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The map label for this gene is nlaIIIM [H]

Identifier: 188527996

GI number: 188527996

Start: 1235036

End: 1236025

Strand: Reverse

Name: nlaIIIM [H]

Synonym: HPSH_06255

Alternate gene names: 188527996

Gene position: 1236025-1235036 (Counterclockwise)

Preceding gene: 188527997

Following gene: 188527995

Centisome position: 76.84

GC content: 37.68

Gene sequence:

>990_bases
ATGAATTACATCGGCTCTAAATACAAACTCATTCCCTTTATTAAGGAAAATATCCATGCGGTTGCAGCCAATGATCTCTC
TGGCGTAATTTTTTGTGATCTATTCGCTGGGACGGGCATTGTGGGGCGTGCGTTTAAAAAGGCTGTCCATAAAATCATTT
CTAATGATTTGGAATATTATAGCTTTGTTTTGAATCAAAATTATATCGGCAACATTCAAGAAATCCCCAATAAAGAAGAG
CTTATTGATAGACTCAATAGCGTTGCTTTAAAAAAGGGCTTTATCTATTCGCATTATTCTTTAGGGGGGAGTTCAAGGCA
GTATTTTAGCGAAACAAACGCTCAAAAAATTGATACGATGCGTTTGAAAATTGAAGAGCTTAAGCTTTCTCAAAACATTG
ATAATCATGCGTATTATTTTTTGCTCGCATCGTTATTAGAAAGCGCGGACAAGGTGGCTAACACCGCTTCAGTTTATGGG
GCTTTTTTAAAACGCCTTAAAAAAAGCGCTCAAAAAGAACTCATTTTAAAAGGCGCTGATTTTGATTTGAGTTCAAACGC
TAATGAAGTGTATCAGCAAGACGCTAGCGAACTGATTGAAAAGATTTCAGGGGATATTTTGTATTTAGACCCTCCTTATA
ATGCGAGGCAATATGGGGCGAATTACCATTTATTAAATACGATTGCCGCTTATACGCCCTTTGCTCCAAAAGGCAAAACC
GGCTTGCCCAGTTACCAGAGATCATCGTTTTGCTCTCGCGCTAAAATCTTAAACGCTTTTGAAAATTTAATCAAAACAGC
GCGATTCAAATACATCTTTTTAAGCTATAACAATGAAGGGCTTATGGGTGAAACAGAGATTGGGAATATTTTAAAAAAAT
ACGGCGCTTACTCCTTGATGACCAAAACTTACATGCGTTTTAAAGCGGATAGCAAACGCGCCCACAAAGCCGCACACACC
AAAGAGTGTTTGCATATTCTTATCAAATAA

Upstream 100 bases:

>100_bases
GGGGTTAAGACTTATTCATGATCAAGTTATGTTACAATACATAAAATTTAACTTTAACAATAGCCATACCATTTTCAAAG
AAGCATACAAACACAGATCA

Downstream 100 bases:

>100_bases
GAGTCAAGATAGTTCCAACCTTTAAACGGCAAAAATAATCGCTTAAATATCGCTTGAATAAGGTAAAATGAAGCCAAAAT
AAGCCTATAAAAAAGGGGAA

Product: ulcer associated adenine specific DNA methyltransferase

Products: NA

Alternate protein names: M.NlaIII; Adenine-specific methyltransferase NlaIII [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNYIGSKYKLIPFIKENIHAVAANDLSGVIFCDLFAGTGIVGRAFKKAVHKIISNDLEYYSFVLNQNYIGNIQEIPNKEE
LIDRLNSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDTMRLKIEELKLSQNIDNHAYYFLLASLLESADKVANTASVYG
AFLKRLKKSAQKELILKGADFDLSSNANEVYQQDASELIEKISGDILYLDPPYNARQYGANYHLLNTIAAYTPFAPKGKT
GLPSYQRSSFCSRAKILNAFENLIKTARFKYIFLSYNNEGLMGETEIGNILKKYGAYSLMTKTYMRFKADSKRAHKAAHT
KECLHILIK

Sequences:

>Translated_329_residues
MNYIGSKYKLIPFIKENIHAVAANDLSGVIFCDLFAGTGIVGRAFKKAVHKIISNDLEYYSFVLNQNYIGNIQEIPNKEE
LIDRLNSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDTMRLKIEELKLSQNIDNHAYYFLLASLLESADKVANTASVYG
AFLKRLKKSAQKELILKGADFDLSSNANEVYQQDASELIEKISGDILYLDPPYNARQYGANYHLLNTIAAYTPFAPKGKT
GLPSYQRSSFCSRAKILNAFENLIKTARFKYIFLSYNNEGLMGETEIGNILKKYGAYSLMTKTYMRFKADSKRAHKAAHT
KECLHILIK
>Mature_329_residues
MNYIGSKYKLIPFIKENIHAVAANDLSGVIFCDLFAGTGIVGRAFKKAVHKIISNDLEYYSFVLNQNYIGNIQEIPNKEE
LIDRLNSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDTMRLKIEELKLSQNIDNHAYYFLLASLLESADKVANTASVYG
AFLKRLKKSAQKELILKGADFDLSSNANEVYQQDASELIEKISGDILYLDPPYNARQYGANYHLLNTIAAYTPFAPKGKT
GLPSYQRSSFCSRAKILNAFENLIKTARFKYIFLSYNNEGLMGETEIGNILKKYGAYSLMTKTYMRFKADSKRAHKAAHT
KECLHILIK

Specific function: This methylase recognizes the double-stranded sequence CATG, causes specific methylation on A-2 on both strands and protects the DNA from cleavage by the NlaIII endonuclease [H]

COG id: COG3392

COG function: function code L; Adenine-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 37200; Mature: 37200

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIGSKYKLIPFIKENIHAVAANDLSGVIFCDLFAGTGIVGRAFKKAVHKIISNDLEYY
CCCCCCCEEEHHHHHHCHHEEECCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHCCHHHH
SFVLNQNYIGNIQEIPNKEELIDRLNSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDTM
HHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHCCHHHHHHH
RLKIEELKLSQNIDNHAYYFLLASLLESADKVANTASVYGAFLKRLKKSAQKELILKGAD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
FDLSSNANEVYQQDASELIEKISGDILYLDPPYNARQYGANYHLLNTIAAYTPFAPKGKT
CCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCCCCCC
GLPSYQRSSFCSRAKILNAFENLIKTARFKYIFLSYNNEGLMGETEIGNILKKYGAYSLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
TKTYMRFKADSKRAHKAAHTKECLHILIK
HHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYIGSKYKLIPFIKENIHAVAANDLSGVIFCDLFAGTGIVGRAFKKAVHKIISNDLEYY
CCCCCCCEEEHHHHHHCHHEEECCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHCCHHHH
SFVLNQNYIGNIQEIPNKEELIDRLNSVALKKGFIYSHYSLGGSSRQYFSETNAQKIDTM
HHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHCCHHHHHHH
RLKIEELKLSQNIDNHAYYFLLASLLESADKVANTASVYGAFLKRLKKSAQKELILKGAD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
FDLSSNANEVYQQDASELIEKISGDILYLDPPYNARQYGANYHLLNTIAAYTPFAPKGKT
CCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCHHHHHHHHHHCCCCCCCCC
GLPSYQRSSFCSRAKILNAFENLIKTARFKYIFLSYNNEGLMGETEIGNILKKYGAYSLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHH
TKTYMRFKADSKRAHKAAHTKECLHILIK
HHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2277628 [H]