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The map label for this gene is nuoN [H]

Identifier: 188528062

GI number: 188528062

Start: 1295923

End: 1297401

Strand: Direct

Name: nuoN [H]

Synonym: HPSH_06595

Alternate gene names: 188528062

Gene position: 1295923-1297401 (Clockwise)

Preceding gene: 188528061

Following gene: 188528063

Centisome position: 80.56

GC content: 43.27

Gene sequence:

>1479_bases
ATGTTAATAGATAGTCTCCACATCTCTTTTGACAGCTTTAATTTTGAGAGCATTTTACCCATGCTGGTGTTGGTGTGTGG
GGGGATTTCCACGCTCTTAATCAACGCTTTCACTTCCAGGTTTTCACGCAACTTGAATGTGTTTTTATGCATGCTCTTTT
TGGTTTTGGATTTTTTGGTGGTTTTAGGATTACAAGAGCAAGAAAACGCCTTTTTTGGGTTTTTGAGCTTGGATACTCTC
TCGCTCGTTTCTCAAAGCATTGTCTTGATTTCAGCCTTCTTGCTCATTTTCTTAGCCCTTTCAAAAGAGCGCTTCAACGA
ATTTCAAACCGCTGAATTTTATTCCCTATACTTGTTTATTGTCGCTGGCTTTCAGTTCATGGTTTCAAGCAACCATTTAT
TATTAATCCTTATCGGGCTAGAAACAGCGTCCTTACCCCTTTGTGTGTTAATGGCGTTGAGCGATAAACGCTACGGATTA
GAAGCAGGGATCAAATATTTCACTATGGGGGCGATGGCGAGCGCGTTTTTTGCTATGGGGGCGATGGCTTTCTATCTCCT
CACAGGGAGCTTGAATCTTGAAGTCATTACCCTATACTTACACACTGAAGGTATCACAAACCCCATGCTCTTTGCGATGG
GCGCTATCTTTTTGATTGGAGCGATTGGCTTTAAGGTTTCTTTAGTGCCTTTCCATACCTGGATGCCTGATGTGTATGAG
GGCAATAATCCGGTCTTTGCGAGCTATATTTCCATTGTGCCTAAAATCGCTGGCTTTGTGGTAGCGACTCGCCTTTTTGG
AGCGTTTATAGACACTCGCACCGCTTGGGTAGAAGACATTTTTTACGCCCTCATTCTTATGACTATCACCATCCCTAATT
TCCTTGCTTTATGGCAAGAAGATGTCAAAAGAATGCTCGCTTATAGCTCCATTTCGCATTCTGGGTTCGCTTTAGCATGC
GTGTTTATCCACACTCAAGACAGCCAACAAGCGATGTTTGTTTATTGGTTCATGTTCGCCTTCACTTACATTGGGGCTTT
TGGCCTTTTATGGCTCTTAAAAAGCCGGGAAAAAACATGGGATGAACGCTACGATCACCCCTATTCTAAATTCAACGGCC
TTATCAAAACCCACCCTTTAGTGGCGATCTTGGGCGCTATTTTTGTTTTTGGGCTTACAGGGATCCCGCCTTTTAGCGTG
TTTTGGGGGAAATTTTTGGCCGTTGAAAGCGCTTTAGAGAGCAATCACATTCTTTTAGCGGTGGTGATGTTAGTTAATAG
CGCAGTGGCTGCGTTTTATTATTTCCGTTGGCTCGTGGCGATGTTTTTCAATAAGCCCTTACAAGCCCAAAGCTACGCTC
AAAACGATATTTACACCCAAAACGCTACCATGCCCATTTATGCGGTCGTTATTGCCATGGCGTTAGCGTGCTTGTTCTCT
GTTTTTATGATGCGAGGGCTTTTAGAGTTTGTGGCTTAA

Upstream 100 bases:

>100_bases
AAACCGATTGAGCAAGGCTCTAGGCAGCTTTTAGAGGTGATAGAAATCCGCTCGCTCCCTTTTTTAGGTTCATTGGATAC
TAAGATAAAAGAGGTTTCTT

Downstream 100 bases:

>100_bases
GTCAAAAATCTTTCTTTTAATGGGTGTGAGTTTGCTCTCCCATTCTCTCAACGCTTTAAGCCTCACGCTCACGCAAGGCA
AGGAAGGGGGGGAGGATTTT

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGISTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLQEQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRTAWVEDIFYALILMTITIPNFLALWQEDVKRMLAYSSISHSGFALAC
VFIHTQDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLTGIPPFSV
FWGKFLAVESALESNHILLAVVMLVNSAVAAFYYFRWLVAMFFNKPLQAQSYAQNDIYTQNATMPIYAVVIAMALACLFS
VFMMRGLLEFVA

Sequences:

>Translated_492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGISTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLQEQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRTAWVEDIFYALILMTITIPNFLALWQEDVKRMLAYSSISHSGFALAC
VFIHTQDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLTGIPPFSV
FWGKFLAVESALESNHILLAVVMLVNSAVAAFYYFRWLVAMFFNKPLQAQSYAQNDIYTQNATMPIYAVVIAMALACLFS
VFMMRGLLEFVA
>Mature_492_residues
MLIDSLHISFDSFNFESILPMLVLVCGGISTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLQEQENAFFGFLSLDTL
SLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRTAWVEDIFYALILMTITIPNFLALWQEDVKRMLAYSSISHSGFALAC
VFIHTQDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLTGIPPFSV
FWGKFLAVESALESNHILLAVVMLVNSAVAAFYYFRWLVAMFFNKPLQAQSYAQNDIYTQNATMPIYAVVIAMALACLFS
VFMMRGLLEFVA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=357, Percent_Identity=32.2128851540616, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788831, Length=376, Percent_Identity=24.2021276595745, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788614, Length=387, Percent_Identity=28.4237726098191, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55290; Mature: 55290

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSLHISFDSFNFESILPMLVLVCGGISTLLINAFTSRFSRNLNVFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLQEQENAFFGFLSLDTLSLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYSLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRTAWVEDIFYALILMTITIPNFLALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTQDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFNGLIKTHPLVAILGAIFVFGLTGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
VVMLVNSAVAAFYYFRWLVAMFFNKPLQAQSYAQNDIYTQNATMPIYAVVIAMALACLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
VFMMRGLLEFVA
HHHHHHHHHHHC
>Mature Secondary Structure
MLIDSLHISFDSFNFESILPMLVLVCGGISTLLINAFTSRFSRNLNVFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLQEQENAFFGFLSLDTLSLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYSLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRTAWVEDIFYALILMTITIPNFLALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTQDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFNGLIKTHPLVAILGAIFVFGLTGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
VVMLVNSAVAAFYYFRWLVAMFFNKPLQAQSYAQNDIYTQNATMPIYAVVIAMALACLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
VFMMRGLLEFVA
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA