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The map label for this gene is fabH [H]

Identifier: 188527007

GI number: 188527007

Start: 191785

End: 192780

Strand: Direct

Name: fabH [H]

Synonym: HPSH_01035

Alternate gene names: 188527007

Gene position: 191785-192780 (Clockwise)

Preceding gene: 188527006

Following gene: 188527008

Centisome position: 11.92

GC content: 43.17

Gene sequence:

>996_bases
ATGGAATTTTACGCCTCTCTTAAATCCATTGCGATGCATGTTCCAAGCGAGCGTGTGAAAAATGCAGAGTTCCAGCAATT
TTTGGATACCAGCGATGAGTGGATAGAAAAAAGGACCGGTATCAAAGAACGCCGTTTCGCTAACGATGAAGAAAAAAGCA
GCGATTTAGGGGTAATAGCGGCTAAACAAGCCATAGAGAGAGCGCATTTAACCCCAAAAGACATTGATTTGGTGGTTGTA
GCGACTTTAAGCCCTGATTTTTTAGCCATGCCTTCAACCGCTTGCGTGTTGAGCGCGAAATTAGGGATTGAAAACAAGCC
GGCGTTTGATATTTCAGCCGCTTGCACGGGTTTTATTTATTTATTATCGGTGGCTAAGGCTTATGTTGAGAGCGGGATGT
GCGAAAATGTGCTGATTGTGGGAGCAGAAAAAACGAGCAGCGTGTTAGATTTTAAAGACAGGGGGACTTGTATTTTATTT
GGCGATGGGGCTGGGGCGTGTGTGATAGGCAGAACCAAGCGTTTAAAAGAGAGCGTTTTAGATGTGCAAATTTCAGCGAA
CGGGAATTTTTCTAATTATCTCTATACGCCAAGAACTCTAAAACCCACGCCCTTTAACGCTAAAGAAGAAGCTTCAGAGC
CTTTTTTACGCATGAAAGGCAATGAAGTGTTTAAACTAGCGGTAAAAACGCTTTTAAAAGATGTGGAAATGATCTTAGAA
AAAAACGCTCTCAAACCTGAAGATGTGCGTTTGTTTATCCCGCATCAAGCTAATTTTAGGATCATCCAAGCGGTGCGGGA
GCATTTGGATTTTAAAGATGAGCAAGTGGTTTTAACCGTGCATAAATACGGCAACACTTCGGCAGCCAGTATCCCTATGG
CCATGTGTGAAGCTTATGAAGAGGGGCGTTTGAAAAAGGGCGATTTAATGCTTTTAGATGCTTTTGGTGGGGGATTGACT
TGGGGTTCAGCGTTGGTGTATTTTGGAGGAAGTTAG

Upstream 100 bases:

>100_bases
GTTTGAGGATCACTAAGGCGTTTGAGAGCTTGAAGCCTAGCGTTTCTGTGCCTCAAAGTGATCAGCAAGACGCTTAAAAA
TAACTATGTAAAGGGATTGA

Downstream 100 bases:

>100_bases
GAAAAGATTGAAGGAGTATTGATGAAAAAGATGATTTTTTTATTTTTAGTGGTGTTGGGGGGTTTAGAAGCGCAAAGCAC
TTATTGCAGCGATCATTGCG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIAAKQAIERAHLTPKDIDLVVV
ATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILF
GDGAGACVIGRTKRLKESVLDVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLRMKGNEVFKLAVKTLLKDVEMILE
KNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYEEGRLKKGDLMLLDAFGGGLT
WGSALVYFGGS

Sequences:

>Translated_331_residues
MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIAAKQAIERAHLTPKDIDLVVV
ATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILF
GDGAGACVIGRTKRLKESVLDVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLRMKGNEVFKLAVKTLLKDVEMILE
KNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYEEGRLKKGDLMLLDAFGGGLT
WGSALVYFGGS
>Mature_331_residues
MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIAAKQAIERAHLTPKDIDLVVV
ATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILF
GDGAGACVIGRTKRLKESVLDVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLRMKGNEVFKLAVKTLLKDVEMILE
KNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYEEGRLKKGDLMLLDAFGGGLT
WGSALVYFGGS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=43.558282208589, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36494; Mature: 36494

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIA
CCHHHHHHHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCCHHH
AKQAIERAHLTPKDIDLVVVATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIY
HHHHHHHHCCCCCCCCEEEEEECCCCCEECCCHHEEEEEECCCCCCCCCCHHHHHHHHHH
LLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILFGDGAGACVIGRTKRLKESVL
HHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEECCCCEEEECCHHHHHHHHE
DVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLRMKGNEVFKLAVKTLLKDVEMILE
EEEEECCCCCCCEEECCCCCCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
KNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYE
HCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
EGRLKKGDLMLLDAFGGGLTWGSALVYFGGS
HCCCCCCCEEEEECCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIA
CCHHHHHHHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCCHHH
AKQAIERAHLTPKDIDLVVVATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIY
HHHHHHHHCCCCCCCCEEEEEECCCCCEECCCHHEEEEEECCCCCCCCCCHHHHHHHHHH
LLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILFGDGAGACVIGRTKRLKESVL
HHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEECCCCEEEECCHHHHHHHHE
DVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLRMKGNEVFKLAVKTLLKDVEMILE
EEEEECCCCCCCEEECCCCCCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
KNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYE
HCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
EGRLKKGDLMLLDAFGGGLTWGSALVYFGGS
HCCCCCCCEEEEECCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA