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The map label for this gene is infC

Identifier: 188526927

GI number: 188526927

Start: 122024

End: 122635

Strand: Direct

Name: infC

Synonym: HPSH_00620

Alternate gene names: 188526927

Gene position: 122024-122635 (Clockwise)

Preceding gene: 188526926

Following gene: 188526928

Centisome position: 7.59

GC content: 38.73

Gene sequence:

>612_bases
TTGAGCAGAAACGAAATGTTGTTAAACGGAGATATTAATTTTAAAGAAGTGCGTTGCGTGGGCGATAATGGCGAAGTGTA
TGGGATCATTTCTTCCAAAGAAGCGCTCAATATCGCTCAAAATTTAGGTTTGGATTTGGTTTTGATTTCAGCGAGCGCGA
AACCTCCCGTGTGTAAGGTGATGGATTATAATAAATTCCGCTACCAAAATGAAAAGAAAATCAAGGAAGCCAAGAAAAAG
CAAAAGCAAATTGAAATCAAAGAGATCAAGCTTTCCACTCAAATCGCGCAGAACGATATTAACTACAAAGTCAAGCATGC
GAGAGAATTTATTGAATCCAATAAGCATGTCAAATTCAAAGTGGTTTTAAAGGGTAGGGAGAGTCAAAACTCAAAAGCCG
GGCTTGATGTGCTTTTTAGAGTCCAAACGATGATGCAAGATTTAGCCAACCCTGAAAAAGAGCCAAAAACCGAGGGGCGT
TTTGTTTCATGGATGTTTGTGCCTAAGGCTAAAGAAGCCCCCAAGAACGAAAAGAAAACCAAGGAAAATAACCCGCCTTT
TAATCGTATTAACCTTATGAAAGGAGAAAATCATGCCAAAAATGAAGACTAA

Upstream 100 bases:

>100_bases
AAATTTTATCCATTAGAGACAGAGAAAAACAAGCTCAATATAAAATGCCCTTAAAGGAGTTTTTAAACATGGTTGAATCT
AAGATGCAAGAGGTTAGTTT

Downstream 100 bases:

>100_bases
TCGCGGCGCGTCTAAGCGTTTCAAAGTTAAAAAAAACTTGATTAAGCGTGGCAGCGCTTTTAAAAGCCATATTTTGACTA
AAAAAAGCCCTAAGCGTAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSRNEMLLNGDINFKEVRCVGDNGEVYGIISSKEALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKK
QKQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFKVVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGR
FVSWMFVPKAKEAPKNEKKTKENNPPFNRINLMKGENHAKNED

Sequences:

>Translated_203_residues
MSRNEMLLNGDINFKEVRCVGDNGEVYGIISSKEALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKK
QKQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFKVVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGR
FVSWMFVPKAKEAPKNEKKTKENNPPFNRINLMKGENHAKNED
>Mature_202_residues
SRNEMLLNGDINFKEVRCVGDNGEVYGIISSKEALNIAQNLGLDLVLISASAKPPVCKVMDYNKFRYQNEKKIKEAKKKQ
KQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFKVVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGRF
VSWMFVPKAKEAPKNEKKTKENNPPFNRINLMKGENHAKNED

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=42.7710843373494, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 23351; Mature: 23220

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNEMLLNGDINFKEVRCVGDNGEVYGIISSKEALNIAQNLGLDLVLISASAKPPVCKV
CCCCCEEEECCCCEEEEEEECCCCCEEEEECCHHHHHHHHHCCEEEEEEECCCCCCEEEE
MDYNKFRYQNEKKIKEAKKKQKQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFK
ECCCHHHCCCHHHHHHHHHHHHCCCHHHEEHHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGRFVSWMFVPKAKEAPKNEKKT
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHC
KENNPPFNRINLMKGENHAKNED
CCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SRNEMLLNGDINFKEVRCVGDNGEVYGIISSKEALNIAQNLGLDLVLISASAKPPVCKV
CCCCEEEECCCCEEEEEEECCCCCEEEEECCHHHHHHHHHCCEEEEEEECCCCCCEEEE
MDYNKFRYQNEKKIKEAKKKQKQIEIKEIKLSTQIAQNDINYKVKHAREFIESNKHVKFK
ECCCHHHCCCHHHHHHHHHHHHCCCHHHEEHHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
VVLKGRESQNSKAGLDVLFRVQTMMQDLANPEKEPKTEGRFVSWMFVPKAKEAPKNEKKT
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHC
KENNPPFNRINLMKGENHAKNED
CCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]