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The map label for this gene is asd [H]

Identifier: 188527976

GI number: 188527976

Start: 1210706

End: 1211746

Strand: Reverse

Name: asd [H]

Synonym: HPSH_06155

Alternate gene names: 188527976

Gene position: 1211746-1210706 (Counterclockwise)

Preceding gene: 188527977

Following gene: 188527973

Centisome position: 75.33

GC content: 41.88

Gene sequence:

>1041_bases
ATGAAGACTTATAATGTCGCTATTGTTGGGGCTAGTGGGGCGGTAGGCCAAGAGCTGATTAAGGGTTTAGAAAATTCTTC
TTTCCCGATTAAAAAATTTGTCCCGCTCGCTAGTGCTAGGAGTGCCGGTAAAAAGATTAAAGCTTTCCATAAAGACTATG
AGATTTTAGAAACCATGCATGAAGTTTTTGAAAAAGAAAGAATAGACATCGCCTTTTTTAGCGCTGGGGGGAGCGTGAGC
GAAGAATTTGCCACAAGCGCTGCAAAAACTGCCTTAGTGATTGATAACACGAGCTTTTTTAGATTGAATAAAAAAGTGCC
TTTAGTCGTGCCTGAAATCAACGCTAAAGAAATTTTTAACGCTCCTTTAAATATCATCGCTAACCCCAATTGCTCCACCA
TTCAAATGACGCAAATTTTAAACCCCTTACACCTTCATTTTAAGATAAAAAGCGTTATTGTTAGCACCTATCAAGCCGTG
AGTGGGGCAGGGAATAAGGGCATAGAGGGTTTAAAGAATGAGTTAAAAACCGCTTTAGAATGTTTAGAAAAAGACCCCGC
TATTGATTTAAACCAAGTCTTGCAAGCCGGGGTTTTCCCTTACCCGATCGCTTTCAATGCGATCGCTCATATTGATACTT
TTAAGGAGAATGGTTACACGAAAGAAGAGCTAAAAATGGTGCATGAAACCCATAAAATCATGGGCGTGGATTTCCCTATC
AGCGCGACTTGCGTGCGCGTGCCGGTATTGAGGAGTCATAGCGAGAGTTTGAGTATCGCTTTTGAAAAAGAATTCGATCT
TAAAGAAGTCTATGAAGTTTTAAAAAACGCCCCTAGCGTGGTTGTTTGCGATGATCCTAGCCATAATCTCTATCCCACGC
CCTTAAAAGCGAGCAACACGGATAGCGCCTTTATTGGGCGTTTGAGGAAGGATTTGTTTGATAAGAAAACTTTGCATGGC
TTTTGCGTGGCGGATCAATTAAGAGTGGGGGCAGCCACCAATGCGCTCAAAATCGCTCTGCATTACATTAAGAACGCTTG
A

Upstream 100 bases:

>100_bases
GAATTTAAAAGCGAAACCTTAAGCTTGAAAAACATGCATTCAGGCATGCAGTTGAATTGTTTGAGTTTTTTAAAAGCCCT
TGAAATCATTGGAGAAAACG

Downstream 100 bases:

>100_bases
GTTTAGTTTTTAATCAAGCGATAATTCTTTAAAAAGCGTTATTAGAGAGAGTTGCTATAAAAATACCCTTATCCCCTTAA
TGAGTTTTATTAAAAATGAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKTYNVAIVGASGAVGQELIKGLENSSFPIKKFVPLASARSAGKKIKAFHKDYEILETMHEVFEKERIDIAFFSAGGSVS
EEFATSAAKTALVIDNTSFFRLNKKVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIEGLKNELKTALECLEKDPAIDLNQVLQAGVFPYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASNTDSAFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA

Sequences:

>Translated_346_residues
MKTYNVAIVGASGAVGQELIKGLENSSFPIKKFVPLASARSAGKKIKAFHKDYEILETMHEVFEKERIDIAFFSAGGSVS
EEFATSAAKTALVIDNTSFFRLNKKVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIEGLKNELKTALECLEKDPAIDLNQVLQAGVFPYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASNTDSAFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA
>Mature_346_residues
MKTYNVAIVGASGAVGQELIKGLENSSFPIKKFVPLASARSAGKKIKAFHKDYEILETMHEVFEKERIDIAFFSAGGSVS
EEFATSAAKTALVIDNTSFFRLNKKVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAV
SGAGNKGIEGLKNELKTALECLEKDPAIDLNQVLQAGVFPYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASNTDSAFIGRLRKDLFDKKTLHG
FCVADQLRVGAATNALKIALHYIKNA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=347, Percent_Identity=27.0893371757925, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=27.0422535211268, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38047; Mature: 38047

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYNVAIVGASGAVGQELIKGLENSSFPIKKFVPLASARSAGKKIKAFHKDYEILETMH
CCEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
EVFEKERIDIAFFSAGGSVSEEFATSAAKTALVIDNTSFFRLNKKVPLVVPEINAKEIFN
HHHHHCCCEEEEEECCCCCHHHHHHHHHCEEEEEECCCEEEECCCCCEEECCCCHHHHHC
APLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIEGLKNELKTALE
CCCEEEECCCCCEEEHHHHCCCHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CLEKDPAIDLNQVLQAGVFPYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPI
HHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCC
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASNT
CCHHEEEHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
DSAFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTYNVAIVGASGAVGQELIKGLENSSFPIKKFVPLASARSAGKKIKAFHKDYEILETMH
CCEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
EVFEKERIDIAFFSAGGSVSEEFATSAAKTALVIDNTSFFRLNKKVPLVVPEINAKEIFN
HHHHHCCCEEEEEECCCCCHHHHHHHHHCEEEEEECCCEEEECCCCCEEECCCCHHHHHC
APLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIEGLKNELKTALE
CCCEEEECCCCCEEEHHHHCCCHHEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
CLEKDPAIDLNQVLQAGVFPYPIAFNAIAHIDTFKENGYTKEELKMVHETHKIMGVDFPI
HHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCC
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVVVCDDPSHNLYPTPLKASNT
CCHHEEEHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCC
DSAFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
CHHHHHHHHHHHHHHHHHCCEEEHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]