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The map label for this gene is alr [H]

Identifier: 188527764

GI number: 188527764

Start: 983017

End: 984150

Strand: Reverse

Name: alr [H]

Synonym: HPSH_04955

Alternate gene names: 188527764

Gene position: 984150-983017 (Counterclockwise)

Preceding gene: 188527765

Following gene: 188527763

Centisome position: 61.18

GC content: 40.3

Gene sequence:

>1134_bases
ATGTTAAAAAGGGCGAGTTTTGTAGAAGTGAATACCGCTTCTTTAAGGCATAATTTTAGCGCAGTCAAAAGCATTGTCCC
TAAAGACGCCCACATCATGGCGGTTGTCAAGGCGAACGCTTATGGGGTGGGAGCCATAAAAGCGAGCGAAATTTTCTTAC
AAGAAGGGGCACATTATTTAGGGGTAGCGACCTTAGATGAAGCTTTAGAGTTGCACTCTCATTTTTCTAAAACCCCCATT
TTGATTTTAGGCTATAGCCCTAATTCTAACGCTTCCATGCTGATTGATAACGATTTGAGCGCTATGATTTTTAGCCTTGA
ACAAGCGGAAGTTTTTTCTCAAACGGCTTTAAAATCTCAAAAACGCTTAAAAGTGCATCTCAAAATTGATACCGGCATGC
ACCGCTTGGGTTTAGAGCCTAATTTTAAAAGCATAGAAATCATTAAAAAAATCCGCGCTTTAAAAGGCTTGGAAGTGGAA
GGGATATTCACGCATTTAAGCAACGCTGATGCTAAGATTAAAACCCATGCTAAAAACCAAATGAAAGCCTTTAACGCTTT
TTTAGAGCAGCTTTCAAATCAAAAAATAGAGTTTCAATACCGCCATGCTTACAATTCCGCCGGTATCCTTTCTTTGTGTA
ACGGGAATGAAAATCGCTTCTTAAACCTCTATCGCCCAGGGATCATGCTCTATGGTTTTTACCCTTCTAATGGAATGAAA
GAAACATGCCCAACCATTTTAAAAAATGTTATCAGTTTAAAAGCTCAAATCGTTCAAATCAGAAGCGTTAAAAAAGGCGA
ATTTATTGGCTATGGCGAGCATTTTTACACGAATGAAGAAACTTTAGTGGGTGTTTTAGCTCTAGGGTATGCAGACGGGT
TAATGCGCGCTTTAGGCAATCGCATTCAAGTAGCGATCAATAACCAATTAGCCCCCCTTATTGGCAAGGTGTGCATGGAT
CAATGCTTTGTTAAGCTCAATAATATTCAAGCCAAAGAGGGCGATGAGGTCATCTTGTTTGGGGATAAAAGCGCTAAGGC
TAACGATGCAAGCGAAATCGCTGCGCTTTTAAACACCATTCCTTATGAAACCATCAGCACCCTATCCAAACGCTTGGAGC
GCGTCTATATTTAA

Upstream 100 bases:

>100_bases
TATGGCTATCCCTAATTTGATTGCGTTGATTTTGTTGCATAAGGTAGTTTCTTCGGAAACTCGTTGGTATTTTAGCAAGC
ATTCTAACAAGTAAGACGGC

Downstream 100 bases:

>100_bases
AATCAAACCATGCAAAATTTTTATTTTGCGCTAGAATGCGCGAAAAACAAAATAGGATTGATTAAAAAATGAAAAAAGTT
TTATTTCTCTTTTTACTGGT

Product: alanine racemase, biosynthetic (alr)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLKRASFVEVNTASLRHNFSAVKSIVPKDAHIMAVVKANAYGVGAIKASEIFLQEGAHYLGVATLDEALELHSHFSKTPI
LILGYSPNSNASMLIDNDLSAMIFSLEQAEVFSQTALKSQKRLKVHLKIDTGMHRLGLEPNFKSIEIIKKIRALKGLEVE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLSNQKIEFQYRHAYNSAGILSLCNGNENRFLNLYRPGIMLYGFYPSNGMK
ETCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIAALLNTIPYETISTLSKRLERVYI

Sequences:

>Translated_377_residues
MLKRASFVEVNTASLRHNFSAVKSIVPKDAHIMAVVKANAYGVGAIKASEIFLQEGAHYLGVATLDEALELHSHFSKTPI
LILGYSPNSNASMLIDNDLSAMIFSLEQAEVFSQTALKSQKRLKVHLKIDTGMHRLGLEPNFKSIEIIKKIRALKGLEVE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLSNQKIEFQYRHAYNSAGILSLCNGNENRFLNLYRPGIMLYGFYPSNGMK
ETCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIAALLNTIPYETISTLSKRLERVYI
>Mature_377_residues
MLKRASFVEVNTASLRHNFSAVKSIVPKDAHIMAVVKANAYGVGAIKASEIFLQEGAHYLGVATLDEALELHSHFSKTPI
LILGYSPNSNASMLIDNDLSAMIFSLEQAEVFSQTALKSQKRLKVHLKIDTGMHRLGLEPNFKSIEIIKKIRALKGLEVE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLSNQKIEFQYRHAYNSAGILSLCNGNENRFLNLYRPGIMLYGFYPSNGMK
ETCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNNIQAKEGDEVILFGDKSAKANDASEIAALLNTIPYETISTLSKRLERVYI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=385, Percent_Identity=30.6493506493506, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787439, Length=384, Percent_Identity=28.3854166666667, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41813; Mature: 41813

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRASFVEVNTASLRHNFSAVKSIVPKDAHIMAVVKANAYGVGAIKASEIFLQEGAHYL
CCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEECEEHHHHHHHHCCCCEE
GVATLDEALELHSHFSKTPILILGYSPNSNASMLIDNDLSAMIFSLEQAEVFSQTALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHLKIDTGMHRLGLEPNFKSIEIIKKIRALKGLEVEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLSNQKIEFQYRHAYNSAGILSLCNGNENRFLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCH
ETCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNNIQAKEGDEVILFGDKSAKANDASEIAALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHC
PYETISTLSKRLERVYI
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKRASFVEVNTASLRHNFSAVKSIVPKDAHIMAVVKANAYGVGAIKASEIFLQEGAHYL
CCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEECEEHHHHHHHHCCCCEE
GVATLDEALELHSHFSKTPILILGYSPNSNASMLIDNDLSAMIFSLEQAEVFSQTALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHLKIDTGMHRLGLEPNFKSIEIIKKIRALKGLEVEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLSNQKIEFQYRHAYNSAGILSLCNGNENRFLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCH
ETCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNNIQAKEGDEVILFGDKSAKANDASEIAALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHC
PYETISTLSKRLERVYI
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA