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The map label for this gene is rho

Identifier: 188527605

GI number: 188527605

Start: 801553

End: 802869

Strand: Direct

Name: rho

Synonym: HPSH_04135

Alternate gene names: 188527605

Gene position: 801553-802869 (Clockwise)

Preceding gene: 188527599

Following gene: 188527606

Centisome position: 49.83

GC content: 42.75

Gene sequence:

>1317_bases
ATGAACGAAAACGCGCCTGCACACAAGAGTCCGCACAAAGTCAAAACACACACGCCAGTGAGCGGTTATCACATTGAAGA
TTTACGCACTTACCCTACTGAAAAGCTTTTAGAAATCGCTAACAAGCTCAAAGTGGAAAACCCCCAAGAATTCAAACGAC
AAGACTTGATGTTTGAAATTTTAAAAACCCAAGTTACGCAAGGCGGATACATTCTTTTTACCGGGATTTTAGAAATCATG
CCTGATGGCTATGGCTTTTTAAGAGGGTTTGATGGGAGTTTTTCAGACGGGCATAACGACACTTATGTCAGCCCTTCTCA
AATCAGGCGTTTTGCTTTAAGGAATGGCGATATTGTTACCGGTCAAGTGCGATCCCCCAAAGACCAGGAAAAATACTACG
CCCTTTTAAAAATAGAAGCCATCAATTATTTGCCTTCAGATGAGATTAAAAACCGCCCTTTGTTTGACAATCTAACCCCC
CTATTCCCGGATGAACCAATCAAATTAGAATACGAACCCACTAAAGTTACCGGCAGAATGCTAGATTTATTCAGCCCTGT
GGGGAAAGGTCAAAGGGCTTTGATCGTCGCGCCACCAAGAACCGGGAAAACGGAGCTCATGAAAGAACTCGCCCAAGGCA
TCACCTCTAACCACCCTGAAGTGGAACTGATTATCCTTTTAGTGGATGAGCGCCCTGAAGAAGTTACGGATATGCAACGA
AGCGTTAAAGGTCAAGTTTTTAGCTCCACTTTTGATTTGCCCGCAAACAACCACATAAGAATCGCTGAATTAGTCCTAGA
AAGGGCTAAAAGGCGAGTGGAAATGGGAAAAGATGTGGTGGTTTTATTGGATTCTATCACCCGTTTAGCCAGAGCGTATA
ACGCTGTAACGCCTTCAAGCGGTAAGGTTTTAAGTGGAGGCGTGGATGCGAACGCCTTGCACAGGCCCAAGCGCTTTTTT
GGAGCGGCAAGGAATATTGAAGAAGGCGGGAGCTTGACGATTATCGCTACTGCATTGATTGAAACGGGATCTAGAATGGA
TGAGGTGATTTTTGAAGAATTTAAAGGCACCGGGAATAGCGAAATCGTTTTAGCGAGGAATATTGCAGACAGGCGCATTT
ACCCGGCCTTTGATATTTTAAAATCCGGCACACGAAAAGATAATATCTTGCTTGGCAAAGACCGCTTGACTAAAGTGTGG
GTTTTAAGGAATGTGATGCAACAAATGGATGACATAGAAGCCTTAAGCTTTGTGTATTCTAAAATGCAACAAACTAAGGA
CAATGAAGAATTTTTAAATTTAATGAATGAAAAATAA

Upstream 100 bases:

>100_bases
AAATATCTTGTTGGTTACACCATTTTGCCTTATTTGCTTTTTGTATTTTTTATCTTAATTGCAACAAACTAGAAATCTCT
TTTTGTTAAAAGGAAATTTA

Downstream 100 bases:

>100_bases
AATCCCTAATTAATCCCATTAATTAAAAAAGTGTCATGAAAATAGGCGTTTTTGATAGCGGTGTGGGAGGTTTTAGCGTT
TTAAAAAGCCTTTTAAAAGC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNENAPAHKSPHKVKTHTPVSGYHIEDLRTYPTEKLLEIANKLKVENPQEFKRQDLMFEILKTQVTQGGYILFTGILEIM
PDGYGFLRGFDGSFSDGHNDTYVSPSQIRRFALRNGDIVTGQVRSPKDQEKYYALLKIEAINYLPSDEIKNRPLFDNLTP
LFPDEPIKLEYEPTKVTGRMLDLFSPVGKGQRALIVAPPRTGKTELMKELAQGITSNHPEVELIILLVDERPEEVTDMQR
SVKGQVFSSTFDLPANNHIRIAELVLERAKRRVEMGKDVVVLLDSITRLARAYNAVTPSSGKVLSGGVDANALHRPKRFF
GAARNIEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNSEIVLARNIADRRIYPAFDILKSGTRKDNILLGKDRLTKVW
VLRNVMQQMDDIEALSFVYSKMQQTKDNEEFLNLMNEK

Sequences:

>Translated_438_residues
MNENAPAHKSPHKVKTHTPVSGYHIEDLRTYPTEKLLEIANKLKVENPQEFKRQDLMFEILKTQVTQGGYILFTGILEIM
PDGYGFLRGFDGSFSDGHNDTYVSPSQIRRFALRNGDIVTGQVRSPKDQEKYYALLKIEAINYLPSDEIKNRPLFDNLTP
LFPDEPIKLEYEPTKVTGRMLDLFSPVGKGQRALIVAPPRTGKTELMKELAQGITSNHPEVELIILLVDERPEEVTDMQR
SVKGQVFSSTFDLPANNHIRIAELVLERAKRRVEMGKDVVVLLDSITRLARAYNAVTPSSGKVLSGGVDANALHRPKRFF
GAARNIEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNSEIVLARNIADRRIYPAFDILKSGTRKDNILLGKDRLTKVW
VLRNVMQQMDDIEALSFVYSKMQQTKDNEEFLNLMNEK
>Mature_438_residues
MNENAPAHKSPHKVKTHTPVSGYHIEDLRTYPTEKLLEIANKLKVENPQEFKRQDLMFEILKTQVTQGGYILFTGILEIM
PDGYGFLRGFDGSFSDGHNDTYVSPSQIRRFALRNGDIVTGQVRSPKDQEKYYALLKIEAINYLPSDEIKNRPLFDNLTP
LFPDEPIKLEYEPTKVTGRMLDLFSPVGKGQRALIVAPPRTGKTELMKELAQGITSNHPEVELIILLVDERPEEVTDMQR
SVKGQVFSSTFDLPANNHIRIAELVLERAKRRVEMGKDVVVLLDSITRLARAYNAVTPSSGKVLSGGVDANALHRPKRFF
GAARNIEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNSEIVLARNIADRRIYPAFDILKSGTRKDNILLGKDRLTKVW
VLRNVMQQMDDIEALSFVYSKMQQTKDNEEFLNLMNEK

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=415, Percent_Identity=54.2168674698795, Blast_Score=484, Evalue=1e-138,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 49494; Mature: 49494

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNENAPAHKSPHKVKTHTPVSGYHIEDLRTYPTEKLLEIANKLKVENPQEFKRQDLMFEI
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKTQVTQGGYILFTGILEIMPDGYGFLRGFDGSFSDGHNDTYVSPSQIRRFALRNGDIVT
HHHHHCCCCEEHEEHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEE
GQVRSPKDQEKYYALLKIEAINYLPSDEIKNRPLFDNLTPLFPDEPIKLEYEPTKVTGRM
CCCCCCCCHHHEEEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
LDLFSPVGKGQRALIVAPPRTGKTELMKELAQGITSNHPEVELIILLVDERPEEVTDMQR
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHH
SVKGQVFSSTFDLPANNHIRIAELVLERAKRRVEMGKDVVVLLDSITRLARAYNAVTPSS
HHCCHHHHCEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
GKVLSGGVDANALHRPKRFFGAARNIEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNS
CCEEECCCCCHHHHCCHHHHHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCC
EIVLARNIADRRIYPAFDILKSGTRKDNILLGKDRLTKVWVLRNVMQQMDDIEALSFVYS
EEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMQQTKDNEEFLNLMNEK
HHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MNENAPAHKSPHKVKTHTPVSGYHIEDLRTYPTEKLLEIANKLKVENPQEFKRQDLMFEI
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKTQVTQGGYILFTGILEIMPDGYGFLRGFDGSFSDGHNDTYVSPSQIRRFALRNGDIVT
HHHHHCCCCEEHEEHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEE
GQVRSPKDQEKYYALLKIEAINYLPSDEIKNRPLFDNLTPLFPDEPIKLEYEPTKVTGRM
CCCCCCCCHHHEEEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
LDLFSPVGKGQRALIVAPPRTGKTELMKELAQGITSNHPEVELIILLVDERPEEVTDMQR
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHH
SVKGQVFSSTFDLPANNHIRIAELVLERAKRRVEMGKDVVVLLDSITRLARAYNAVTPSS
HHCCHHHHCEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
GKVLSGGVDANALHRPKRFFGAARNIEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNS
CCEEECCCCCHHHHCCHHHHHHHCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCC
EIVLARNIADRRIYPAFDILKSGTRKDNILLGKDRLTKVWVLRNVMQQMDDIEALSFVYS
EEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMQQTKDNEEFLNLMNEK
HHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]