BacMap

Definition	Helicobacter pylori Shi470, complete genome.
Accession	NC_010698
Length	1,608,548

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The map label for this gene is vdlC [H]

Identifier: 188527717

GI number: 188527717

Start: 927237

End: 928079

Strand: Reverse

Name: vdlC [H]

Synonym: HPSH_04695

Alternate gene names: 188527717

Gene position: 928079-927237 (Counterclockwise)

Preceding gene: 188527719

Following gene: 188527716

Centisome position: 57.7

GC content: 42.7

Gene sequence:

>843_bases
ATGGGCGAGAAAAAAGAAAGCCAAAAGGTGGCGGTTATCACCGGAGCGAGTTCTGGGATTGGGTTAGAGTGCGCGTTAAT
GCTGTTAGATCAAGGGTATAAAGTCTATGCGCTCTCTAGGCATGCGACTTTGTGCGTAGCGTTAAACCATGCGTTATGCG
AGAGTATTGATATTGATGTGAGCGATTCTAGCGCTTTAAAAGAAGCGTTTTTAAACATCAGCGCTAAAGAAGATCATTGC
GATGTTTTGATCAATTCCGCCGGTTATGGGGTGTTTGGGAGCGTAGAAGACACGCCTATTGACGAGGTTAAAAAACAATT
TGGCGTGAATTTTTTCGCCCTTTGTGAAGTGGTGCAGTTTTGTTTGCCCTTATTAAAAAACAAGCCCCACTCTAAAATTT
TTAATCTTTCTTCCATAGCGGGGCGTGTGAGCATGCTCTTTTTAGGCCATTACAGCGCAAGTAAGCATGCATTAGAGGCT
TATAGCGATGCCTTGCGTTTAGAGCTTAAACCCTTTAACGTTCAAGTGTGTTTGATTGAGCCAGGCCCGGTGAAAAGCAA
TTGGGAAAAAACCGCTTTTGAAAATGATGAGCGAAAAGATAGCCTTTATGCCTTAGAGGTGGATGCGGCCAAAAGCTTTT
ATTCTGGCGTGTATCAAAAAGCCCTAAGCCCTAAAGCCGTGGCGCAAAAAATCGTTTTTCTTGCCATGAGTCAAAAAATC
AAGGCCCGCTATTTGATCGGCTTAAAAACCCAATTATTGTTAGCGTTGTATAGAATCCTCCCTAACAGTTGGTATGATTC
TTTGTTCAGATTAATCGTTCTTAAAAGGAGGCGTGATGCTTAA

Upstream 100 bases:

>100_bases
TGTAAAAAACATTCCAAGAACTATATATTAGTAAAAATTAAGTAATATTAGGTGAATATTAGAGGAATTACAAAAATAAT
AAGAGAGTTGGCGTTAGATA

Downstream 100 bases:

>100_bases
AACCTATCATATTGCATTAGCTTGCGTGATTTTAGCGGTGGTGGTGCTTTTGTTTGGAGGGGAGTCCTTGAGCTTTGAAG
AATGGCAAGAAGTGTGCCTT

Product: short-chain oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MGEKKESQKVAVITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESIDIDVSDSSALKEAFLNISAKEDHC
DVLINSAGYGVFGSVEDTPIDEVKKQFGVNFFALCEVVQFCLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEA
YSDALRLELKPFNVQVCLIEPGPVKSNWEKTAFENDERKDSLYALEVDAAKSFYSGVYQKALSPKAVAQKIVFLAMSQKI
KARYLIGLKTQLLLALYRILPNSWYDSLFRLIVLKRRRDA

Sequences:

>Translated_280_residues
MGEKKESQKVAVITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESIDIDVSDSSALKEAFLNISAKEDHC
DVLINSAGYGVFGSVEDTPIDEVKKQFGVNFFALCEVVQFCLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEA
YSDALRLELKPFNVQVCLIEPGPVKSNWEKTAFENDERKDSLYALEVDAAKSFYSGVYQKALSPKAVAQKIVFLAMSQKI
KARYLIGLKTQLLLALYRILPNSWYDSLFRLIVLKRRRDA
>Mature_279_residues
GEKKESQKVAVITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESIDIDVSDSSALKEAFLNISAKEDHCD
VLINSAGYGVFGSVEDTPIDEVKKQFGVNFFALCEVVQFCLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAY
SDALRLELKPFNVQVCLIEPGPVKSNWEKTAFENDERKDSLYALEVDAAKSFYSGVYQKALSPKAVAQKIVFLAMSQKIK
ARYLIGLKTQLLLALYRILPNSWYDSLFRLIVLKRRRDA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=268, Percent_Identity=29.8507462686567, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7657478, Length=265, Percent_Identity=28.3018867924528, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI223718074, Length=272, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI22507405, Length=281, Percent_Identity=28.1138790035587, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=32.0855614973262, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7706318, Length=276, Percent_Identity=25.7246376811594, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI150247226, Length=200, Percent_Identity=32, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI44680136, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI44680133, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI17738292, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4504503, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4503817, Length=302, Percent_Identity=22.5165562913907, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=232, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI119392083, Length=206, Percent_Identity=27.6699029126214, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI50726952, Length=290, Percent_Identity=25.1724137931034, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=267, Percent_Identity=32.9588014981273, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=230, Percent_Identity=23.4782608695652, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367365, Length=204, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=23.2323232323232, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=269, Percent_Identity=30.1115241635688, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=197, Percent_Identity=31.9796954314721, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17557780, Length=196, Percent_Identity=30.1020408163265, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.3893129770992, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.1368821292776, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=290, Percent_Identity=27.2413793103448, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=290, Percent_Identity=27.2413793103448, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193210355, Length=293, Percent_Identity=28.6689419795222, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=237, Percent_Identity=27.8481012658228, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=286, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=28.6852589641434, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=282, Percent_Identity=25.177304964539, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=249, Percent_Identity=27.3092369477912, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=27.1653543307087, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=28.6821705426357, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=253, Percent_Identity=26.8774703557312, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=183, Percent_Identity=33.879781420765, Blast_Score=83, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21358495, Length=234, Percent_Identity=27.3504273504274, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=194, Percent_Identity=32.9896907216495, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=238, Percent_Identity=28.1512605042017, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=29.6875, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=30.1020408163265, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356301, Length=280, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651139, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45554248, Length=272, Percent_Identity=27.5735294117647, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24640117, Length=272, Percent_Identity=27.5735294117647, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355631, Length=280, Percent_Identity=24.6428571428571, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31079; Mature: 30948

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEKKESQKVAVITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESIDIDV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHCCCCC
SDSSALKEAFLNISAKEDHCDVLINSAGYGVFGSVEDTPIDEVKKQFGVNFFALCEVVQF
CCHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHH
CLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIE
HHHHHCCCCCHHHCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHEEEEECCEEEEEEEC
PGPVKSNWEKTAFENDERKDSLYALEVDAAKSFYSGVYQKALSPKAVAQKIVFLAMSQKI
CCCCCCCCCHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KARYLIGLKTQLLLALYRILPNSWYDSLFRLIVLKRRRDA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEKKESQKVAVITGASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALCESIDIDV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHCCCCC
SDSSALKEAFLNISAKEDHCDVLINSAGYGVFGSVEDTPIDEVKKQFGVNFFALCEVVQF
CCHHHHHHHHHCCCCCCCCCEEEECCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHH
CLPLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIE
HHHHHCCCCCHHHCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHEEEEECCEEEEEEEC
PGPVKSNWEKTAFENDERKDSLYALEVDAAKSFYSGVYQKALSPKAVAQKIVFLAMSQKI
CCCCCCCCCHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KARYLIGLKTQLLLALYRILPNSWYDSLFRLIVLKRRRDA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9139899; 9252185 [H]