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The map label for this gene is moaC

Identifier: 188527358

GI number: 188527358

Start: 539393

End: 539869

Strand: Direct

Name: moaC

Synonym: HPSH_02825

Alternate gene names: 188527358

Gene position: 539393-539869 (Clockwise)

Preceding gene: 188527357

Following gene: 188527359

Centisome position: 33.53

GC content: 40.25

Gene sequence:

>477_bases
ATGCCGCTCACTCATTTGAATGAAGAAAATCAGCCTAAAATGGTGGATATAGGGGATAAGGAAACCACTGAAAGAATCGC
TCTAGCAAGCGGTCGTATCAGCATGAATAAAGAGGCTTATGACGCTATTGTTAATCATTGCGTCAAAAAGGGTCCGGTGT
TACAGACTGCTATTATTGCTGGGATTATGGGGGCTAAAAAGACAAGCGAACTCATTCCCATGTGCCATTCAATCATGCTC
AATGGGGTGGATATTGATATTTTAGAAGAAAAAGAAACTCATAGTTTTAAACTCTATGCGAGAGTCAAAACTCAAGCTAA
AACGGGCGTAGAAATGGAAGCGCTAATGAGTGTGAGTATAGGGCTTTTAACCATTTATGACATGGTGAAAGCCATTGATA
AGAGCATGACAATTAGCGGTGTGATGTTGGAGCATAAAAGTGGAGGCAAAAGTGGGGATTATAACGCTAAAAAATAG

Upstream 100 bases:

>100_bases
TTCCAGCGATTCCTTATTGCGTGGATTTGATTTTAGGAAATTATATGCAAGTGAATGAAAAAAACATTCAAGCGTTTCGC
CCCAAACAATAAGGTAAAAA

Downstream 100 bases:

>100_bases
AAAAAGACTGATAATCTAAAGATGTTAGGGTAAAATAACATTTTGACAACAAAAGCGTGTTGGTTGCTTCGGGTTTGTTG
TTATAGAAGTCTAAAATATT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIVNHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHSIML
NGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Sequences:

>Translated_158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIVNHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHSIML
NGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
>Mature_157_residues
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIVNHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHSIMLN
GVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=44.7368421052632, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.2818791946309, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=45.2702702702703, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=46.7153284671533, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17281; Mature: 17150

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIVNHCVKKGPVLQTAIIA
CCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
GIMGAKKTSELIPMCHSIMLNGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIVNHCVKKGPVLQTAIIA
CCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
GIMGAKKTSELIPMCHSIMLNGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA