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The map label for this gene is vacA [H]

Identifier: 188527713

GI number: 188527713

Start: 921330

End: 925193

Strand: Direct

Name: vacA [H]

Synonym: HPSH_04675

Alternate gene names: 188527713

Gene position: 921330-925193 (Clockwise)

Preceding gene: 188527712

Following gene: 188527718

Centisome position: 57.28

GC content: 41.95

Gene sequence:

>3864_bases
ATGGAAATACAACAAACACACCGCAAAATCAACCGCCCTTTGGTTTCTCTTGTTTTAGCAGGAGCGTTAATTAGTGCCAT
ACCGCAAGAAAGTCATGCCGCCTTTTTCACAACCGTGATCATTCCAGCCATTGTTGGGGGTATCGCTACAGGCACCGCTG
TAGGAACGGTCTCAGGGCTTCTTAGCTGGGGGCTCAAACAAGCCGAAGAAGCCAATAAAACCCCGGATAAACCCGATAAA
GTTTGGCGCATTCAAGCAGGAAGAGGCTTTAATGAATTCCCTAACAAGGAATACGACTTATACAAATCCCTTTTATCCAG
TAAGATTGATGGAGGTTGGGATTGGGGGAATGCTGCTAGACATTATTGGGTCAAAGGCGGGCAATGGAACAAGCTTGAAG
TGGATATGAAAGATGCTGTAGGGACTTATAAGCTTTCGGGCTTAAGAAACTACACTGGTGGGGATTTAGATGTCAATATG
CAAAAAGCCACTTTGCGCTTAGGCCAATTCAATGGCAATTCTTTCACAAGCTTTAAGGATGGTGCTGATCGCACCACGAG
AGTGGATTTCAACGCTAAAAATATCTCAATTGATAATTTTTTAGAAATCAATAACCGCGTGGGTTCTGGAGCCGGGAGGA
AAGCCAGCTCTACGGTTTTGACTTTGCAAGCTTCAGAAGGGATCACTAGCAGTAAAAACGCTGAAATTTCACTTTATGAT
GGTGCCACGCTTAATTTGGCTTCAAACAGCGTTAAATTAATGGGCAATGTGTGGATGGGCCGTTTGCAATATGTGGGAGC
GTATTTAGCCCCTTCATACAGCACGATAAACACTTCAAAAGTGACAGGGGAAGTGAATTTTAACCATCTCACTGTGGGCG
ATAGAAACGCCGCTCAAGCAGGGATTATCGCCAGTAAAAAGACTTATATTGGCACACTGGATTTGTGGCAAAGCGCGGGG
TTAAATATCATTGCCCCTCCAGAAGGCGGCTATAAGGATAAACCTGATAACACCACTCAAAACAGCGCTAAAAACGACAA
ACAAAAGAGCAGTCAAGATAATAGTAACACTCAGGTCATTAACCCACCCGATAGCGGGCAAAAAACAGAAATTCAACCCA
CGCAAGTCATTGATGGGCCTTTTGCTGGTGCCAAAGACACGGCTGTCACTATTGATAGCTTGAACACCAAATCTGATGGC
ACGATTAAAGTGGGAGGGTATAAAGCTTCTCTTACCACCAATGCAGCTAATTTGAATATCGGCAAAGGCGGTGTCAATCT
GTCCAATCAAGCGAGCGGGCGCTCTCTTTTAGTGGAAAATCTCACCGGCAATATCACCGTTAATGGGGCTTTAAAAGTGA
ATGGCCAAGCGGGTGGTTATGCCCTTTCAGGTTCGAGCGCGAATTTTGAATTTAAGGCTGGTGTGGATACCAAACAAGGC
ACAATCACTTTTAATAACAATATCAGTTTGGGAAGATTTGTGAATTTAAAAGCGAGCGCTCATACGGTCAATTTTAAAGA
TATTGATACTGGTAATGGTGGTTTCAACACCTTAGATTTTAGTGGTGTTACAAACAAGGTCAATATCAACAAGCTCATTA
CAGCTTCCACTAATGTGGCCATTAAAAACTTCAACATTAATGAATTGTTGGTTAAAACCAATGGGATAAGTGTGGGGGAA
TACACTCATTTTAGCGAAGATATAGGCAATCAATCGCGCATCAACACCGTGCGTTTAGAAACTGGCACTAGGTCAATCTA
TTCTGGGGGTGTTAAATTTAAAGGCGGTGAAAAACTGGTTATCAATGATTTTTACTACGCCCCTTGGAATTATTTTGACG
CTAGAAACATTAAAAATGTTGAAATCACCAATAAACTTGCTTTTGGGCCTCAAGGGAGTCCTTGGGGAACGGCAAAACTT
ATGTTTAATAATCTAACCCTAGGCCACAATGCAGTCATGGATTATAGTCAATTTTCAAATGTAACCATTCAAGGGGATTT
TGTCAATAATCAAGGCACTATCAATTATTTGGTTCGAGGCGGGAACATAGAAACCTTAAGCGTAGGCAATGCAGCTGCTA
TGATGTTTAATAATAGCGTGGATAGTGCGACTGGATTTTACAAACCGCTCATGAATATTAACAGTGCTCAAGATCTCATT
AAAAATAAAGAACATGTTTTATTGAAAGCGAAAATCATTGGTTATGACAATGTTTCTTTAGGCACTAACAGCATTAGTAA
TGTGAATCTAATAGAGCAGTTCAAAGAGCGCCTAGCCCTTTATAACAACAACAACCGCATGGATATTTGTGTGGTGCGCG
ATCTCAATGATGTTAAAGCATGCGGGACGGCTATCGGCAATACTGATATGGTGAATAACCCTAGCAATTATAAATACCTT
GTGGGTAAAGCATGGAGGAATATAGGGATTAGCAAAACAGCTAACGGCTCTAAAATTTCGGTGCGTTATTTAGGCAACTC
TACGCCTACTGAGAATAGTGGCAATACCACAAATTTACCCACAAACACCACTAAAAATGCGCGTTTCGCTAGCTACGCTC
TCATAAAGAACGCTCCTTTCGCTCAAGCTAGCGCCACTCCTAATTTAGTCGCTATCAATAAGCATGATTTTGGCACCATT
GAAAGCGTGTTTGAATTGGCTAACCGCTCTAAGGATATTGACACGCTTTATGCTAACTCAGGCGTGCAAGGCAGGGATCT
CTTACAAACCTTATTGATTGATAGCCATGATGCGGGTTATGCTAGAACCATGATTGATGCTACAAGCGCTAATGAAATCA
CCAAGCAATTGAATGAGGCCAATAGCGCTTTAAACAACATAGCCAGTTTGGATCATAAGACAAGCGGCTTGCAAACTTTG
AGCTTGAGCAATGCGATGATTTTAAATTCTCGTTTAGTCAATCTCTCCAGAAGGCACACCAACAATATCGACTCGTTCGC
CAAACGCTTGCAAGCTTTAGAAGGCCAAAGATTCGCTTCTTTAGAAAGCGCAGCAGAAGTGTTGTATCAATTTGCCCCTA
AATATGAAAAACCCACCAATGTTTGGGCTAACGCTATTGGGGGAGCGAGCTTGAATAATGGCGGTAACACTTCATTATAT
GGCACAAGCGCAGGCGTAGATGCTTACCTTAATGGGGAAGTAGAAGCCATTGTGGGCGGATTTGGAAGCTATGGTTATAG
CTCTTTTAATAATCAAGCGAACTCTCTTAACTCTGGGGCTAATAACGCTAATTTTGGCGTGTATAGCCGTATCTTTGCTA
ACCAGCATGAATTTGATTTTGAAGCTCAAGGGGCTGTAGGGAGTGATCAATCAAGCTTGAATTTCAAAAGCGCTTTATTG
CGAGATTTGAATCAAAGCTACAATTACTTAGCCTATAGCGCTGCAGCAAGAGCGAGCTATGGTTATGACTTCGCGTTTTT
TAGGAACGCTTTAGTGTTAAAACCAAGCGTGGGCGTGAGCTATAACCATTTAGGTTCAACCAACTTTGAAAGCAACAGCA
CCCATAAAGCGGCTTTAAAAAATGGCGCCAGCAGTCAGCATTTATTCAACGCTAGCGCTAATGTGGAAGCGCGTTATTAT
TATGGGGACACTTCATACTTCTATATGAATGCTGGAGTTTTACAAGAATTCGCTTCAGTTGGCTCTAAAACGGCTGCATC
TTTAAACACCTTTAAAGTGAATGTTGCTCGCAATCCTTTAAATACCCATGCTAGAGTGATGATGGGTGGGGAGTTGCAAT
TGGCTAAAGAAGTGTTTTTGAATTTGGGCTTTATTTATTTGCACAACTTGATTTCCAACGCAAGCCATTTCGCTTCCAAT
TTAGGAATGAGGTATAGTTTCTAA

Upstream 100 bases:

>100_bases
TTATAACCTTAATCGTAAATACAACAGAAATTTTCTAGTCTAAAGTCGCACCCTTTGTGCAAAAATCGTTTTACAAAAAG
AAAGGAAAGAAAGGAAGAAA

Downstream 100 bases:

>100_bases
GCTCTAAAACCCATGCTTTGGCATGGGTTTCTTAAGAAATAACATTTAAAACCACCCAAGCAGAAATCCCAAACATCTTT
AGTGTTTGGGATGAATGCCA

Product: vacuolating cytotoxin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1287; Mature: 1287

Protein sequence:

>1287_residues
MEIQQTHRKINRPLVSLVLAGALISAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGLLSWGLKQAEEANKTPDKPDK
VWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAARHYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNM
QKATLRLGQFNGNSFTSFKDGADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD
GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQAGIIASKKTYIGTLDLWQSAG
LNIIAPPEGGYKDKPDNTTQNSAKNDKQKSSQDNSNTQVINPPDSGQKTEIQPTQVIDGPFAGAKDTAVTIDSLNTKSDG
TIKVGGYKASLTTNAANLNIGKGGVNLSNQASGRSLLVENLTGNITVNGALKVNGQAGGYALSGSSANFEFKAGVDTKQG
TITFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINKLITASTNVAIKNFNINELLVKTNGISVGE
YTHFSEDIGNQSRINTVRLETGTRSIYSGGVKFKGGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKL
MFNNLTLGHNAVMDYSQFSNVTIQGDFVNNQGTINYLVRGGNIETLSVGNAAAMMFNNSVDSATGFYKPLMNINSAQDLI
KNKEHVLLKAKIIGYDNVSLGTNSISNVNLIEQFKERLALYNNNNRMDICVVRDLNDVKACGTAIGNTDMVNNPSNYKYL
VGKAWRNIGISKTANGSKISVRYLGNSTPTENSGNTTNLPTNTTKNARFASYALIKNAPFAQASATPNLVAINKHDFGTI
ESVFELANRSKDIDTLYANSGVQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNEANSALNNIASLDHKTSGLQTL
SLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALEGQRFASLESAAEVLYQFAPKYEKPTNVWANAIGGASLNNGGNTSLY
GTSAGVDAYLNGEVEAIVGGFGSYGYSSFNNQANSLNSGANNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKSALL
RDLNQSYNYLAYSAAARASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTHKAALKNGASSQHLFNASANVEARYY
YGDTSYFYMNAGVLQEFASVGSKTAASLNTFKVNVARNPLNTHARVMMGGELQLAKEVFLNLGFIYLHNLISNASHFASN
LGMRYSF

Sequences:

>Translated_1287_residues
MEIQQTHRKINRPLVSLVLAGALISAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGLLSWGLKQAEEANKTPDKPDK
VWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAARHYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNM
QKATLRLGQFNGNSFTSFKDGADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD
GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQAGIIASKKTYIGTLDLWQSAG
LNIIAPPEGGYKDKPDNTTQNSAKNDKQKSSQDNSNTQVINPPDSGQKTEIQPTQVIDGPFAGAKDTAVTIDSLNTKSDG
TIKVGGYKASLTTNAANLNIGKGGVNLSNQASGRSLLVENLTGNITVNGALKVNGQAGGYALSGSSANFEFKAGVDTKQG
TITFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINKLITASTNVAIKNFNINELLVKTNGISVGE
YTHFSEDIGNQSRINTVRLETGTRSIYSGGVKFKGGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKL
MFNNLTLGHNAVMDYSQFSNVTIQGDFVNNQGTINYLVRGGNIETLSVGNAAAMMFNNSVDSATGFYKPLMNINSAQDLI
KNKEHVLLKAKIIGYDNVSLGTNSISNVNLIEQFKERLALYNNNNRMDICVVRDLNDVKACGTAIGNTDMVNNPSNYKYL
VGKAWRNIGISKTANGSKISVRYLGNSTPTENSGNTTNLPTNTTKNARFASYALIKNAPFAQASATPNLVAINKHDFGTI
ESVFELANRSKDIDTLYANSGVQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNEANSALNNIASLDHKTSGLQTL
SLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALEGQRFASLESAAEVLYQFAPKYEKPTNVWANAIGGASLNNGGNTSLY
GTSAGVDAYLNGEVEAIVGGFGSYGYSSFNNQANSLNSGANNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKSALL
RDLNQSYNYLAYSAAARASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTHKAALKNGASSQHLFNASANVEARYY
YGDTSYFYMNAGVLQEFASVGSKTAASLNTFKVNVARNPLNTHARVMMGGELQLAKEVFLNLGFIYLHNLISNASHFASN
LGMRYSF
>Mature_1287_residues
MEIQQTHRKINRPLVSLVLAGALISAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGLLSWGLKQAEEANKTPDKPDK
VWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAARHYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNM
QKATLRLGQFNGNSFTSFKDGADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD
GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQAGIIASKKTYIGTLDLWQSAG
LNIIAPPEGGYKDKPDNTTQNSAKNDKQKSSQDNSNTQVINPPDSGQKTEIQPTQVIDGPFAGAKDTAVTIDSLNTKSDG
TIKVGGYKASLTTNAANLNIGKGGVNLSNQASGRSLLVENLTGNITVNGALKVNGQAGGYALSGSSANFEFKAGVDTKQG
TITFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINKLITASTNVAIKNFNINELLVKTNGISVGE
YTHFSEDIGNQSRINTVRLETGTRSIYSGGVKFKGGEKLVINDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKL
MFNNLTLGHNAVMDYSQFSNVTIQGDFVNNQGTINYLVRGGNIETLSVGNAAAMMFNNSVDSATGFYKPLMNINSAQDLI
KNKEHVLLKAKIIGYDNVSLGTNSISNVNLIEQFKERLALYNNNNRMDICVVRDLNDVKACGTAIGNTDMVNNPSNYKYL
VGKAWRNIGISKTANGSKISVRYLGNSTPTENSGNTTNLPTNTTKNARFASYALIKNAPFAQASATPNLVAINKHDFGTI
ESVFELANRSKDIDTLYANSGVQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNEANSALNNIASLDHKTSGLQTL
SLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALEGQRFASLESAAEVLYQFAPKYEKPTNVWANAIGGASLNNGGNTSLY
GTSAGVDAYLNGEVEAIVGGFGSYGYSSFNNQANSLNSGANNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKSALL
RDLNQSYNYLAYSAAARASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTHKAALKNGASSQHLFNASANVEARYY
YGDTSYFYMNAGVLQEFASVGSKTAASLNTFKVNVARNPLNTHARVMMGGELQLAKEVFLNLGFIYLHNLISNASHFASN
LGMRYSF

Specific function: Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Vacuolating cytotoxin translocator:Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR006315
- InterPro:   IPR003842 [H]

Pfam domain/function: PF02691 VacA [H]

EC number: NA

Molecular weight: Translated: 138854; Mature: 138854

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQQTHRKINRPLVSLVLAGALISAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LSWGLKQAEEANKTPDKPDKVWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR
HHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
HYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNMQKATLRLGQFNGNSFTSFKD
EEEEECCCCCEEEEEHHHCCCEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCC
GADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD
CCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEC
GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQA
CCEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEEEEECCCCCCCC
GIIASKKTYIGTLDLWQSAGLNIIAPPEGGYKDKPDNTTQNSAKNDKQKSSQDNSNTQVI
CEEECCCEEEEEHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEE
NPPDSGQKTEIQPTQVIDGPFAGAKDTAVTIDSLNTKSDGTIKVGGYKASLTTNAANLNI
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEEEE
GKGGVNLSNQASGRSLLVENLTGNITVNGALKVNGQAGGYALSGSSANFEFKAGVDTKQG
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCEEEEECCCCCCC
TITFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINKLITASTNVA
EEEECCCCCCCEEEEEEECEEEEEEEECCCCCCCCCEEECCCCCCEEECCEEEEECCCEE
IKNFNINELLVKTNGISVGEYTHFSEDIGNQSRINTVRLETGTRSIYSGGVKFKGGEKLV
EEECCCCEEEEEECCEECCCCCCCHHHCCCCCCEEEEEEECCCCHHHCCCEEECCCCEEE
INDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLGHNAVMDYSQFSN
EEEEEECCCCCCCCCCCCCEEEECEEEECCCCCCCCEEEEEEECEEECCHHHCCHHHHCC
VTIQGDFVNNQGTINYLVRGGNIETLSVGNAAAMMFNNSVDSATGFYKPLMNINSAQDLI
EEEEEEEECCCCEEEEEEECCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHH
KNKEHVLLKAKIIGYDNVSLGTNSISNVNLIEQFKERLALYNNNNRMDICVVRDLNDVKA
CCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEEEECCCHHHH
CGTAIGNTDMVNNPSNYKYLVGKAWRNIGISKTANGSKISVRYLGNSTPTENSGNTTNLP
HHHHCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
TNTTKNARFASYALIKNAPFAQASATPNLVAINKHDFGTIESVFELANRSKDIDTLYANS
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECC
GVQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNEANSALNNIASLDHKTSGLQTL
CCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALEGQRFASLESAAEVLYQFAPKYEKPTN
ECCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHH
VWANAIGGASLNNGGNTSLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFNNQANSLNSGA
HHHHCCCCCCCCCCCCCEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCC
NNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKSALLRDLNQSYNYLAYSAAARASY
CCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCC
GYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTHKAALKNGASSQHLFNASANVEARYY
CCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEE
YGDTSYFYMNAGVLQEFASVGSKTAASLNTFKVNVARNPLNTHARVMMGGELQLAKEVFL
ECCCEEEEECHHHHHHHHHCCCHHHCCEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHH
NLGFIYLHNLISNASHFASNLGMRYSF
HHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MEIQQTHRKINRPLVSLVLAGALISAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LSWGLKQAEEANKTPDKPDKVWRIQAGRGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR
HHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
HYWVKGGQWNKLEVDMKDAVGTYKLSGLRNYTGGDLDVNMQKATLRLGQFNGNSFTSFKD
EEEEECCCCCEEEEEHHHCCCEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCC
GADRTTRVDFNAKNISIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD
CCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEC
GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDRNAAQA
CCEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEEEEECCCCCCCC
GIIASKKTYIGTLDLWQSAGLNIIAPPEGGYKDKPDNTTQNSAKNDKQKSSQDNSNTQVI
CEEECCCEEEEEHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEE
NPPDSGQKTEIQPTQVIDGPFAGAKDTAVTIDSLNTKSDGTIKVGGYKASLTTNAANLNI
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEEEE
GKGGVNLSNQASGRSLLVENLTGNITVNGALKVNGQAGGYALSGSSANFEFKAGVDTKQG
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCEEEEECCCCCCC
TITFNNNISLGRFVNLKASAHTVNFKDIDTGNGGFNTLDFSGVTNKVNINKLITASTNVA
EEEECCCCCCCEEEEEEECEEEEEEEECCCCCCCCCEEECCCCCCEEECCEEEEECCCEE
IKNFNINELLVKTNGISVGEYTHFSEDIGNQSRINTVRLETGTRSIYSGGVKFKGGEKLV
EEECCCCEEEEEECCEECCCCCCCHHHCCCCCCEEEEEEECCCCHHHCCCEEECCCCEEE
INDFYYAPWNYFDARNIKNVEITNKLAFGPQGSPWGTAKLMFNNLTLGHNAVMDYSQFSN
EEEEEECCCCCCCCCCCCCEEEECEEEECCCCCCCCEEEEEEECEEECCHHHCCHHHHCC
VTIQGDFVNNQGTINYLVRGGNIETLSVGNAAAMMFNNSVDSATGFYKPLMNINSAQDLI
EEEEEEEECCCCEEEEEEECCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHH
KNKEHVLLKAKIIGYDNVSLGTNSISNVNLIEQFKERLALYNNNNRMDICVVRDLNDVKA
CCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCEEEEEEEECCCHHHH
CGTAIGNTDMVNNPSNYKYLVGKAWRNIGISKTANGSKISVRYLGNSTPTENSGNTTNLP
HHHHCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
TNTTKNARFASYALIKNAPFAQASATPNLVAINKHDFGTIESVFELANRSKDIDTLYANS
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECC
GVQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNEANSALNNIASLDHKTSGLQTL
CCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SLSNAMILNSRLVNLSRRHTNNIDSFAKRLQALEGQRFASLESAAEVLYQFAPKYEKPTN
ECCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHH
VWANAIGGASLNNGGNTSLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFNNQANSLNSGA
HHHHCCCCCCCCCCCCCEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCC
NNANFGVYSRIFANQHEFDFEAQGAVGSDQSSLNFKSALLRDLNQSYNYLAYSAAARASY
CCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCC
GYDFAFFRNALVLKPSVGVSYNHLGSTNFESNSTHKAALKNGASSQHLFNASANVEARYY
CCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEEEE
YGDTSYFYMNAGVLQEFASVGSKTAASLNTFKVNVARNPLNTHARVMMGGELQLAKEVFL
ECCCEEEEECHHHHHHHHHCCCHHHCCEEEEEEEEECCCCCCCEEEEECCCHHHHHHHHH
NLGFIYLHNLISNASHFASNLGMRYSF
HHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8168917; 8163943 [H]