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The map label for this gene is era

Identifier: 188527646

GI number: 188527646

Start: 846981

End: 847886

Strand: Reverse

Name: era

Synonym: HPSH_04340

Alternate gene names: 188527646

Gene position: 847886-846981 (Counterclockwise)

Preceding gene: 188527647

Following gene: 188527645

Centisome position: 52.71

GC content: 37.86

Gene sequence:

>906_bases
ATGAAAACTAAGGCGGGCTTTGTAGCTCTTATAGGCAAACCAAACGCTGGAAAAAGCACTCTTTTAAACACTTTATTAAA
CGCTCATTTAGCCCTCGTTTCGCATAAGGCTAATGCGACAAGAAAATTAATGAAATGCATCGTGCCTTTTAAAGATAAAG
AGGGGTATGAGAGCCAGATCATTTTTTTAGACACACCAGGGCTTCATCATCAAGAAAAATTACTCAACCAATGCATGCTC
TCACAGGCTTTAAAAGCGATGGGCGATGCTGAGTTGTGCGTTTTTTTAGCTTCTGTGCATGATGATTTAAAAGGCTATGA
AGAGTTTTTGAGTTTGTGCCAAAAACCCCATATCTTGGCTGTGAGTAAGATTGACACCGCCGTACATAAGCAGGTTTTGC
AAAAATTGCAAGAGTATCAACAATACGCTTCGCAATTTTTAGCTCTCGTGCCTTTGAGCGCGAAAAAATCTCAAAATTTA
AACGCGCTTTTAGAATGCATCAGTAAGCATTTAAGCCCTAGTGCATGGCTTTTTGAAAAGGATTTGATGAGCGATGAAAA
AATGTGCGATATTTATAAGGAAATCATTAGGGAGAGTTTGTTTGATTTTTTGAGCGATGAAATCCCTTATGAAAGCGATG
TGATGATTGATAAATTTATAGAAGAAGAACGCATAGATAAGGTGTATGCACATATTATCGTAGAAAAAGAAAGCCAAAAA
AAAATCGTGATAGGCAAAAACGGGGTGAATATCAAACGCATCGGGACTAACGCGCGATTGAAAATGCAAGAAGTGGGCGA
AAAAAAGGTTTTTTTAAACTTGCAAGTGATCGCTCAAAAATCATGGAGCAAGGAAGAAAAGAGCTTGCAAAAACTGGGTT
ATATCTATCAAAGGAATAGGGATTGA

Upstream 100 bases:

>100_bases
AGAATTATTCTGGGCAAAATGTTACTATCACTAAAGAGTTGGTCCAATCAAAGCTAGAGGATTTAGTGGCTGATGAAAAT
TTAGTGAAGTATATTTTATA

Downstream 100 bases:

>100_bases
AAAAAATATTACCGGCTCTGTTAATGGGGTTTGTAGGATTGAATGCTGATGAGCGTTTGTTAGAAATTATGCGCCTTTAT
CAAAAGCAAGGCTTGGAAGT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILAVSKIDTAVHKQVLQKLQEYQQYASQFLALVPLSAKKSQNL
NALLECISKHLSPSAWLFEKDLMSDEKMCDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQK
KIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNRD

Sequences:

>Translated_301_residues
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILAVSKIDTAVHKQVLQKLQEYQQYASQFLALVPLSAKKSQNL
NALLECISKHLSPSAWLFEKDLMSDEKMCDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQK
KIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNRD
>Mature_301_residues
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQIIFLDTPGLHHQEKLLNQCML
SQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILAVSKIDTAVHKQVLQKLQEYQQYASQFLALVPLSAKKSQNL
NALLECISKHLSPSAWLFEKDLMSDEKMCDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQK
KIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNRD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=39.202657807309, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34328; Mature: 34328

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IFLDTPGLHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VSKIDTAVHKQVLQKLQEYQQYASQFLALVPLSAKKSQNLNALLECISKHLSPSAWLFEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
DLMSDEKMCDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQK
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
KIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNR
EEEEECCCCEEEEECCCCEEEHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCC
D
C
>Mature Secondary Structure
MKTKAGFVALIGKPNAGKSTLLNTLLNAHLALVSHKANATRKLMKCIVPFKDKEGYESQI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IFLDTPGLHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILA
EEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VSKIDTAVHKQVLQKLQEYQQYASQFLALVPLSAKKSQNLNALLECISKHLSPSAWLFEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
DLMSDEKMCDIYKEIIRESLFDFLSDEIPYESDVMIDKFIEEERIDKVYAHIIVEKESQK
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
KIVIGKNGVNIKRIGTNARLKMQEVGEKKVFLNLQVIAQKSWSKEEKSLQKLGYIYQRNR
EEEEECCCCEEEEECCCCEEEHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA