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The map label for this gene is pitB [C]

Identifier: 188528262

GI number: 188528262

Start: 1483984

End: 1485585

Strand: Reverse

Name: pitB [C]

Synonym: HPSH_07640

Alternate gene names: 188528262

Gene position: 1485585-1483984 (Counterclockwise)

Preceding gene: 188528271

Following gene: 188528261

Centisome position: 92.36

GC content: 43.26

Gene sequence:

>1602_bases
ATGGAAATTAAAAACATCAAGGAGTTTGAAAAAGCTTCTAAAAAACTCCAAAAAGACACTTTAAAGATCGCTCTCGCTCT
TTTGTTTCTCATTGGCGTTGCTTTACTCGCTCTTATTTTTGGGCAGGCTAATTCTAAGGGATTGTTGCTCACTTTTGCGG
CTGTGATTGGGGGGTATATGGCGATGAATATTGGTGCGAATGATGTGTCCAATAATGTCGGCCCTGCCGTAGGATCTAAA
GCCATTAGCATGGGCGGGGCGATTTTGATTGCTGGGGTTTGTGAAATGCTTGGAGCGATCATTGCTGGGGGGGAAGTGGT
TTCTACGATTAAGGGTCGTATCGTTTCGCCTGAATCCATTAATGATGCGCATGTTTTCATCAATGTCATGTTGGCTAGCC
TTTTGAGTGGGGCATTGTGGTTGCATGTAGCCACTTTAATTGGCGCTCCTGTTTCCACTTCACACTCTGTGGTGGGGGGG
ATTATGGGGGCTGGAATGGCAGCAGCTGGAATGTCTGCTGTCAATTGGCATTTTTTATCAGGTATTGTGGCCAGTTGGGT
GGTTTCGCCTTTAATGGGGGCTTTGATAGCCATGTTTTTTTTAATGCTCATTAAAAAGACTATCGCTTATAAAGAAGATA
AAAAGAGCGCGGCTTTAAAGGTCGTGCCTTACTTGGTAGCGTTGATGAGTTTATCGTTTAGTTGGTATTTGATCGTTAAG
GTTTTAAAACGCCTCTATGCGCTGAATTTTGAAATCCAACTGGCTTGCGGCTGTATCCTTGCGCTTTTAATCTTTATCCT
TTTTAAAAGGTTTGTGTTAAAGAAAGCCCCACAATTAGAAAATAGCCATGAAAGCATTAATGAGCTTTTCAATATCCCTT
TGATTTTTGCCGCTGCGCTTTTAAGCTTTGCGCATGGGGCTAATGATGTGGCTAACGCTATAGGCCCACTAGCGGCCATC
AGTCAAACTTTAGAAGATGCAAATAGCCCTATGGGGAATACCTTAAGCTCTGTGCCGTTGTGGATTATGGTAGTGGGGGC
AGCTGGGATTGCTTTAGGCTTGAGTTTGTATGGGCCAAAGCTCATTAAAACGGTGGGGTCTGAAATCACAGAATTAGACA
AAATGCAAGCTTTTTGCATCGCGCTTTCTGCGGTTATCACCGTGCTTTTAGCCTCTCAATTAGGCTTGCCCGTGAGCTCT
ACGCATATTGTGGTGGGCGCGGTGTTTGGGGTGGGCTTTTTAAGGGAGCGCTTAAGAGAGCAATCAAGAAGGCGTTTTGC
TAGGATCAGAGACAACATTGTAGCGGCGCACTTTGGGGAAGATTTAGAAGAAATTGAAGGCTTTTTAGAGCGCTTTGATA
AAGCCAACTTGAAAGAAAAATCGCTCATGCTAGAGAGCTTGAAAAAAAGCAAGAACACCGCCATCGCTTTGGAATTGAAA
AAGAAAGAAAAAAAGTCGCTTAAAAAAGTGTATAAAGAAGAAGTGATCAAACGCTCCATTTTAAAAAAGATTGTTACCGC
TTGGCTTGTAACCGTGCCGGTTTCTGCGCTTTTAGGGGCGATTCTTTTTGTGGCTCTTGGTTTTATAGAAAAGTATTTCT
AG

Upstream 100 bases:

>100_bases
ATATAATGAGCCATTTTTATCAAACAACGCTTTTTAAGAGTGGCTCAAGGGCTAATTGGATAGAATAAAACCACTATTAG
AATAAGGTTTTTATGACGGT

Downstream 100 bases:

>100_bases
GGTTTTTAAAGGCTTGATTTTTAAAGTTAGGCTTAATCTTTTATGTTAAAATTCTAAGATTTTATATTTATTTTATATTT
ATCGTTAGGTTTAAAGTCAT

Product: phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGVALLALIFGQANSKGLLLTFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMSAVNWHFLSGIVASWVVSPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLSFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNIPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPMGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGAILFVALGFIEKYF

Sequences:

>Translated_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGVALLALIFGQANSKGLLLTFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMSAVNWHFLSGIVASWVVSPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLSFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNIPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPMGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGAILFVALGFIEKYF
>Mature_533_residues
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGVALLALIFGQANSKGLLLTFAAVIGGYMAMNIGANDVSNNVGPAVGSK
AISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRIVSPESINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGG
IMGAGMAAAGMSAVNWHFLSGIVASWVVSPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLSFSWYLIVK
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNIPLIFAAALLSFAHGANDVANAIGPLAAI
SQTLEDANSPMGNTLSSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSS
THIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGAILFVALGFIEKYF

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=140, Percent_Identity=38.5714285714286, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI5803173, Length=132, Percent_Identity=38.6363636363636, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71981576, Length=410, Percent_Identity=32.1951219512195, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17539280, Length=475, Percent_Identity=26.1052631578947, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17557328, Length=482, Percent_Identity=25.103734439834, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25146401, Length=149, Percent_Identity=38.255033557047, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32566716, Length=180, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536725, Length=148, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319773, Length=134, Percent_Identity=38.0597014925373, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356511, Length=247, Percent_Identity=31.1740890688259, Blast_Score=105, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 57183; Mature: 57183

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGVALLALIFGQANSKGLLLTFAAVIGGYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRIVSPESI
HEECCCHHHCCCCCCHHCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
NDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMSAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
GIVASWVVSPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLSFSWYLIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNIPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPMGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGAILFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIKNIKEFEKASKKLQKDTLKIALALLFLIGVALLALIFGQANSKGLLLTFAAVIGGYM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AMNIGANDVSNNVGPAVGSKAISMGGAILIAGVCEMLGAIIAGGEVVSTIKGRIVSPESI
HEECCCHHHCCCCCCHHCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
NDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMSAVNWHFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
GIVASWVVSPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLSFSWYLIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRLYALNFEIQLACGCILALLIFILFKRFVLKKAPQLENSHESINELFNIPLIFAAAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
LSFAHGANDVANAIGPLAAISQTLEDANSPMGNTLSSVPLWIMVVGAAGIALGLSLYGPK
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
LIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEH
KKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGAILFVALGFIEKYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]