGTGCTTTCAGAGTTTGCCCTTGTGAAAGTGCGTAAAACCCGCTTAGAAGAGCTGGTTAAAATCGGTA
ATTCCAACGCTAAACTCGCTTTAAAGATGAGTCAAAGACTAGACACTTATTTGAGCGCAACGCAGTTAGGCATCACCCTT
TCTTCATTAGCTTTAGGCTGGGTGGGTGAGCCCGCTATCGCAAAATTGTTAGCCGCGCTGTTTGAATCTATGGATTTGAG
AGAAAATCCTATTTTCATCCATTCAATGAGCGTGGTTATAGCGTTTTTAAGCATCACTTTTTTGCATGTCGTGCTGGGCG
AGATTGTGCCTAAATCTTTAGCGATCGCTAAATCTGAAAAAGCCGCTCTTTTTGCCGCGCGCCCCTTGCATGTGTTTTGG
GTCGTGTTTTATCCGGTGGTGCGCCTATTTGATGTGATCGCTCATTTCTTTTTAAAAAAAGTGGGCATCAATCCTAAAGA
GCATGACGGCACGCATTCTGAAGAAGAGTTAAAGATCATTGTGGGCGAGAGTTTGAGAGAGGGTATTATTGATTCAGTGG
AGGGCGAAATCATTAAAAACGCAGTGGATTTTTCTGACACGAGCGCTAAAGAAATCATGACCCCACGAAAAGACATGGTG
TGTTTGGACGAAGAAAACAGCTATGAAGAAAATATAGACATTGTTTTAAAAAGCCGCTTCACGCGCTACCCCTATTGTAA
GGGTTCTAAGGATAACATTATCGGCATGGTGCATATTAAGGACTTGCTTTCTCGCTCTATTTTTACCCCTAAAATGCATG
ATTTCAAGCAAATCGTTAGGAAAATGATCATCGTCCCCGAAAGCGCTTCCATTTCTCAAATCCTTATTAAAATGAAAAAA
GAGCAGATCCATACCGCTTTGGTGATTGATGAATACGGCGGCACAGCCGGGTTGCTCACTATGGAAGATATTATTGAAGA
GATCATGGGCGAGATTAGCGACGAATACGACTTAAAGCAAGAGGGCGTGAACAAGCTTGAAGAGGGCGTGTTTGAATTAG
AGGGCATGCTGGATTTAGAGAGCGTAGAAGAAGTGCTCCACATTGAATTTGACAAAGAATGCGAGCAGGTAACGCTTGGA
GGCTATGTTTTTAGCTTGTTAGAACGCATGCCTATGGAGGGCGATATAATCATTTCGCATGGGTATTTGTTTGAGGTGTT
GAGCGTGGATGGGGCTAGGATAAAACGCTTAAAAGCGAGCAAAAAAGATCAGGGAGAAAACAAAGCATGA

Upstream 100 bases:

>100_bases
AGGGTTTTTAAAGGCTTGATTTTTAAAGTTAGGCTTAATCTTTTATGTTAAAATTCTAAGATTTTATATTTATTTTATAT
TTATCGTTAGGTTTAAAGTC

Downstream 100 bases:

>100_bases
AAAAAACAACCCTCTTTGTATTGAGCTTGTTATTCATTAGCTCTTTGAACGCTGTTGATGGAGTTTCTAAAACCGATCTT
TCTTCTTTGAGCATGGCTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MGRNQGAYLDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALKMSQRLDTYLSATQLGITL
SSLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVIAFLSITFLHVVLGEIVPKSLAIAKSEKAALFAARPLHVFW
VVFYPVVRLFDVIAHFFLKKVGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMV
CLDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIKDLLSRSIFTPKMHDFKQIVRKMIIVPESASISQILIKMKK
EQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLG
GYVFSLLERMPMEGDIIISHGYLFEVLSVDGARIKRLKASKKDQGENKA

Sequences:

>Translated_449_residues
MGRNQGAYLDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALKMSQRLDTYLSATQLGITL
SSLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVIAFLSITFLHVVLGEIVPKSLAIAKSEKAALFAARPLHVFW
VVFYPVVRLFDVIAHFFLKKVGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMV
CLDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIKDLLSRSIFTPKMHDFKQIVRKMIIVPESASISQILIKMKK
EQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLG
GYVFSLLERMPMEGDIIISHGYLFEVLSVDGARIKRLKASKKDQGENKA
>Mature_448_residues
GRNQGAYLDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALKMSQRLDTYLSATQLGITLS
SLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVIAFLSITFLHVVLGEIVPKSLAIAKSEKAALFAARPLHVFWV
VFYPVVRLFDVIAHFFLKKVGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVC
LDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIKDLLSRSIFTPKMHDFKQIVRKMIIVPESASISQILIKMKKE
QIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGG
YVFSLLERMPMEGDIIISHGYLFEVLSVDGARIKRLKASKKDQGENKA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=387, Percent_Identity=41.343669250646, Blast_Score=295, Evalue=8e-80,
Organism=Escherichia coli, GI1790664, Length=432, Percent_Identity=25.9259259259259, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=30.6451612903226, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=24.8192771084337, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082033, Length=235, Percent_Identity=23.8297872340426, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788119, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=250, Percent_Identity=26.8, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50450; Mature: 50318

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRNQGAYLDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LKMSQRLDTYLSATQLGITLSSLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVI
EEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
AFLSITFLHVVLGEIVPKSLAIAKSEKAALFAARPLHVFWVVFYPVVRLFDVIAHFFLKK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMV
HCCCCCCCCCCCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEE
CLDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIKDLLSRSIFTPKMHDFKQIVR
EECCCCCCCCCHHHHEEHHCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHH
KMIIVPESASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQ
HHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
EGVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGGYVFSLLERMPMEGDIIISH
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEC
GYLFEVLSVDGARIKRLKASKKDQGENKA
CHHHHHHHCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GRNQGAYLDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LKMSQRLDTYLSATQLGITLSSLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVI
EEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
AFLSITFLHVVLGEIVPKSLAIAKSEKAALFAARPLHVFWVVFYPVVRLFDVIAHFFLKK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMV
HCCCCCCCCCCCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEE
CLDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIKDLLSRSIFTPKMHDFKQIVR
EECCCCCCCCCHHHHEEHHCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHH
KMIIVPESASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQ
HHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
EGVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGGYVFSLLERMPMEGDIIISH
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEC
GYLFEVLSVDGARIKRLKASKKDQGENKA
CHHHHHHHCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]