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The map label for this gene is queC [H]

Identifier: 188527512

GI number: 188527512

Start: 704130

End: 704810

Strand: Direct

Name: queC [H]

Synonym: HPSH_03670

Alternate gene names: 188527512

Gene position: 704130-704810 (Clockwise)

Preceding gene: 188527501

Following gene: 188527514

Centisome position: 43.77

GC content: 38.91

Gene sequence:

>681_bases
ATGGAACAAGAAATTTGCGCAATCAGTTTTAGCGGCGGGCAAGACAGCACCACTTTAGCCGTATGGGCGAAAAAGCGTTT
TAAAAAAGTTTATTTAGTGGGGTTTGATTACGCGCAAAAACACTCTGTGGAATTAGAATGCGCTCAAAAAATCGCTTCTC
TTTTACAACTCCCTTATGAAATCATCCCATTAGATTTTTTAGAGAATATCACCCACTCTGCGCTTTTTAAAAACTCTAAC
GATTTAATGGGGCATTCGCATGCGCAAAATAAAGATTTACCCAACTCTTTTGTGCCTAATCGTAACGCTATTTTTATCAC
CCTTTTGCATTCTTATGCGCAAAAAATAGGGGCTAGTAACATCGCTTTAGGGGTTTCGCAAGCGGATTTTAGCGGCTATC
CGGATTGTAAAGAAGATTTCATTAAAAGCATCGAGCATGCGCTCAATTTAGGATCAAACACGGCGATTAAAATCCTAACG
CCTTTAATGTTTTTGAATAAAGCGCAAGAATTTCAAATGGCTAAAGATTTAGGCGTCTTGGATTTAGTCATCAAAGAAAC
GCACACCTGCTATCAAGGAGAGCGAAAGATTTTGCATGCTTATGGTTATGGCTGCGGTGAATGCCCGGCATGCCAATTGA
GAAAAAAAGGCTATGAAGAGTTTGAATCTAATAAAAAATAA

Upstream 100 bases:

>100_bases
GTCAAACAATTCTTGTAATTCTTTGTCTAACTCAAACACGCTTTTTACTCTTAAAATTTCTTTGTGTTATTATATCTTTT
TAGAATTTTAAGGAATTTTG

Downstream 100 bases:

>100_bases
GGCTTTGTTTTAAAAAACCAACTAAAGAGCATTAAAAGGCATGTTTTAATGTTTGTTTTTAAAGTTAGTTTTAAAGTTAT
ATGTATAGTTAAGATAAACG

Product: ExsB trans-regulatory protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEQEICAISFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITHSALFKNSN
DLMGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCGECPACQLRKKGYEEFESNKK

Sequences:

>Translated_226_residues
MEQEICAISFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITHSALFKNSN
DLMGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCGECPACQLRKKGYEEFESNKK
>Mature_226_residues
MEQEICAISFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITHSALFKNSN
DLMGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCGECPACQLRKKGYEEFESNKK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=219, Percent_Identity=38.8127853881278, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25316; Mature: 25316

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQEICAISFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQLPYE
CCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCHH
IIPLDFLENITHSALFKNSNDLMGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASN
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCH
IALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVL
HEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
DLVIKETHTCYQGERKILHAYGYGCGECPACQLRKKGYEEFESNKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MEQEICAISFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQLPYE
CCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCHH
IIPLDFLENITHSALFKNSNDLMGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKIGASN
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCH
IALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVL
HEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
DLVIKETHTCYQGERKILHAYGYGCGECPACQLRKKGYEEFESNKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA