Click here to switch to the map view.

The map label for this gene is frr

Identifier: 188528045

GI number: 188528045

Start: 1280991

End: 1281548

Strand: Direct

Name: frr

Synonym: HPSH_06510

Alternate gene names: 188528045

Gene position: 1280991-1281548 (Clockwise)

Preceding gene: 188528044

Following gene: 188528046

Centisome position: 79.64

GC content: 39.25

Gene sequence:

>558_bases
ATGTTACAAGCCATTTATAACGAAACCAAAGATCTAATGCAAAAAAGCATTCAGGCTTTAAATAGGGATTTTTCCACTCT
AAGGAGCGCGAAAGTTTCAGTCAATATTTTAGATCACATCAAAGTGGATTATTACGGCACGCCCACCACATTAAATCAAG
TCGGATCCGTGATGAGCTTAGATGCGACCACTCTTCAAATCAGCCCGTGGGAAAAAAACCTGCTCAAAGAAATTGAAAGA
TCCATTCAAGAAGCCAATATCGGCGTGAATCCTAATAACGACGGCGAAACGATCAAGCTTTTTTTCCCGCCCATGACAAC
CGAGCAAAGAAAACTCATCGCAAAAGACGCCAAAGCGATGGGTGAAAAGGCTAAAGTGGCTGTAAGAAATATCCGCCAAG
ACGCTAACAATAAGATAAAAAAATTAGAAAAAGACAAAGAAATCAGCGAAGATGAAAGCAAAAAAGCCCAAGAGCAGATC
CAAAAAATCACCGATGAAGCCATTAAAACAATTGATGAAAGCGTGAAAAACAAAGAAGACGCGATTTTAAAGGTTTAA

Upstream 100 bases:

>100_bases
AAACCAAAGAGAATACAAAAACGCCCCCAACCGCCCACCAAAAGCCTAAAACGCACACGCAAACCAACGCCCATACAAAC
CAAAAAAAGGATGAAAAATA

Downstream 100 bases:

>100_bases
ACCATGGATATTAAGGCATGTTATCAAAACGCTAAAGCGCTGTTAGAGGGGCATTTCTTGCTCAGCAGTGGGTTTCATTC
TAATTATTATTTGCAATCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQI
QKITDEAIKTIDESVKNKEDAILKV

Sequences:

>Translated_185_residues
MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQI
QKITDEAIKTIDESVKNKEDAILKV
>Mature_185_residues
MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQI
QKITDEAIKTIDESVKNKEDAILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=40.2173913043478, Blast_Score=157, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24661488, Length=172, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20946; Mature: 20946

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEEEEECCCCHHHHHHCCHHCC
DATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQIQKITDEAIKTIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC
>Mature Secondary Structure
MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEEEEECCCCHHHHHHCCHHCC
DATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQIQKITDEAIKTIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA