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The map label for this gene is trpD

Identifier: 188528069

GI number: 188528069

Start: 1305149

End: 1306156

Strand: Reverse

Name: trpD

Synonym: HPSH_06630

Alternate gene names: 188528069

Gene position: 1306156-1305149 (Counterclockwise)

Preceding gene: 188528070

Following gene: 188528068

Centisome position: 81.2

GC content: 41.07

Gene sequence:

>1008_bases
ATGAAAGAGATTTTAAACGCTCTATACCATCAAAAAGACTTAAACGATGGAGAAGTTAAAAAATTATTTACCCTTATTAT
CAACGAAAAAGTAAGCCCGGCGCAACTTGGGGCGGTTTTGTGCGCTTTAAAAATCAAGGGCGAGAGCTTTAAGGAAATTA
GCGTTGCTGCAACCACGCTTTTAGAGCACGCCCCTAAGCCTTTTGATAGCGGCTTGGATTTGATAGACAATTGCGGCACA
GGGGGCGATGGGTTAAAAACGATTAACATCAGCACGATTGCCGCGCTCATTGCCAGCTCTATGGGATTGTCTATGGCCAA
ACACGGATCAAGGAGCGTTTCTAGTCATAGCGGGAGTGCGGATTTGTTGGAAAATTTAGGCGTGAACATTGAAATGAATC
CCACGCAATTAGAGAATTGTTTCAAACAAACGCATTTTGGGTTTTTATTCGCGCCTTTATACCATCAAAGTTTTAAAAAA
TCCGCCCCTTTAAGAAAAGAGCTTTTCACTAAAACGATTTTTAATTGCTTAGGGCCTTTAATCAACCCCTTAAGGCCCAA
AATCCAGCTTTTAGGCGTGTATGAAAAATCCTTGTGCAAGACTATGGCGCTAGCATTAAAGGCTTTAGGCGTTAAAAGGG
CGATGGTGGTTAATGGAGGGGGGACGGATGAAATCGTGTTGCACGATACTACGCATGCGTGTGAATTGAAAAATAACGGA
ATTTTAGAGTATGACTTGAGCGCTAAAGATTTTGATTTGCCCCCCTATGATTTGAAAGAATTACAGATTAAAAACGCGCA
AGAAAGCGTTCAAGCGTGTTTGGATATTTTAGAAAACAAAGGCAAGGATTCGCATACAATGGTGGTTGTGGCGAATGTGG
CGAGTTTGTTGTATTTAAGCCATAAGGCTAAAGATTTAAAAGAGGGCGTGGGCATGACTTTAGAGCATTTAAAAACCAAA
GTGCCTTATACGCATTTGCAAAAAATCATAAGATTAAGCCATGCCTAG

Upstream 100 bases:

>100_bases
AAGACAAGATTTTAGCCTATCAATTCCACCCTGAAAGCATCATGACTTTACAAGGGAGGGCGTTGTTAGAGCAAAGCGTG
GGGTTTTTAGAAGGGTTATT

Downstream 100 bases:

>100_bases
CGTGTTAGAAAACATCCTTAAAGACAAGCTCCTAGAAGTTTCTGTGCTTAAAAAAAATCACGCTTTACCGACAAACATAA
ACCCAAGCGATAGGGATTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFDSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVGMTLEHLKTK
VPYTHLQKIIRLSHA

Sequences:

>Translated_335_residues
MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFDSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVGMTLEHLKTK
VPYTHLQKIIRLSHA
>Mature_335_residues
MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFDSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNG
ILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVGMTLEHLKTK
VPYTHLQKIIRLSHA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=324, Percent_Identity=41.358024691358, Blast_Score=222, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=337, Percent_Identity=28.7833827893175, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36601; Mature: 36601

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTL
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LEHAPKPFDSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSA
HHHCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCH
DLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNG
HCCCCCHHHEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEEECCCC
ILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
HKAKDLKEGVGMTLEHLKTKVPYTHLQKIIRLSHA
HHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTL
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHH
LEHAPKPFDSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSA
HHHCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCH
DLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNG
HCCCCCHHHEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEEECCCC
ILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
HKAKDLKEGVGMTLEHLKTKVPYTHLQKIIRLSHA
HHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA