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The map label for this gene is efp [H]

Identifier: 188526981

GI number: 188526981

Start: 168530

End: 169093

Strand: Direct

Name: efp [H]

Synonym: HPSH_00890

Alternate gene names: 188526981

Gene position: 168530-169093 (Clockwise)

Preceding gene: 188526980

Following gene: 188526982

Centisome position: 10.48

GC content: 45.39

Gene sequence:

>564_bases
ATGGCAATTGGGATGAGTGAGCTCAAAAAGGGCTTGAAAATTGAATTGGGCGGTGTGCCTTATAGGATCGTAGAATACCA
ACATGTCAAGCCCGGCAAGGGTGCGGCTTTTGTGCGCGCGAAAATCAAGTCGTTTTTAGATGGCAAGGTGATTGAAAAGA
CTTTCCATGCGGGGGATAAGTGCGAAGAGCCTAATCTGGTTGAAAAAACGATGCAATACCTTTATCACGATGGCGATACA
TACCAATTCATGGACATAGAGAGCTATGAGCAAATCGCTTTGAACGACTCTCAAGTGGGCGAGGCTTCTAAATGGATGCT
AGACGGCATGCAAGTGCAGGTTTTATTGCATAATGACAAGGCGATTTCAGTGGACGTGCCGCAAGTTGTGGCTCTAAAGA
TTGTAGAAACAGCCCCTAATTTTAAGGGCGATACTTCAAGCGCGAGCAAAAAACCAGCGACTTTAGAAACCGGTGCGGTC
GTGCAAGTGCCTTTCCATGTTTTAGAGGGTGAGATCATTAAGGTCAATACGGAAACAGAAGAGTATCTTGAAAAGGTGAA
GTGA

Upstream 100 bases:

>100_bases
TTTTTCTCCGGCCCAATTAGCGCTTAAAAATGTGGTCAAAGAGCGCATGAAACTTTTGGGCAGCGCTAATAAAATTTAAC
CAACAAGGAAAGAGTGTAAC

Downstream 100 bases:

>100_bases
GATTATCTTTTTATTGAGTTAGCGCTTTAGGCACAGCTTTTTTGTCATAAGGGGTTGTTACTAGCCCCTTATTTGGGCTT
TGTTTAATGAGTTTTATTTA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDT
YQFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAV
VQVPFHVLEGEIIKVNTETEEYLEKVK

Sequences:

>Translated_187_residues
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDT
YQFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAV
VQVPFHVLEGEIIKVNTETEEYLEKVK
>Mature_186_residues
AIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDTY
QFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVV
QVPFHVLEGEIIKVNTETEEYLEKVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=45.0549450549451, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=31.5217391304348, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20788; Mature: 20657

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLVEKTMQYLYHDGDTYQFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDK
CCCCCHHHHHHHHHHCCCCEEEEEECCCHHHEECCCCCCCCHHHHHHCCEEEEEEEECCC
AISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGEIIKVNTETE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHCCEEEEEECCHH
EYLEKVK
HHHHHCC
>Mature Secondary Structure 
AIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDK
CCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCC
CEEPNLVEKTMQYLYHDGDTYQFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDK
CCCCCHHHHHHHHHHCCCCEEEEEECCCHHHEECCCCCCCCHHHHHHCCEEEEEEEECCC
AISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGEIIKVNTETE
EEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEHHHHCCEEEEEECCHH
EYLEKVK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA