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The map label for this gene is cysS

Identifier: 188527712

GI number: 188527712

Start: 919700

End: 921097

Strand: Direct

Name: cysS

Synonym: HPSH_04670

Alternate gene names: 188527712

Gene position: 919700-921097 (Clockwise)

Preceding gene: 188527711

Following gene: 188527713

Centisome position: 57.18

GC content: 38.7

Gene sequence:

>1398_bases
ATGTTTATTTATGATACCAAATTAAAACAAAAAGTCCCTTTTGAGCCTTTAGTTGAAAAAAAGGCGAATATTTATGTGTG
CGGGCCTACGGTGTATGATGACGCTCATTTAGGGCATGCTAGGAGTGCGATTGCTTTTGATTTGTTAAGGCGCACGCTTG
AATTGAGCGGCTATGAAGTGGTGCTAGTAAGGAATTTCACGGATATTGACGACAAAATCATCAACAAAGCCCTAAAAGAA
AACAAAAGCATTCAAGAATTAAGCAGCATTTATATTGAATCTTACACGAGGGATTTAAACGCTTTGAACGTGAAAAAACC
CAGCCTAGAGCCTAAAGCGAGCGAGTATTTAGACGCTATGGTGGGCATGATTGAAACGCTTTTAGAAAAAAATATCGCTT
ATCAGATCTCTAATGGGGATATTTATTTAGACACGAGCAAGGATAAAGATTACGGCTCTTTGAGCGTGCATAATAGCAGT
ATTGAATTTGGCCGTATTGGTTTGGTGCAAGAAAAACGGCTTGAGCAGGATTTTGTGTTATGGAAAAGCTATAAGGGGGA
TAATGATGTGGGCTTTGATAGCCCTTTAGGCAAAGGGCGCCCTGGCTGGCATATAGAATGCTCTAGCATGATCTTTAAAA
CTTTAGCGCTCACTGACACCCCTTATCAAATTGACATCCATGCAGGCGGAGCGGATTTGTTATTCCCCCACCATGAAAAT
GAAGCGTGCCAAACCCGTTGCGCCTTTGGCGTGGAGCTTGCTAAATACTGGATGCATAATGGCTTTGTGAATATCAATAA
CGAAAAAATGTCTAAAAGTTTAGGGAATAGCTTTTTTATTAAAGACGCCCTCAAAAACTATGATGGCGAAATTTTGCGCA
ATTACTTGCTAGGGGTGCATTATCGCTCTGTTTTGAATTTCAATGAAGAAGACTTACTGATGAGTAAAAAACGCTTGGAT
AAAATCTATCGTTTAAAACAGCGCGTTTTAGGGACTCTTGGAGGAATAAATCCAAACTTTAAAAAAGAAATTTTAGAATG
CATGCAAGACGATTTAAACATTTCTAAAGCGTTGAGCGTTTTAGAAAGCATGCTTTCTTCTACTAATGAAAAACTGGATC
AAAACCCCAAAAACAAGGCTTTGAAAGGCGAAATTTTAGCGAATTTAAAATTCATAGAAGAACTGCTTGGCATCGGGTTT
AAAGACCCTGTAGAATATTTCCAATTAGGCGTGAGTGGGAGCGAAAAACAAGAAATTGAAAACAAGATAGAAGAAAGGAA
ACGCGCCAAAGAGCAAAAAGATTTTTTAAAAGCCGATAACATCAGAGAAGAGCTTTTGAAACAAAAAATCGCTTTGATGG
ACACCCCACAAGGCACGATCTGGGAGAAGTTTTTTTAA

Upstream 100 bases:

>100_bases
TGTAATTCTTTTCCTCGCTTGCGTGGAAATCTTATTACTCTTAGCGTTCAAATCGTGGGTTACACATTTATATTTATTTT
ATTATTTTCAAGGTTTTTAA

Downstream 100 bases:

>100_bases
AACGCCTCCAATTTTACCTTTTTACACATTCTAGCCACAAATTTCAGCATTTTTGCTTTTTAATCTTATATGTTTTATAT
TTATTTACCTATTACTTGAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MFIYDTKLKQKVPFEPLVEKKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVVLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVGMIETLLEKNIAYQISNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMIFKTLALTDTPYQIDIHAGGADLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLMSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNISKALSVLESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGF
KDPVEYFQLGVSGSEKQEIENKIEERKRAKEQKDFLKADNIREELLKQKIALMDTPQGTIWEKFF

Sequences:

>Translated_465_residues
MFIYDTKLKQKVPFEPLVEKKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVVLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVGMIETLLEKNIAYQISNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMIFKTLALTDTPYQIDIHAGGADLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLMSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNISKALSVLESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGF
KDPVEYFQLGVSGSEKQEIENKIEERKRAKEQKDFLKADNIREELLKQKIALMDTPQGTIWEKFF
>Mature_465_residues
MFIYDTKLKQKVPFEPLVEKKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVVLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVGMIETLLEKNIAYQISNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMIFKTLALTDTPYQIDIHAGGADLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLMSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNISKALSVLESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGF
KDPVEYFQLGVSGSEKQEIENKIEERKRAKEQKDFLKADNIREELLKQKIALMDTPQGTIWEKFF

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=430, Percent_Identity=32.5581395348837, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI303304987, Length=390, Percent_Identity=29.2307692307692, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI62240992, Length=390, Percent_Identity=28.974358974359, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI21269877, Length=390, Percent_Identity=28.974358974359, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI10835051, Length=390, Percent_Identity=28.974358974359, Blast_Score=147, Evalue=3e-35,
Organism=Escherichia coli, GI1786737, Length=468, Percent_Identity=39.5299145299145, Blast_Score=332, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17509797, Length=258, Percent_Identity=31.0077519379845, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17509795, Length=258, Percent_Identity=31.0077519379845, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324082, Length=371, Percent_Identity=29.6495956873315, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI19922218, Length=505, Percent_Identity=29.5049504950495, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI19922364, Length=267, Percent_Identity=32.9588014981273, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53201; Mature: 53201

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIYDTKLKQKVPFEPLVEKKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEV
CEEECCCCCCCCCCCHHHHCCCCEEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
VLVRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAM
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
VGMIETLLEKNIAYQISNGDIYLDTSKDKDYGSLSVHNSSIEFGRIGLVQEKRLEQDFVL
HHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
WKSYKGDNDVGFDSPLGKGRPGWHIECSSMIFKTLALTDTPYQIDIHAGGADLLFPHHEN
HHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCCC
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVH
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
YRSVLNFNEEDLLMSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNISKALSV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
LESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGFKDPVEYFQLGVSGSEKQEIE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHH
NKIEERKRAKEQKDFLKADNIREELLKQKIALMDTPQGTIWEKFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MFIYDTKLKQKVPFEPLVEKKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEV
CEEECCCCCCCCCCCHHHHCCCCEEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
VLVRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAM
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
VGMIETLLEKNIAYQISNGDIYLDTSKDKDYGSLSVHNSSIEFGRIGLVQEKRLEQDFVL
HHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
WKSYKGDNDVGFDSPLGKGRPGWHIECSSMIFKTLALTDTPYQIDIHAGGADLLFPHHEN
HHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCCC
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVH
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
YRSVLNFNEEDLLMSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNISKALSV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
LESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGFKDPVEYFQLGVSGSEKQEIE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHH
NKIEERKRAKEQKDFLKADNIREELLKQKIALMDTPQGTIWEKFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA