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The map label for this gene is lolC [H]

Identifier: 188527368

GI number: 188527368

Start: 551146

End: 552432

Strand: Reverse

Name: lolC [H]

Synonym: HPSH_02875

Alternate gene names: 188527368

Gene position: 552432-551146 (Counterclockwise)

Preceding gene: 188527369

Following gene: 188527367

Centisome position: 34.34

GC content: 39.55

Gene sequence:

>1287_bases
GTGGCAAAAAATATAAAGATTGTTGCGCTAAAAGCGGGCCTAAAAAGGGCTTATTTGCCAAATAGATCGTTGATTTTTTT
CCTTATCAAGCGTTATTTGCGTTTTGATAAAAGCCAGCCTTTTATTAGCATCACCGCTTTGTTGGCTTTTTTTGGCGTGG
CGGTTGGCGTGATGGTTTTAATTGTGGCTATGGCGATCATGAACGGCATGAGTAAGGAATTTGAAAAAAAGCTTTTTGTG
ATGAACTACCCCTTAACGCTCTATACCACAAGCCCTTATGGGATCAGCGAAGAAGTGGTTCAAGCTTTAGAAAAAAAGTT
CCCTAATTTGCTTTTTAGCCCCTATTTGCAAACTCAAAGCCTGATTAAAAGCGCTCATTCCATGAATGGTGGCGTGGTGT
TTGGGGTTGATTTTTCTAAAGAAAGGCGTATCAATGAAGTTTTAAACGACGCTTTAAAAAACACCAATGAAAACGATCTT
TTTAAAAACCCTTTTAATTTGATCGTGGGGAAAAGCTTGAGATACAGCTTGAATTTAGATCTCAATCAAAAAGCCGATTT
GTTTTTTACCGAATTAGAGCCAACAGGCCTCACGCTCTCCCCTATCATGAAGCGTTTTACTATCAAAGGCGATTTTGATT
CAGGGCTAAAATCTTACGACATGAGCTACATGTATTCTAGCCTTCAAGCCATAAGCGCGATCAGGAGATTGCCCTTAGGG
CTTTATGATGGGGTGCATGTCTATTCTAAAACGCCCATGAAGGATATTGAAAATTTACGCAACGCTTTAAAAACCATCAA
CCACCATGGCATAGGCATTGAAGGGTGGTGGCAACAAAACGGGAATTTTTTCTCGGCTATGGAATTAGAAAAAAGAGCGT
TATTCATTGTGCTCATGCTCATTATTTTAATGGCGTCTTTGAATATCATCAGCTCGCTTTTAATGGTGGTGATGAACAGG
CGTAAAGAAATCGCCCTACTCTTTAGCATGGGGAGCAGCCAAAAAGAAATCCAAAAAACCTTTTTTTATTTGGGCAATAT
CATTGGTTTAGGCGGTGTGGTGCTTGGGGTGATTTTAGCGTTTTTAAGCATGTATCTTTTAAGCGTGTTCCCTATCATCT
CGCTCCCAGCAGATGTCTATGGCATTAACACTTTGCCTTTGGATCTGTCTTTAATGGATTTTATGCTCACTCTAATAGGC
TCTATCATTATCGTAGCCCTTTCTTCTTATTACCCGTCTAAAAAAGCTTCTCATATTGACGCTTTAAGCGTGTTAAGGAA
TGAATAA

Upstream 100 bases:

>100_bases
GTAACTTACCGCCATGAAGAAGCCTTAGATGAAGATTTGAATGTGGCCATGAAAGCTTTCGCTAAAACCCCTAAAAGGAA
CGAACCTTGCCCTTGTGGGA

Downstream 100 bases:

>100_bases
ATTAAAAAATTAAATAATATTGAGATTAAATAAGGCTTTGAGTGTCTATATTTGACTGACAAAGAAAAATTTTATCCTTA
AAAATTAAAAAAAACAATAA

Product: lipoprotein release system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MAKNIKIVALKAGLKRAYLPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFV
MNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNENDL
FKNPFNLIVGKSLRYSLNLDLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYSSLQAISAIRRLPLG
LYDGVHVYSKTPMKDIENLRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNR
RKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVVLGVILAFLSMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIG
SIIIVALSSYYPSKKASHIDALSVLRNE

Sequences:

>Translated_428_residues
MAKNIKIVALKAGLKRAYLPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFV
MNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNENDL
FKNPFNLIVGKSLRYSLNLDLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYSSLQAISAIRRLPLG
LYDGVHVYSKTPMKDIENLRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNR
RKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVVLGVILAFLSMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIG
SIIIVALSSYYPSKKASHIDALSVLRNE
>Mature_427_residues
AKNIKIVALKAGLKRAYLPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFVM
NYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNENDLF
KNPFNLIVGKSLRYSLNLDLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYSSLQAISAIRRLPLGL
YDGVHVYSKTPMKDIENLRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNRR
KEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVVLGVILAFLSMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGS
IIIVALSSYYPSKKASHIDALSVLRNE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=407, Percent_Identity=24.0786240786241, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787360, Length=412, Percent_Identity=23.3009708737864, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48113; Mature: 47982

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNIKIVALKAGLKRAYLPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVL
CCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IVAMAIMNGMSKEFEKKLFVMNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQS
HHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
LIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNENDLFKNPFNLIVGKSLRYSLNLD
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEEECC
LNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYSSLQAISAIRRLPLG
CCCCCCEEEEECCCCCCCHHHHHHHHEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
LYDGVHVYSKTPMKDIENLRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLML
CCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHH
IILMASLNIISSLLMVVMNRRKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVVLGVILA
HHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGSIIIVALSSYYPSKKASHID
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALSVLRNE
HHHHHHCC
>Mature Secondary Structure 
AKNIKIVALKAGLKRAYLPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVL
CCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IVAMAIMNGMSKEFEKKLFVMNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQS
HHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
LIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNENDLFKNPFNLIVGKSLRYSLNLD
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEEECC
LNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYSSLQAISAIRRLPLG
CCCCCCEEEEECCCCCCCHHHHHHHHEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
LYDGVHVYSKTPMKDIENLRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLML
CCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHH
IILMASLNIISSLLMVVMNRRKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVVLGVILA
HHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGSIIIVALSSYYPSKKASHID
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALSVLRNE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]