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The map label for this gene is 188527396

Identifier: 188527396

GI number: 188527396

Start: 579251

End: 580762

Strand: Direct

Name: 188527396

Synonym: HPSH_03025

Alternate gene names: NA

Gene position: 579251-580762 (Clockwise)

Preceding gene: 188527395

Following gene: 188527413

Centisome position: 36.01

GC content: 42.06

Gene sequence:

>1512_bases
ATGAAAAAGATCTATTATGCTAGAGGGCAAACCATTTTAAAAGGCGCTTCAGCTAAAGCCAAATTAATGGAGTTTCAAGC
GAAATCTTTTGTGGAAGCTGAAGAGATGCGCATGAAAAGCCAAGAATGCAAATTGCAACAGCAATACGAAAATAAAAATT
TGCAACTCCAAACCCATTTTGAAAAAAAAGAAGTGCATTTGAAGCATTTAGAAGCGCAACACAAAGAATTTGTAAGAGAT
GAAAAACGCTATTTGGAAAAGGAAAAACAAGAGCTTGAAAAAGAACGCCAAATTTTAGAGCAAGAAAAAGAAAATTTTAA
AAAACAGTGCGCTGTTTGCAAAGAAGCTCAAGCCAAAGCGCTAGATGCGATGCTTAATTACATGGCTTATACCAAAGATG
AAATTAAAAACATGGTTTTAGAGCAATTAGAAGAAGAATTAGAAGTGCAAAAAAGCGCGTTAATCAAGCGTTATGAAAAA
GAAGCCAAAGAAGAGGGCAAGAAAAGATCGTATGCCATTTTAGCGGAAGCGACAGCCCGTTTTGCGGGTAATTATGCGGC
AGAGAATTTAACAACTCGCATTGCTTTGCCTTGCTCAGATTATATCGGTCGCGTGATAGGCAAAGACGGAAAAAATATTG
AAGCGTTTAAAAAAGTCAGTGGGGTGGATATAGAATTTAGCGAAGGTAGCAGCGAATTGTATTTGTCCAGTTTCAATCTT
TATCGGCGTGAAGTAGCGAGCGAAACGCTTAAAATTTTAATAGAAGACGGCCGTATCCAGCCTAACAGGATTGAAGAAGT
TTATCATAGAGTCGCGCGCAACATGGAAAAAGAATTGCTTTCTGAAGGGGAGAGCGTGGTGCTAGAATTAGAGCTTGGGG
CTATGGAAGATGAGCTTAAAATTTTAATAGGCAAAATGCGTTATCGTTCTAGTTTTGGGCAAAACGCCTTACAGCATTCT
AAAGAAGTCGCTCTTTTAGCCGGCTTGATTGCAGAACAGCTTGAGGGGGATAAAAAACTCGCCAGAAGAGCCGGTATTTT
GCATGATATTGGTAAAGCGCTCACCCAAGAGCTTGGGAGAGATCATGTGAATTTAGGGGTTGAGGTGTGCAAGCGCCATA
AAGAAGATCCGGTTGTGATTAATGCGATTTATGCCCACCATGGGCATGAAGAGATCATGAGCGTAGAGTGTGCGAGCGTG
TGTGCGGCTGATGCGCTTTCAGCAGGGCGTCCTGGGGCTAGAAGAAAGAGCGATGAAGAATACGCTAAACGCATGCAAGC
TTTAGAAGAGATCGCGCTAGAATTTGATGGGGTGGAAAAGGCGTATGCGATGGAGAGCGGGCGAGAATTAAGAGTGATTG
TCAAATCCAACCAAGTCAGGGACAATCAAGTGCCTATTATTGCCAGAAAGATCGCTAAAAAGATAGAAGAGAGCGCTCAG
TATGTGGGCGAAGTGGGCGTGCAAGTGGTGCGAGAAAGCCGTTTCAAAACGACCGCTACACTCAAGCAATAA

Upstream 100 bases:

>100_bases
AAGAATAATAAAAGGAAACATTATGAGCAGCGGGTTAATTTACATTTCATTAGAAGTCTTAGTAGCGTGTTTGATTACCG
CTCTAGTCATGTATTATGTG

Downstream 100 bases:

>100_bases
TCAAGCCTTTTTCCCGCACCTTTTCCAAATGCCTTTAGAAAAAACTTTATAATAGATGAATGAGCGCAAAAAAGTTTCTG
ATGCGATCACTACAAAAATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKKIYYARGQTILKGASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLQTHFEKKEVHLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQCAVCKEAQAKALDAMLNYMAYTKDEIKNMVLEQLEEELEVQKSALIKRYEK
EAKEEGKKRSYAILAEATARFAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSGVDIEFSEGSSELYLSSFNL
YRREVASETLKILIEDGRIQPNRIEEVYHRVARNMEKELLSEGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLEGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEIMSVECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ

Sequences:

>Translated_503_residues
MKKIYYARGQTILKGASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLQTHFEKKEVHLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQCAVCKEAQAKALDAMLNYMAYTKDEIKNMVLEQLEEELEVQKSALIKRYEK
EAKEEGKKRSYAILAEATARFAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSGVDIEFSEGSSELYLSSFNL
YRREVASETLKILIEDGRIQPNRIEEVYHRVARNMEKELLSEGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLEGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEIMSVECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ
>Mature_503_residues
MKKIYYARGQTILKGASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLQTHFEKKEVHLKHLEAQHKEFVRD
EKRYLEKEKQELEKERQILEQEKENFKKQCAVCKEAQAKALDAMLNYMAYTKDEIKNMVLEQLEEELEVQKSALIKRYEK
EAKEEGKKRSYAILAEATARFAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSGVDIEFSEGSSELYLSSFNL
YRREVASETLKILIEDGRIQPNRIEEVYHRVARNMEKELLSEGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHS
KEVALLAGLIAEQLEGDKKLARRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEIMSVECASV
CAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
YVGEVGVQVVRESRFKTTATLKQ

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 57438; Mature: 57438

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYYARGQTILKGASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLQTHF
CCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EKKEVHLKHLEAQHKEFVRDEKRYLEKEKQELEKERQILEQEKENFKKQCAVCKEAQAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAMLNYMAYTKDEIKNMVLEQLEEELEVQKSALIKRYEKEAKEEGKKRSYAILAEATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSGVDIEFSEGSSELYLSSFNL
HHCCHHHHCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCEEHHHHHH
YRREVASETLKILIEDGRIQPNRIEEVYHRVARNMEKELLSEGESVVLELELGAMEDELK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
ILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLEGDKKLARRAGILHDIGKALTQELGR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
DHVNLGVEVCKRHKEDPVVINAIYAHHGHEEIMSVECASVCAADALSAGRPGARRKSDEE
HHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
YAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YVGEVGVQVVRESRFKTTATLKQ
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIYYARGQTILKGASAKAKLMEFQAKSFVEAEEMRMKSQECKLQQQYENKNLQLQTHF
CCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EKKEVHLKHLEAQHKEFVRDEKRYLEKEKQELEKERQILEQEKENFKKQCAVCKEAQAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAMLNYMAYTKDEIKNMVLEQLEEELEVQKSALIKRYEKEAKEEGKKRSYAILAEATAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSGVDIEFSEGSSELYLSSFNL
HHCCHHHHCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCEEHHHHHH
YRREVASETLKILIEDGRIQPNRIEEVYHRVARNMEKELLSEGESVVLELELGAMEDELK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
ILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLEGDKKLARRAGILHDIGKALTQELGR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
DHVNLGVEVCKRHKEDPVVINAIYAHHGHEEIMSVECASVCAADALSAGRPGARRKSDEE
HHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
YAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQ
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YVGEVGVQVVRESRFKTTATLKQ
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA