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The map label for this gene is mogA

Identifier: 188527357

GI number: 188527357

Start: 538854

End: 539384

Strand: Direct

Name: mogA

Synonym: HPSH_02820

Alternate gene names: 188527357

Gene position: 538854-539384 (Clockwise)

Preceding gene: 188527356

Following gene: 188527358

Centisome position: 33.5

GC content: 39.74

Gene sequence:

>531_bases
ATGCAAACGATTCATATAGGCGTTTTGAGCGCGAGCGATAGAGCGTCAAAAGGGATTTATGAAGATTTAAGCGGTAAAGC
GATACAAGAAGTGTTGAGCGAATATCTGCTTAATCCTTTAGAATTTCATTACGAAATTGTCGCTGATGAAAGGGATTTAA
TTGAAAAATCGCTGATTAAAATGTGCGATGAATACCAATGCGATCTAGTCGTTACTACAGGAGGCACAGGCCCTGCTCTA
AGAGATATAACCCCAGAAGCCACAGAAAAAGTGTGCCAAAAAATGCTTCCTGGTTTTGGAGAGCTTATGCGAATGACTAG
TTTAAAATATGTGCCTACAGCGATTCTATCGCGCCAGAGCGCTGGTGTTAGGAATAAGAGTTTGATTGTCAATCTCCCTG
GTAAGCCAAAAAGTATTAGAGAATGCTTAGAAGCGGTTTTTCCAGCGATTCCTTATTGCGTGGATTTGATTTTAGGAAAT
TATATGCAAGTGAATGAAAAAAACATTCAAGCGTTTCGCCCCAAACAATAA

Upstream 100 bases:

>100_bases
TATTTGGAAATACGATTTAATCCACAATAAACGCATCTACGCTAAAGAAAGAAGCCACCTTTTAAAAGGGAGTGGGCTTT
TAGCTTAAAAAGGAGTTGAA

Downstream 100 bases:

>100_bases
GGTAAAAAATGCCGCTCACTCATTTGAATGAAGAAAATCAGCCTAAAATGGTGGATATAGGGGATAAGGAAACCACTGAA
AGAATCGCTCTAGCAAGCGG

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MQTIHIGVLSASDRASKGIYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIKMCDEYQCDLVVTTGGTGPAL
RDITPEATEKVCQKMLPGFGELMRMTSLKYVPTAILSRQSAGVRNKSLIVNLPGKPKSIRECLEAVFPAIPYCVDLILGN
YMQVNEKNIQAFRPKQ

Sequences:

>Translated_176_residues
MQTIHIGVLSASDRASKGIYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIKMCDEYQCDLVVTTGGTGPAL
RDITPEATEKVCQKMLPGFGELMRMTSLKYVPTAILSRQSAGVRNKSLIVNLPGKPKSIRECLEAVFPAIPYCVDLILGN
YMQVNEKNIQAFRPKQ
>Mature_176_residues
MQTIHIGVLSASDRASKGIYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIKMCDEYQCDLVVTTGGTGPAL
RDITPEATEKVCQKMLPGFGELMRMTSLKYVPTAILSRQSAGVRNKSLIVNLPGKPKSIRECLEAVFPAIPYCVDLILGN
YMQVNEKNIQAFRPKQ

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=164, Percent_Identity=41.4634146341463, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI66932975, Length=164, Percent_Identity=41.4634146341463, Blast_Score=133, Evalue=9e-32,
Organism=Escherichia coli, GI1786190, Length=187, Percent_Identity=47.5935828877005, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI1787000, Length=142, Percent_Identity=32.3943661971831, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=157, Percent_Identity=34.3949044585987, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136978, Length=157, Percent_Identity=36.3057324840764, Blast_Score=106, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24638841, Length=157, Percent_Identity=36.3057324840764, Blast_Score=106, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19623; Mature: 19623

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIHIGVLSASDRASKGIYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIK
CCEEEEEEEECCCHHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
MCDEYQCDLVVTTGGTGPALRDITPEATEKVCQKMLPGFGELMRMTSLKYVPTAILSRQS
HHCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
AGVRNKSLIVNLPGKPKSIRECLEAVFPAIPYCVDLILGNYMQVNEKNIQAFRPKQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MQTIHIGVLSASDRASKGIYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIK
CCEEEEEEEECCCHHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
MCDEYQCDLVVTTGGTGPALRDITPEATEKVCQKMLPGFGELMRMTSLKYVPTAILSRQS
HHCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
AGVRNKSLIVNLPGKPKSIRECLEAVFPAIPYCVDLILGNYMQVNEKNIQAFRPKQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]