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The map label for this gene is murB

Identifier: 188528183

GI number: 188528183

Start: 1410160

End: 1410939

Strand: Reverse

Name: murB

Synonym: HPSH_07235

Alternate gene names: 188528183

Gene position: 1410939-1410160 (Counterclockwise)

Preceding gene: 188528184

Following gene: 188528179

Centisome position: 87.72

GC content: 40.64

Gene sequence:

>780_bases
ATGCTAGAAACCATTATTGATTTTTCTCGTTACAGCAGCGTGAAAATCGGTGCGCCTTTGAAAGTGAGCGTTTTAGAAAA
CGATAATGAAATTTCTCAAGAACACCAGATTATAGGTTTAGCGAACAACCTTTTAATCGCTCCTGGCGCGAAAAATCTCG
CTTTATTGGGCAAGAATTACGATTACATTTGCGATAAGGGTGAGTGGGTGGAGGTAGGGGGAGCGGCCAACTCGTCTAAA
ATTTTTAATTATTTTAGGGCGAATGATTTAGGGGGTTTGGAGTTTTTAGGGCAATTGCCTGGCACTTTGGGGGCGTTAGT
TAAAATGAATGCTGGCATGAAAGAATTTGAAATAAAAAATATTTTAGAAAGCGCTTGTGTTAATAACCAATGGCTAGAAA
ATGAAGCGCTAGGGTTAGATTATCGCAGCAGCCAATTTAATGGCGTTGTTTTAAAAGCGAGGTTTAAAAAAACGCATGGC
TTTAGAGAAGAGGTTTTAAAAGCGTGTAAAAGCATGCGCAAAAGCCACCCCAAATTGCCTAATTTTGGGAGCTGTTTCAA
AAACCCGCCTAACGATTATGCAGGCAGGCTTTTAGAGGGCGTGGGCTTAAGGGGGTATCGCTTAAAAAGAGTGGGCTTTG
CCAAAGAGCATGCGAATTTTTTGGTGAATTTGGGGGGTGCAGAATTTGAAGAAGCGTTGGAATTAATAGAACTCGCCAAA
ACCAGAGTGTTACAAGAATACGGCATTCATTTAGAAGAAGAAGTGAAGATTTTAAGGTAG

Upstream 100 bases:

>100_bases
GATTGGGGTGCTGATTTTAACCATGCCGTGGATGACTAACATGCTTTTAGACTACACCAAAACCTTAATCAAGCTCATTC
CTAAAATCATAGGCTAGAAA

Downstream 100 bases:

>100_bases
GGTTGGAAAGCTTTATTTGAGATTAAGCTTACCCCTAATTATTATTTCGTCTTATCATAATCCATGCTGTTATCACAAAC
GATCCTTTTTCTTTGGGCGT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLETIIDFSRYSSVKIGAPLKVSVLENDNEISQEHQIIGLANNLLIAPGAKNLALLGKNYDYICDKGEWVEVGGAANSSK
IFNYFRANDLGGLEFLGQLPGTLGALVKMNAGMKEFEIKNILESACVNNQWLENEALGLDYRSSQFNGVVLKARFKKTHG
FREEVLKACKSMRKSHPKLPNFGSCFKNPPNDYAGRLLEGVGLRGYRLKRVGFAKEHANFLVNLGGAEFEEALELIELAK
TRVLQEYGIHLEEEVKILR

Sequences:

>Translated_259_residues
MLETIIDFSRYSSVKIGAPLKVSVLENDNEISQEHQIIGLANNLLIAPGAKNLALLGKNYDYICDKGEWVEVGGAANSSK
IFNYFRANDLGGLEFLGQLPGTLGALVKMNAGMKEFEIKNILESACVNNQWLENEALGLDYRSSQFNGVVLKARFKKTHG
FREEVLKACKSMRKSHPKLPNFGSCFKNPPNDYAGRLLEGVGLRGYRLKRVGFAKEHANFLVNLGGAEFEEALELIELAK
TRVLQEYGIHLEEEVKILR
>Mature_259_residues
MLETIIDFSRYSSVKIGAPLKVSVLENDNEISQEHQIIGLANNLLIAPGAKNLALLGKNYDYICDKGEWVEVGGAANSSK
IFNYFRANDLGGLEFLGQLPGTLGALVKMNAGMKEFEIKNILESACVNNQWLENEALGLDYRSSQFNGVVLKARFKKTHG
FREEVLKACKSMRKSHPKLPNFGSCFKNPPNDYAGRLLEGVGLRGYRLKRVGFAKEHANFLVNLGGAEFEEALELIELAK
TRVLQEYGIHLEEEVKILR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the murB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR003170
- InterPro:   IPR011601 [H]

Pfam domain/function: PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 28866; Mature: 28866

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETIIDFSRYSSVKIGAPLKVSVLENDNEISQEHQIIGLANNLLIAPGAKNLALLGKNY
CCCHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHEEEEECCEEECCCCCCEEEECCCC
DYICDKGEWVEVGGAANSSKIFNYFRANDLGGLEFLGQLPGTLGALVKMNAGMKEFEIKN
CEEECCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
ILESACVNNQWLENEALGLDYRSSQFNGVVLKARFKKTHGFREEVLKACKSMRKSHPKLP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCC
NFGSCFKNPPNDYAGRLLEGVGLRGYRLKRVGFAKEHANFLVNLGGAEFEEALELIELAK
CCCHHHCCCCHHHHHHHHHHCCCCCEEEHHCCCHHHHCCEEEECCCCCHHHHHHHHHHHH
TRVLQEYGIHLEEEVKILR
HHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MLETIIDFSRYSSVKIGAPLKVSVLENDNEISQEHQIIGLANNLLIAPGAKNLALLGKNY
CCCHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHEEEEECCEEECCCCCCEEEECCCC
DYICDKGEWVEVGGAANSSKIFNYFRANDLGGLEFLGQLPGTLGALVKMNAGMKEFEIKN
CEEECCCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
ILESACVNNQWLENEALGLDYRSSQFNGVVLKARFKKTHGFREEVLKACKSMRKSHPKLP
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCC
NFGSCFKNPPNDYAGRLLEGVGLRGYRLKRVGFAKEHANFLVNLGGAEFEEALELIELAK
CCCHHHCCCCHHHHHHHHHHCCCCCEEEHHCCCHHHHCCEEEECCCCCHHHHHHHHHHHH
TRVLQEYGIHLEEEVKILR
HHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]