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The map label for this gene is sdaC [H]

Identifier: 188526936

GI number: 188526936

Start: 128615

End: 129856

Strand: Reverse

Name: sdaC [H]

Synonym: HPSH_00665

Alternate gene names: 188526936

Gene position: 129856-128615 (Counterclockwise)

Preceding gene: 188526940

Following gene: 188526935

Centisome position: 8.07

GC content: 38.81

Gene sequence:

>1242_bases
ATGGCACAAGGAAAAGCGCTTATAAGAGATCCTAAAAAACTCAACGCGTTTGATTTGCGTTGGATGGCGTCCTTATTTGG
CACGGCGGTGGGGGCTGGGATTTTATTTTTGCCTATTAGAGCCGGTGGGCATGGGATATGGGCTATTGTGGTGATGAGCG
CGATCATATTCCCTTTAACTTATCTGGGGCATAGAGCTTTAGCTTATTTCATAGGATCTAAAGATAAAGAAGACATTACC
ATGGTCGTTCGCTCTCATTTTGGCGCTCAATGGGGTTTTCTTATCACTTTGCTTTATTTCTTTGCGATTTATCCTATTTG
TTTGGCTTATGGGGTGGGTATCACTAATGTGTTTGATCATTTCTTCACTAACCAGTTGCATTTAGCGCCTTTCCATCGGG
GCTTATTGGCTGTAGCGTTAGTCTCTTTAATGATGTTGGTGATGGTTTTTAACGCTACGATTGTTACGCGCATTTGTAAC
GCTTTAGTGTATCCTTTATGCTTGATTTTATTGCTTTTTTCTTTGTATCTTATCCCTTATTGGCAGGGCGCTAACCTTTT
TGTGATGCCGAGTTTTAAAGAATTTGTGTTAGCTGTTTGGCTAACCTTACCGGTGCTTGTGTTTTCATTCAACCATAGCC
CCATCATTTCAACCTTCACTCAAAATGTGGAAAAAGAATACGGCGCTTTCAAAGAGTATAAACTCAATCAAATTGAATTA
GGGACATCGCTGATGCTTTTAGGGTTTGTGATGTTTTTTGTGTTTTCGTGCGTCATGTGCTTGAATGCTGATGATTTTGT
GAAAGCAAGGGAACAAAATATCCCCATTTTAAGCTATTTTGCTAACACTTTAAACAACCCTTTAATCAATTATGCGGGGC
CTGTGGTGGCTTTTTTAGCGATTTTTTCATCTTTTTTTGGGCATTATTATGGGGCTAAGGAGGGTTTAGAAGGCATTATC
ATTCAAAGTTTAAAACTGAAAAAAGCTTCTAAAACCCTAAGCGTTAGCGTAACGATTTTTTTATGGCTGACTATCACGCT
TGTGGCTTATATTAACCCTAATATCTTGGATTTTATTGAAAATTTAGGCGGCCCCATTATCGCACTCATTCTGTTTGTGA
TGCCTATGATAGCTTTTTATAGCATTTCTAGTCTGAAGCGTTTTAGAAACCTTAAAGTGGATATTTTTGTGTTTGTTTTT
GGGAGCTTGACGGCTTTGAGCGTGTTTTTAGGACTATTTTAA

Upstream 100 bases:

>100_bases
GCGCTAAAAACCACCCCCCTAATCTCAAAAAACCCCAATCATAAAAAGCTTTATGCTACAATGAGAACTCTTTAACACGA
TAAAAAGGCGGTTTAATAGC

Downstream 100 bases:

>100_bases
TGGCTAGTTTTTCTATTTTATCCATTTTTAAAATCGGCGTGGGGCCTAGCTCTTCACACACTATAGGGCCTATGAAAGCT
GGAGCGAGATTTTGCGGGTT

Product: hypothetical protein

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAQGKALIRDPKKLNAFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLTYLGHRALAYFIGSKDKEDIT
MVVRSHFGAQWGFLITLLYFFAIYPICLAYGVGITNVFDHFFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICN
ALVYPLCLILLLFSLYLIPYWQGANLFVMPSFKEFVLAVWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
GTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGII
IQSLKLKKASKTLSVSVTIFLWLTITLVAYINPNILDFIENLGGPIIALILFVMPMIAFYSISSLKRFRNLKVDIFVFVF
GSLTALSVFLGLF

Sequences:

>Translated_413_residues
MAQGKALIRDPKKLNAFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLTYLGHRALAYFIGSKDKEDIT
MVVRSHFGAQWGFLITLLYFFAIYPICLAYGVGITNVFDHFFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICN
ALVYPLCLILLLFSLYLIPYWQGANLFVMPSFKEFVLAVWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
GTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGII
IQSLKLKKASKTLSVSVTIFLWLTITLVAYINPNILDFIENLGGPIIALILFVMPMIAFYSISSLKRFRNLKVDIFVFVF
GSLTALSVFLGLF
>Mature_412_residues
AQGKALIRDPKKLNAFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLTYLGHRALAYFIGSKDKEDITM
VVRSHFGAQWGFLITLLYFFAIYPICLAYGVGITNVFDHFFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICNA
LVYPLCLILLLFSLYLIPYWQGANLFVMPSFKEFVLAVWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIELG
TSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGIII
QSLKLKKASKTLSVSVTIFLWLTITLVAYINPNILDFIENLGGPIIALILFVMPMIAFYSISSLKRFRNLKVDIFVFVFG
SLTALSVFLGLF

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=407, Percent_Identity=43.980343980344, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI1789504, Length=443, Percent_Identity=39.5033860045147, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1789211, Length=380, Percent_Identity=35.2631578947368, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789961, Length=412, Percent_Identity=25.2427184466019, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI145693183, Length=422, Percent_Identity=25.1184834123223, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46289; Mature: 46158

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGKALIRDPKKLNAFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLT
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YLGHRALAYFIGSKDKEDITMVVRSHFGAQWGFLITLLYFFAIYPICLAYGVGITNVFDH
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICNALVYPLCLILLLFSLYLIPY
HHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQGANLFVMPSFKEFVLAVWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
CCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHH
GTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
IFSSFFGHYYGAKEGLEGIIIQSLKLKKASKTLSVSVTIFLWLTITLVAYINPNILDFIE
HHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NLGGPIIALILFVMPMIAFYSISSLKRFRNLKVDIFVFVFGSLTALSVFLGLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQGKALIRDPKKLNAFDLRWMASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLT
CCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YLGHRALAYFIGSKDKEDITMVVRSHFGAQWGFLITLLYFFAIYPICLAYGVGITNVFDH
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICNALVYPLCLILLLFSLYLIPY
HHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WQGANLFVMPSFKEFVLAVWLTLPVLVFSFNHSPIISTFTQNVEKEYGAFKEYKLNQIEL
CCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHH
GTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
IFSSFFGHYYGAKEGLEGIIIQSLKLKKASKTLSVSVTIFLWLTITLVAYINPNILDFIE
HHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NLGGPIIALILFVMPMIAFYSISSLKRFRNLKVDIFVFVFGSLTALSVFLGLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]