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The map label for this gene is sotB [H]

Identifier: 188527973

GI number: 188527973

Start: 1206231

End: 1207403

Strand: Reverse

Name: sotB [H]

Synonym: HPSH_06140

Alternate gene names: 188527973

Gene position: 1207403-1206231 (Counterclockwise)

Preceding gene: 188527976

Following gene: 188527972

Centisome position: 75.06

GC content: 43.56

Gene sequence:

>1173_bases
ATGATAACCAAACAATCGTATCAAAAACTCGCCTTAATGCGGGTTTTTGTGTTTTCGCTTTCGGCGTTTATTTTTAACAC
CACGGAGTTTGTCCCTGTCGCGCTCTTATCAGACATTGCGAAAAGTTTTGAAATGGAGAGCGCAACAGTGGGGCTTATGA
TCACTCTTTATGCATGGGTGGTGTCTCTTGGTTCATTGCCCTTGATGCTGCTTAGCGCTAAAATTGAAAGGAAACGCTTA
TTGCTTTTTCTTTTTGCCCTTTTCATTCTCAGTCATATCCTTTCAGCGTTAGCGTGGAATTTTTGGGTGTTACTGATTTC
TCGTATTGGTATCGCTTTTGCCCACTCTATTTTTTGGTCCATTACGGCTTCTTTAGTCATTCGTGTCGCACCCATTGGCA
GGAAACAGCAAGCTTTGGGGTTATTGGCGTTAGGGAGTTCGTTAGCGATGATTTTAGGGTTGCCGCTTGGGAGAATCATT
GGGCAAATTCTAAATTGGCGCTCTACTTTTGGCGTGATTGGTGGCGTTGCGACTCTTATAGCGTTGCTGATGTATAAATT
GCTCCCGCATTTACCCAGCAAAAACGCAGGCACGCTCGCAAGTGTCCCTATATTAATGAAACGACCGCTTTTGGTGGGGA
TTTATTTGCTTGTGATCATGGTTATCTCTGGGCATTTCACCACTTATAGCTATATTGAGCCTTTTATCATTCAAATCAGC
CAATTTTCCCCTGACATTACGACGCTAATGCTGTTTGTGTTTGGGTTAGCGGGCGTGGTGGGGAGTTTTTTATTCGGCCG
TTTGTATGCGAAAAATTCAAGAAAATTTATCGCTTTTGCGATGATTTTAGTCATTTGCCCGCAACTTTTGCTTTTTGTGT
TTAAAAATTCAGAGTGGGTGGTTTTCTTGCAAATTTTCTTATGGGGGATTGGGATCACTTCGCTTGGGATTTCCTTGCAA
ATGAGGGTGTTGCAGCTCGCGCCAGATGCCACGGATGTCGCGAGCGCGATTTTTTCGGGGAGCTATAATGTGGGGATTGG
AGCAGGAGCGCTGTTTGGCAGTATTGTGATCCACCAATTAGGGCTAGGGTATATTGGCTTTGTGGGTGGGGCTTTAGGTT
TGTTGGCGCTGTTTTGGTTTAGATTCATTACGATAAAGTTTAAAAAAACATAA

Upstream 100 bases:

>100_bases
ATTTGTTTTAACCAGCCCCCAATTTATAAGCGATTAAAATTTTTGTCTTATACTATGAGTTTTCAAATTGAATAAAATTT
AACCCTTTAAGATTTAAATG

Downstream 100 bases:

>100_bases
AGAGCGTTAAAAGGATTACCCCAATAAAGAAATCCCTTTTGCGCTAAAAACCATTTTTTAAAATTTAATGATACTGCTTA
AATCTAAGTGCGCTAAAGAT

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MITKQSYQKLALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITLYAWVVSLGSLPLMLLSAKIERKRL
LLFLFALFILSHILSALAWNFWVLLISRIGIAFAHSIFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRII
GQILNWRSTFGVIGGVATLIALLMYKLLPHLPSKNAGTLASVPILMKRPLLVGIYLLVIMVISGHFTTYSYIEPFIIQIS
QFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNSEWVVFLQIFLWGIGITSLGISLQ
MRVLQLAPDATDVASAIFSGSYNVGIGAGALFGSIVIHQLGLGYIGFVGGALGLLALFWFRFITIKFKKT

Sequences:

>Translated_390_residues
MITKQSYQKLALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITLYAWVVSLGSLPLMLLSAKIERKRL
LLFLFALFILSHILSALAWNFWVLLISRIGIAFAHSIFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRII
GQILNWRSTFGVIGGVATLIALLMYKLLPHLPSKNAGTLASVPILMKRPLLVGIYLLVIMVISGHFTTYSYIEPFIIQIS
QFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNSEWVVFLQIFLWGIGITSLGISLQ
MRVLQLAPDATDVASAIFSGSYNVGIGAGALFGSIVIHQLGLGYIGFVGGALGLLALFWFRFITIKFKKT
>Mature_390_residues
MITKQSYQKLALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITLYAWVVSLGSLPLMLLSAKIERKRL
LLFLFALFILSHILSALAWNFWVLLISRIGIAFAHSIFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRII
GQILNWRSTFGVIGGVATLIALLMYKLLPHLPSKNAGTLASVPILMKRPLLVGIYLLVIMVISGHFTTYSYIEPFIIQIS
QFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNSEWVVFLQIFLWGIGITSLGISLQ
MRVLQLAPDATDVASAIFSGSYNVGIGAGALFGSIVIHQLGLGYIGFVGGALGLLALFWFRFITIKFKKT

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=379, Percent_Identity=51.7150395778364, Blast_Score=350, Evalue=6e-98,
Organism=Escherichia coli, GI1787947, Length=342, Percent_Identity=27.7777777777778, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693198, Length=362, Percent_Identity=24.8618784530387, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786595, Length=347, Percent_Identity=26.2247838616715, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42818; Mature: 42818

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKQSYQKLALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITLYAWV
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLISRIGIAFAHSIFWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRIIGQILNWRSTFGVIGGVATLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALLMYKLLPHLPSKNAGTLASVPILMKRPLLVGIYLLVIMVISGHFTTYSYIEPFIIQIS
HHHHHHHHCCCCCCCCCCHHHCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNSEWV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
VFLQIFLWGIGITSLGISLQMRVLQLAPDATDVASAIFSGSYNVGIGAGALFGSIVIHQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GLGYIGFVGGALGLLALFWFRFITIKFKKT
CCHHHHHHHHHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure
MITKQSYQKLALMRVFVFSLSAFIFNTTEFVPVALLSDIAKSFEMESATVGLMITLYAWV
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLGSLPLMLLSAKIERKRLLLFLFALFILSHILSALAWNFWVLLISRIGIAFAHSIFWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRIIGQILNWRSTFGVIGGVATLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALLMYKLLPHLPSKNAGTLASVPILMKRPLLVGIYLLVIMVISGHFTTYSYIEPFIIQIS
HHHHHHHHCCCCCCCCCCHHHCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QFSPDITTLMLFVFGLAGVVGSFLFGRLYAKNSRKFIAFAMILVICPQLLLFVFKNSEWV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
VFLQIFLWGIGITSLGISLQMRVLQLAPDATDVASAIFSGSYNVGIGAGALFGSIVIHQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GLGYIGFVGGALGLLALFWFRFITIKFKKT
CCHHHHHHHHHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA