| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is secA [H]
Identifier: 188527369
GI number: 188527369
Start: 552368
End: 554965
Strand: Reverse
Name: secA [H]
Synonym: HPSH_02880
Alternate gene names: 188527369
Gene position: 554965-552368 (Counterclockwise)
Preceding gene: 188527371
Following gene: 188527368
Centisome position: 34.5
GC content: 39.88
Gene sequence:
>2598_bases ATGATAAAAGCAATAATTGGAAAAATCATTGGCACCAGAAACGATCGCTGGATCAAACAATACAAAAAAAAAGTTCTAGC TATCAACGCCTTAGAGCCCACTTATGAAAAAATGAGCGATGATGAGTTGCAAAACGCTTTTGAAGAATTAAAAAAACGAG TGCGATCCGTAGAAAAAGATTTGCAAGAAAAAACCCTTTTAGAAGTCTTACCAGAAAGTTTTGCCATCACTAGAGAAGCG AGCAAAAGGATCTTAAAGATGCGCCATTTTGATGTGCAACTCATTGGGGGCATGGTCTTAAACGATGGCAAAATCGCTGA AATGAAAACCGGTGAGGGCAAAACTTTAGTCGCTACTTTAGCGGTGGCTTTGAACGCTTTAAAGGGCGAGAGCGTGTATG TGGTAACCGTTAATGATTACCTAGCGCATAGGGATTCTAAAGAAATGGAGCCGTTGTATCATTTCTTAGGTTATAGCGTA GGCACGATCACTGCAAGCGTGCGAGATGATGATGAGCGATTGGAAATTTATTCTAAAGACATTGTTTATGGCACTAATAA TGAATTTGGCTTTGATTATCTAAGGGATAACATGAAATATTCTTTAGAGCATAAGGTGCAAAAATCCCATGCGTTTGCTA TTGTTGATGAAGTGGATTCCATTTTAATTGATGAAGCCAGAACCCCCTTAATCATTTCAGGGCCTGTGGATAGGCGCATG GAAAATTACAACAAGGCTGATGAAGTCGCTAAAAGCATGCAAGTGGAAATAGATTTCACCATAGATGAAAAAAACCGCAC GATTTTAATCACTGAAGAGGGGATTAAAAAAGCCGAAAACCTCTTTGGCGTGGATAATTTATACAAGATTGAAAACGCCG CCCTATCGCACCATTTAGACCAGGCTTTGAAAGCGAATTACCTCTTTTTTATTGATAAAGATTATATTGTAGCCAATAAT GAAGTGGTGATTGTAGATGAATTTACCGGCCGTTTGTCTGAGGGGAGGCGCTTTAGTGAGGGCTTGCATCAGGCTTTAGA GGCTAAAGAGGGCGTGAGCATTAAAGAAGAGAGCCAAACCTTAGCCGATATTACTTTCCAAAATTATTTTAGGATGTTTT CTAAACTCGCTGGCATGACAGGCACGGCTCAAACCGAAGCCACAGAATTTTTAGAAATCTATAATTTAGAAGTGGTGTCT ATCCCTACTAATCTAGCGATCAAGCGGAAAGATTTGAACGATTTGATCTATAAGAGTGAAAAAGAAAAATTTGACGCCGT GATCCTTAAGATTAAAGAGTTGCACGATAAGGGACAGCCGGTTTTAGTCGGCACGGCCAGCATTGAAAAGAGTGAAACCT TACACGCTTTACTCAAAAAAGAACGCATCCCTCACACTGTTTTAAACGCCAAGCAGCACACCAAAGAAGCTGAAATCATC AAAGACGCCGGGCTTAAAGGGGCGGTTACGATTGCGACTAACATGGCAGGCAGGGGCGTTGATATTAAACTCACTGATGA AATTAAAGAGCTTGGGGGGCTGTATATCATTGGCACTGAAAGGCATGAGAGCCGCAGGATTGACAACCAATTAAGGGGGC GAAGCGGGCGCCAAGGCGATCCGGGAACAAGCCAATTTTATTTGAGTTTAGAAGACAATCTGTTACGCATTTTTGGGAGC GATAGGATTAAGGGGGTGATGGAAAAATTAGGGCTTAAAGACGGCGAACACATTGAATCAAAGCTTGTTACAAGAGCGGT GGAAAACGCACAAAAAAAAGTGGAGAACTTGCATTTTGAAAGCCGTAAGCATTTGTTGGAATACGATGATGTCGCTAATG AGCAACGAAAAAGCGTGTATAAATTTAGAGATGAACTATTAGATGTCAATTACGATATTAGCGCTAAAATCGCTGAAAAC AGAGAATACGCGCTCAATCAAATCTTTTCTAAACTCAAAGCCTTTGACCATCAAAACTTGTCTGAAGAGGAACTTTTAGG GCTTAAAAACATCTTAAAAGAAGATTTTAACGCCCATGTTGGATTAGAAGATTTAAAAAAAGCCTCTCCTATTGAAAATT TTATCGCTGAAAAATTAAAAAGCGATTATGAAAACAAAATGAAAGTTTTGGATAGCGAACAAAGAAGCCGGATTGAACGC ATCGTGTATTTGCAGATTTTAGACAACGCATGGCGAGAGCACCTTTATACGATGGATAATCTCAAAACCGGTATTAATTT AAGAGGCTATAACCAAAAAGACCCTCTTGTAGAATACAAAAAAGAGAGTTACAACCTTTTCTTAGAACTCATTGAAGACA TTAAAATGGAAGCGATCAAAACCTTTTCTAAGATCCAGTTTGAAGATGAGCAAGATTCTAGCGATGCGGAGCGTTATTTG GATAACTTTAGCGAAGAAAGAGAGCATGAGAGCGTAACTTACCGCCATGAAGAAGCCTTAGATGAAGATTTGAATGTGGC CATGAAAGCTTTCGCTAAAACCCCTAAAAGGAACGAACCTTGCCCTTGTGGGAGTGGCAAAAAATATAAAGATTGTTGCG CTAAAAGCGGGCCTAAAAAGGGCTTATTTGCCAAATAG
Upstream 100 bases:
>100_bases TTACATGACTTTTATTTTATCCATGCTAAAATGGGATTAAAAACTGACGCTTTAATAAAATAAATGGGATTAAAGCACTC TTAATAAGGTTATTACCACT
Downstream 100 bases:
>100_bases ATCGTTGATTTTTTTCCTTATCAAGCGTTATTTGCGTTTTGATAAAAGCCAGCCTTTTATTAGCATCACCGCTTTGTTGG CTTTTTTTGGCGTGGCGGTT
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 865; Mature: 865
Protein sequence:
>865_residues MIKAIIGKIIGTRNDRWIKQYKKKVLAINALEPTYEKMSDDELQNAFEELKKRVRSVEKDLQEKTLLEVLPESFAITREA SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM ENYNKADEVAKSMQVEIDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVS IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAEN REYALNQIFSKLKAFDHQNLSEEELLGLKNILKEDFNAHVGLEDLKKASPIENFIAEKLKSDYENKMKVLDSEQRSRIER IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLELIEDIKMEAIKTFSKIQFEDEQDSSDAERYL DNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEPCPCGSGKKYKDCCAKSGPKKGLFAK
Sequences:
>Translated_865_residues MIKAIIGKIIGTRNDRWIKQYKKKVLAINALEPTYEKMSDDELQNAFEELKKRVRSVEKDLQEKTLLEVLPESFAITREA SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM ENYNKADEVAKSMQVEIDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVS IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAEN REYALNQIFSKLKAFDHQNLSEEELLGLKNILKEDFNAHVGLEDLKKASPIENFIAEKLKSDYENKMKVLDSEQRSRIER IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLELIEDIKMEAIKTFSKIQFEDEQDSSDAERYL DNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEPCPCGSGKKYKDCCAKSGPKKGLFAK >Mature_865_residues MIKAIIGKIIGTRNDRWIKQYKKKVLAINALEPTYEKMSDDELQNAFEELKKRVRSVEKDLQEKTLLEVLPESFAITREA SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM ENYNKADEVAKSMQVEIDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVS IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAEN REYALNQIFSKLKAFDHQNLSEEELLGLKNILKEDFNAHVGLEDLKKASPIENFIAEKLKSDYENKMKVLDSEQRSRIER IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLELIEDIKMEAIKTFSKIQFEDEQDSSDAERYL DNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEPCPCGSGKKYKDCCAKSGPKKGLFAK
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=914, Percent_Identity=49.0153172866521, Blast_Score=809, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 99046; Mature: 99046
Theoretical pI: Translated: 5.72; Mature: 5.72
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIKAIIGKIIGTRNDRWIKQYKKKVLAINALEPTYEKMSDDELQNAFEELKKRVRSVEKD CHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH LQEKTLLEVLPESFAITREASKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEECCCCEEEEECCCCCHHHHHH AVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSVGTITASVRDDDERLEIYSKD HHHHHHHCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCHHHHEEEECCCCHHHHHEEECC IVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM EEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHH ENYNKADEVAKSMQVEIDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLD HHCCHHHHHHHHEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH QALKANYLFFIDKDYIVANNEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQT HHHHCCEEEEEECCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHH LADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVSIPTNLAIKRKDLNDLIYKSE HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHCH KEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGD HHCCCCCEEEEEECCCCCCCEEEEHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCC PGTSQFYLSLEDNLLRIFGSDRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFE CCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH SRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAENREYALNQIFSKLKAFDHQNL HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC SEEELLGLKNILKEDFNAHVGLEDLKKASPIENFIAEKLKSDYENKMKVLDSEQRSRIER CHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLELIEDIKMEAIK HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH TFSKIQFEDEQDSSDAERYLDNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEP HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC CPCGSGKKYKDCCAKSGPKKGLFAK CCCCCCCCHHHHHHCCCCCCCCCCC >Mature Secondary Structure MIKAIIGKIIGTRNDRWIKQYKKKVLAINALEPTYEKMSDDELQNAFEELKKRVRSVEKD CHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH LQEKTLLEVLPESFAITREASKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEECCCCEEEEECCCCCHHHHHH AVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSVGTITASVRDDDERLEIYSKD HHHHHHHCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCHHHHEEEECCCCHHHHHEEECC IVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM EEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHH ENYNKADEVAKSMQVEIDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLD HHCCHHHHHHHHEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH QALKANYLFFIDKDYIVANNEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQT HHHHCCEEEEEECCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHH LADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVSIPTNLAIKRKDLNDLIYKSE HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHCH KEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGD HHCCCCCEEEEEECCCCCCCEEEEHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCC PGTSQFYLSLEDNLLRIFGSDRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFE CCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH SRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAENREYALNQIFSKLKAFDHQNL HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC SEEELLGLKNILKEDFNAHVGLEDLKKASPIENFIAEKLKSDYENKMKVLDSEQRSRIER CHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLELIEDIKMEAIK HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH TFSKIQFEDEQDSSDAERYLDNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEP HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC CPCGSGKKYKDCCAKSGPKKGLFAK CCCCCCCCHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA