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The map label for this gene is hypD2 [H]

Identifier: 188527724

GI number: 188527724

Start: 932848

End: 933960

Strand: Reverse

Name: hypD2 [H]

Synonym: HPSH_04735

Alternate gene names: 188527724

Gene position: 933960-932848 (Counterclockwise)

Preceding gene: 188527725

Following gene: 188527722

Centisome position: 58.06

GC content: 44.03

Gene sequence:

>1113_bases
ATGAGCGTTAACCATCTTATCGCCCCTTTTAGAGACAAGCAAACCATTTTAGCGCTCTCTAATGAAATCAAAAAACTCGC
TTTTAAACTTGAAAAAAAATTAGTCATCATGGAAGTGTGCGGAGGGCATACGCATTCTATCATGAAATACGGGCTTTTGG
ATTTGATGCCTAATTATTTAGAGTTCGTGCATGGGCCAGGGTGTCCGGTATGCGTGATGCCAAGAGCGCGCCTTGATGAA
GCTTATGAACTCGCCACAATCAAAGACAGCATCATCTTAAGTTTAGGGGATATGATGAAAGTCCCAGGGAGCTATGGGAG
TTTGATACAAGCCAGAGAAAAGGGGCTAGATGCGCGTTTTTTGTATTCGCCCATGCAAGCTTTAGAAATCGCTAAAGAAA
ACCCGCATAAAAAAGTCATTTATATTGCGATCGGTTTTGAAACCACAACGCCCATGAGCGCTAGCGTTTTATGGAACGCC
AAAAAAGAAAAAATCCACAACCTTTTTTTCCACATCAACCACGTTTTAGTGCCTCCTAGCGTGAGCGCGATTTTAAAAGA
TCCAGCATGCCAGATCAACGCCCTTTTAGCCCCTAGCCATGTGAGCGTGATAAGCGGCGCTCAAATCTATGCTCCATTAA
TTGATCGCTTCAAGCTCCCTATTGTGGTGAGCGGTTTTGAGCCGGTGGATATATTAGAAAGCGTGCTGATACTCATCAAA
CAAGCCTTAAAAAAAGAAGCCAAGCTAGAAATCCAGTATAAAAGAGCGGTTAGCTATGAGGGGAATGTGAAAGCGCAAGA
GTTAGTCCATGCATGCATGGAAGTTAGGGAAAATTTTGAATGGAGAGGTTTGGGGAATATCAAACATTCCGCTCTAAAAC
TCAAAGAAACCTTCGCTTCTTATGACGCTGAAAAAGTCTTTCAAGAATATTTAAGCCACAAAACCTCTAAAGAAAACAAG
GCATGCAAGTGCGGGGAGATTTTAAAAGGCATCGCCAAGCCCCTAGACTGCCCGCTATTTGCCAAAACTTGCACCCCACA
AAACCCGATCGGCAGTTGCATGGTCAGCTCTGAGGGAGCGTGCGCGGCGTATTATCGTTACAAGCGCGTTTGA

Upstream 100 bases:

>100_bases
TAAGATGGATGAAAAAGAAGCCCTAGAATCCATTGCACTTTATCAAGAAATGATCGCCAAAATGAACGAAACGCATGAAT
AATAAAACGCATGAGCAATA

Downstream 100 bases:

>100_bases
GCTTTAGAAATTGCTTTTTAGTGAAATCGCTCAAACCCTCGCAATGGACATTCACGCTTTTAGGGGGGTTTTCTTTTTTT
GCAACCGGTTTTTCATAAGC

Product: hydrogenase expression/formation protein (hypD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSVNHLIAPFRDKQTILALSNEIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNYLEFVHGPGCPVCVMPRARLDE
AYELATIKDSIILSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMSASVLWNA
KKEKIHNLFFHINHVLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLIDRFKLPIVVSGFEPVDILESVLILIK
QALKKEAKLEIQYKRAVSYEGNVKAQELVHACMEVRENFEWRGLGNIKHSALKLKETFASYDAEKVFQEYLSHKTSKENK
ACKCGEILKGIAKPLDCPLFAKTCTPQNPIGSCMVSSEGACAAYYRYKRV

Sequences:

>Translated_370_residues
MSVNHLIAPFRDKQTILALSNEIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNYLEFVHGPGCPVCVMPRARLDE
AYELATIKDSIILSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMSASVLWNA
KKEKIHNLFFHINHVLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLIDRFKLPIVVSGFEPVDILESVLILIK
QALKKEAKLEIQYKRAVSYEGNVKAQELVHACMEVRENFEWRGLGNIKHSALKLKETFASYDAEKVFQEYLSHKTSKENK
ACKCGEILKGIAKPLDCPLFAKTCTPQNPIGSCMVSSEGACAAYYRYKRV
>Mature_369_residues
SVNHLIAPFRDKQTILALSNEIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNYLEFVHGPGCPVCVMPRARLDEA
YELATIKDSIILSLGDMMKVPGSYGSLIQAREKGLDARFLYSPMQALEIAKENPHKKVIYIAIGFETTTPMSASVLWNAK
KEKIHNLFFHINHVLVPPSVSAILKDPACQINALLAPSHVSVISGAQIYAPLIDRFKLPIVVSGFEPVDILESVLILIKQ
ALKKEAKLEIQYKRAVSYEGNVKAQELVHACMEVRENFEWRGLGNIKHSALKLKETFASYDAEKVFQEYLSHKTSKENKA
CKCGEILKGIAKPLDCPLFAKTCTPQNPIGSCMVSSEGACAAYYRYKRV

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=367, Percent_Identity=43.3242506811989, Blast_Score=342, Evalue=3e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41265; Mature: 41134

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNHLIAPFRDKQTILALSNEIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH
EFVHGPGCPVCVMPRARLDEAYELATIKDSIILSLGDMMKVPGSYGSLIQAREKGLDARF
HHHCCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
LYSPMQALEIAKENPHKKVIYIAIGFETTTPMSASVLWNAKKEKIHNLFFHINHVLVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHEECCHHHHHHHHHHHHCEEECCCC
VSAILKDPACQINALLAPSHVSVISGAQIYAPLIDRFKLPIVVSGFEPVDILESVLILIK
HHHHHCCCCHHEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
QALKKEAKLEIQYKRAVSYEGNVKAQELVHACMEVRENFEWRGLGNIKHSALKLKETFAS
HHHHHHHHEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
YDAEKVFQEYLSHKTSKENKACKCGEILKGIAKPLDCPLFAKTCTPQNPIGSCMVSSEGA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECCCCC
CAAYYRYKRV
EEEHHHHHCC
>Mature Secondary Structure 
SVNHLIAPFRDKQTILALSNEIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNYL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHH
EFVHGPGCPVCVMPRARLDEAYELATIKDSIILSLGDMMKVPGSYGSLIQAREKGLDARF
HHHCCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
LYSPMQALEIAKENPHKKVIYIAIGFETTTPMSASVLWNAKKEKIHNLFFHINHVLVPPS
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHEECCHHHHHHHHHHHHCEEECCCC
VSAILKDPACQINALLAPSHVSVISGAQIYAPLIDRFKLPIVVSGFEPVDILESVLILIK
HHHHHCCCCHHEEEEECCCHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
QALKKEAKLEIQYKRAVSYEGNVKAQELVHACMEVRENFEWRGLGNIKHSALKLKETFAS
HHHHHHHHEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
YDAEKVFQEYLSHKTSKENKACKCGEILKGIAKPLDCPLFAKTCTPQNPIGSCMVSSEGA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECCCCC
CAAYYRYKRV
EEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]