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The map label for this gene is rocA [H]

Identifier: 188526865

GI number: 188526865

Start: 51359

End: 54916

Strand: Reverse

Name: rocA [H]

Synonym: HPSH_00275

Alternate gene names: 188526865

Gene position: 54916-51359 (Counterclockwise)

Preceding gene: 188526868

Following gene: 188526864

Centisome position: 3.41

GC content: 40.67

Gene sequence:

>3558_bases
ATGCAAAAAATCATTGACGATTCGTTAGAATTAGCCAAAAAACTGCAAGATAGTATCAGTAACCATTTGAGCGAGCAAGA
AAAAGCGTTCCACTCTAAAATGCAAAAGCTTTTAAATAACCCTGAAAACAAGGTCATGCTCATAGAACTTATGGATCGGA
GTTTTAGATGCCTGGACAATAAAGCCCGCTTTGAAATGATTGAGCATGTTTTAGACAAATACAAAAGCCGTGAGATTTTT
TCTTCGTTTGAAAAATTGCTTTTAATGGGGTTTTTAAGCTTTGGGAAAATGCTCCCTGATATGAGCGTGCCTTTCTTTGT
CAATAAAATCAGAAGCGACACGAAAGCGATGGTCTTGGATCAAGAAGAAAGCCAATTAAAAGAGCGGATTTTAAAAAGAA
AAAATGAAAAAATCATTTTGAATGTGAATTTTATTGGCGAAGAGGTTTTAGGCGAAGAAGAAGCTAATGCGCGTTTTGAA
AAATACTCTCAAGCCCTAAAATCCAACTACATTCAATACATTTCCATTAAAATCACAACGATTTTTTCTCAAATCAATAT
CCTTGATTTTGAATACTCTAAAAAAGAGATTGTCAAACGCCTAGACGCTCTTTATGCCTTGGCTTTAGAAGAAGAAAAAA
AGCAAGGCATGCCTAAATTTATTAATTTGGATATGGAGGAATTTAGGGATTTAGAGCTCACGGTGGAGTCTTTTATGGAG
TCTATCGCTAAATTTGATTTGAACGCTGGTATTGTGTTGCAAGCCTATATCCCGGATTCTTATGAATATTTGAAAAAACT
GCACGCTTTTTCTAAAGAAAGGGTTTTAAAAGGGTTAAAGCCCATTAAAATCCGTTTTGTTAAGGGAGCGAACATGGAGA
GCGAAGAGACTATCGCTTCCGTGAAAGACTGGGCGTTACCCACATTTTCCAATAAGCAAGACACCGATTCTAATTACAAT
AAAATGCTGGATTTTGTTTTAGAGGGCGATAATTATAAATACATTCATATTGGCGCAGCGAGCCATAATATTTTTGAAAT
CGCTTATGTCTATACGCGCATCCATGCCCTTAATGACCCTGTTGTGTTAGAGCATTTTAGCTTTGAAATGCTAGAGGGCA
TGAGCTTGCAAGCGAGCCAGGAACTAAAAGAGATGCACAAACTCATTCTTTATGCGCCGGTGTGCGATGAAGCGCATTTT
AACAATGCGATCGCTTACTTGGTGAGAAGGTTAGATGAAAACACCTCAAGCGATAATTTCATGAAAGCTTTCTTTAACCT
CAAAGTAGGCACGAGCGAATGGAAAGATCAAGAACAACGCTTTTTAAATAGCCTTAAAGGAATCGCTACTTTAGACAATG
CCACCCACAGGACTCAAGATAGAAACGCCAAACAAAGCGGGCATACCACCTACCCAAACCACTCCTTTAAAAACGAAAGC
GATACCGATTTTATTTTAAAGGCCAACCGAGAATGGGCTAAAAAAGTGCGCGAAAAAATGCATAATGCCCCTATTTTAGA
GCTTTACCCAGAAATGGATGGGAGGTTTGAAGATCCTAATTTAACCCCTTTAGAAGTCTTTGATAAAATCCATCATAAAA
AAATCGCTAGCGTGCATTTAGCGGATAGGGAAGCGATTTTAAAAGCCCTAGAAGTGGCTAAAAGCGATAAGAGCCGTTTC
AGCCAAAAAAGCTTTACAGAAATCCATGCCTTAATGAGTCAAACCGCCCAGCTTTTTAGAGAAAGGCGAGGCGATTTGAT
AGGGATTTCGGCTTTAGAAGTGGGTAAGACTTTCGCTGAAACGGACGCTGAAGTGAGCGAAGCCATTGACTTTTTAGAGT
TTTACCCTTACAGCTTAAGGGTGCTACAAGAGCAAAATAAAAAAACGAAATTCACCCCCAAAGGCGTGGGTGTGGTCATT
GCCCCATGGAATTTCCCTGTGGGCATTTCTGTAGGCACTATCGCTGCCCCCCTAGCCGCTGGCAATCGGGTGATTTACAA
GCCCTCAAGTTTGTCTAGCGTAACGGGTTATAAGCTTTGCGAGTGTTTTTGGGATGCGGGCGTGCCTAGAGATGCGCTCA
TTTACTTGCCCTCTAAAGGGAGCGATATTAGCGAGCATCTTTTAAAAGATGAAAGCATCAAGTTTGCCATTTTAACAGGG
GGCGAAGACACCGCTTATAAAATGCTAGAAGCTAACCCCACTTTAGCCTTGAGCGCTGAAACAGGCGGTAAAAACGCCAC
TATTGTGAGCAAAATGGCAGACAGAGATCAGGCGATTAAGAATGTCATCCATTCAGCTTTTAGCAATTCGGGGCAAAAAT
GCTCCGCCACTTCGCTTTTAGTGTTGGAAAAAGAAGTCTATGAAGATGAGAACTTTAAAAAGACTCTAATAGATGCGACT
CTAAGCCTTAGCGTGGGCGATCCTTTTGATTTCAAAAACAAAATCGGCGCTCTAGCGGACAAGCCTAATGAAAAGGTCAT
CAAAGCCATAGACGAATTGAAAAGCTATGAAAATTACGAAATCCCGGTAAGCTTTGTCAATGATAACCCCTATTTGATGA
AGCCAAGCATCAAATACGGCACTAAAAAAGGCGATTTCACGCACCAAACTGAGCTTTTTACGCCCATTTTATCCGTGATG
AAGGCACAAGATTTAGACGAAGCGATAGACATAGTCAATTCTACCGGTTACGGGCTGACGAGCGCGTTAGAGTCTTTGGA
CGAAAGGGAGTGGGAATATTATTTAGAACGCATTGAAGCCGGTAATATCTATATCAACAAACCCACCACAGGAGCGATTG
TCTTACGCCAGCCTTTTGGGGGGGTTAAAAAATCCGCTGTGGGGTTTGGGAGAAAGGTGGGCATTTTTAACTATATCACG
CAATTTGTGAATATCCACCAAGAAGAAGAAGATGAAAACGCCCTAAAAAACCCCTTAAGCGAAGCTTTAGAAGGCTTGAC
TCAAAAAGGCTATGATGAACACACGCATGAGTTGAAGCGCGCGATTTTTATGGCAAAGAGCTACGCTTATCATTACAAGC
ATGAATTCAGCCAAGCTAAAGACTATGTCAAAATCAGAGGCGAAGACAACCTTTTTTCCTACACTAAAGTTAAAAGCGTG
GGCTATCGCATCACCGAAGAAGACACTTTAAGCGATATGTTAGGCGTTGCTTTGGCATGTTTAATTCCTCAAATCCCTTT
AACGCTCAGCATAGAAAACGAACGAGCGAACAAAGATTTATCATTTTTCTTAGAATGTTTAAAAGCGCTCCGAGCAAACG
CCCCTATTGTTTATGAAAGCTTGCAAAAATTTAGCGAGAAATTGAACGCTTTCAATCGTGTCCGTTATTTAAAAAGCGAT
TTGGATTTATTGCATGAACAAGCGAGCAGATTAGGGATTGTTTTAGCCACGGCTAAACCCTGCTTGAACGGGCGTTTTGA
ATTGCTGTATTACCACTTAGAGCGATCGGTTAGCATCTCTTATCATCGTTACGGGAATTTAGGCTCAAGGGTTTTAAGGC
GACCAACTTGCCACAAATCATGTTGTGCTGAAAAATAA

Upstream 100 bases:

>100_bases
AAAATTTAAAATTAAAAAACATTATCAACCCATGAGACTTAAAGCCGCCCGCTTAAAACATGCTACAATCAAGCCAAATT
CTTAAATAAAAGGTAAGCTC

Downstream 100 bases:

>100_bases
ATATTGTATTAAATAAGGAGATCAAAATGGGACATGTTGTTTTAAGCACCCCTATTGTTACGATGTTTGTCGCTTATTCG
CTGTTAATGCTCTATATTGG

Product: Proline/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 1185; Mature: 1185

Protein sequence:

>1185_residues
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIF
SSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFE
KYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASVKDWALPTFSNKQDTDSNYN
KMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHF
NNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHLADREAILKALEVAKSDKSRF
SQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVI
APWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTG
GEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDAT
LSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYEIPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVM
KAQDLDEAIDIVNSTGYGLTSALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
QFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVKSV
GYRITEEDTLSDMLGVALACLIPQIPLTLSIENERANKDLSFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSD
LDLLHEQASRLGIVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRRPTCHKSCCAEK

Sequences:

>Translated_1185_residues
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIF
SSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFE
KYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASVKDWALPTFSNKQDTDSNYN
KMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHF
NNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHLADREAILKALEVAKSDKSRF
SQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVI
APWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTG
GEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDAT
LSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYEIPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVM
KAQDLDEAIDIVNSTGYGLTSALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
QFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVKSV
GYRITEEDTLSDMLGVALACLIPQIPLTLSIENERANKDLSFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSD
LDLLHEQASRLGIVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRRPTCHKSCCAEK
>Mature_1185_residues
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIF
SSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFE
KYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASVKDWALPTFSNKQDTDSNYN
KMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHF
NNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHLADREAILKALEVAKSDKSRF
SQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVI
APWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTG
GEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDAT
LSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYEIPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVM
KAQDLDEAIDIVNSTGYGLTSALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
QFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVKSV
GYRITEEDTLSDMLGVALACLIPQIPLTLSIENERANKDLSFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSD
LDLLHEQASRLGIVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRRPTCHKSCCAEK

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=463, Percent_Identity=26.3498920086393, Blast_Score=154, Evalue=6e-37,
Organism=Homo sapiens, GI115387104, Length=467, Percent_Identity=24.1970021413276, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI238859541, Length=479, Percent_Identity=28.8100208768267, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI25777736, Length=479, Percent_Identity=28.8100208768267, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI25777734, Length=479, Percent_Identity=28.8100208768267, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI153266822, Length=442, Percent_Identity=27.6018099547511, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI238814322, Length=404, Percent_Identity=26.4851485148515, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI25777730, Length=442, Percent_Identity=25.7918552036199, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI21614513, Length=421, Percent_Identity=24.7030878859857, Blast_Score=127, Evalue=9e-29,
Organism=Homo sapiens, GI25777724, Length=453, Percent_Identity=25.60706401766, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI25777732, Length=443, Percent_Identity=24.8306997742664, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI21361176, Length=456, Percent_Identity=24.780701754386, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI25777728, Length=338, Percent_Identity=27.5147928994083, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI25952152, Length=454, Percent_Identity=23.7885462555066, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4507229, Length=420, Percent_Identity=26.9047619047619, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI25777726, Length=446, Percent_Identity=23.542600896861, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI25777721, Length=433, Percent_Identity=26.0969976905312, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI11095441, Length=509, Percent_Identity=23.3791748526523, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI301500698, Length=263, Percent_Identity=26.615969581749, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI188035924, Length=445, Percent_Identity=26.0674157303371, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128103, Length=445, Percent_Identity=26.0674157303371, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI310128093, Length=445, Percent_Identity=26.0674157303371, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI73695881, Length=339, Percent_Identity=25.3687315634218, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI73695879, Length=339, Percent_Identity=25.3687315634218, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI310128091, Length=384, Percent_Identity=26.8229166666667, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI206597441, Length=432, Percent_Identity=24.537037037037, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI206597439, Length=432, Percent_Identity=24.537037037037, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI22907049, Length=432, Percent_Identity=24.537037037037, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI4502043, Length=339, Percent_Identity=24.4837758112094, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI238814371, Length=339, Percent_Identity=24.4837758112094, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI71773324, Length=339, Percent_Identity=24.4837758112094, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=320, Percent_Identity=24.0625, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI4557303, Length=320, Percent_Identity=24.0625, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI310128089, Length=271, Percent_Identity=27.3062730627306, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1787250, Length=844, Percent_Identity=27.60663507109, Blast_Score=232, Evalue=1e-61,
Organism=Escherichia coli, GI1788042, Length=420, Percent_Identity=28.3333333333333, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI1786504, Length=463, Percent_Identity=26.133909287257, Blast_Score=146, Evalue=1e-35,
Organism=Escherichia coli, GI87081926, Length=418, Percent_Identity=24.6411483253589, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI87081896, Length=457, Percent_Identity=25.601750547046, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787715, Length=392, Percent_Identity=26.0204081632653, Blast_Score=124, Evalue=5e-29,
Organism=Escherichia coli, GI1789015, Length=480, Percent_Identity=25.4166666666667, Blast_Score=123, Evalue=6e-29,
Organism=Escherichia coli, GI1787558, Length=461, Percent_Identity=23.8611713665944, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI87082295, Length=467, Percent_Identity=24.8394004282655, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1787684, Length=465, Percent_Identity=23.2258064516129, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25143874, Length=456, Percent_Identity=28.9473684210526, Blast_Score=163, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=456, Percent_Identity=28.9473684210526, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17551164, Length=421, Percent_Identity=28.2660332541568, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562198, Length=449, Percent_Identity=25.6124721603563, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI133930964, Length=469, Percent_Identity=24.9466950959488, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144435, Length=471, Percent_Identity=23.3545647558386, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=489, Percent_Identity=24.9488752556237, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32564736, Length=399, Percent_Identity=24.5614035087719, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=27.9826464208243, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534176, Length=453, Percent_Identity=26.4900662251656, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115532534, Length=383, Percent_Identity=28.9817232375979, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71995606, Length=454, Percent_Identity=23.568281938326, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534119, Length=414, Percent_Identity=24.3961352657005, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564151, Length=426, Percent_Identity=26.9953051643192, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=344, Percent_Identity=26.453488372093, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71995613, Length=408, Percent_Identity=22.7941176470588, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146391, Length=334, Percent_Identity=24.8502994011976, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146394, Length=334, Percent_Identity=24.8502994011976, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566756, Length=334, Percent_Identity=24.8502994011976, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990744, Length=285, Percent_Identity=27.719298245614, Blast_Score=77, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323821, Length=486, Percent_Identity=26.7489711934156, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320917, Length=331, Percent_Identity=33.5347432024169, Blast_Score=147, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6325196, Length=459, Percent_Identity=27.8867102396514, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323822, Length=471, Percent_Identity=26.1146496815287, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6321826, Length=481, Percent_Identity=27.2349272349272, Blast_Score=138, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6324950, Length=473, Percent_Identity=25.369978858351, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319478, Length=470, Percent_Identity=25.1063829787234, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321828, Length=416, Percent_Identity=25.4807692307692, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323757, Length=336, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668425, Length=478, Percent_Identity=28.2426778242678, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24668417, Length=478, Percent_Identity=28.2426778242678, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24668413, Length=478, Percent_Identity=28.2426778242678, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24585660, Length=517, Percent_Identity=26.3056092843327, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI20129399, Length=463, Percent_Identity=25.0539956803456, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28571806, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571802, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571800, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571798, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571796, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571794, Length=487, Percent_Identity=24.435318275154, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281362580, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI62472918, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI62472926, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI62472936, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356737, Length=445, Percent_Identity=26.0674157303371, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=25.8928571428571, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24666674, Length=470, Percent_Identity=25.1063829787234, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24638876, Length=447, Percent_Identity=23.7136465324385, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24638878, Length=447, Percent_Identity=23.7136465324385, Blast_Score=88, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 135156; Mature: 135156

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCC
KARFEMIEHVLDKYKSREIFSSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEC
QEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFEKYSQALKSNYIQYISIKITT
CHHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEE
IFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIAS
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
VKDWALPTFSNKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDP
HHHHCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
VVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNF
EEEHHHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHH
MKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
HHHHHHEECCCHHHHHHHHHHHHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHL
CCCEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ADREAILKALEVAKSDKSRFSQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHH
TDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAA
CHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHC
GNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTG
CCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEEC
GEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLL
CCCHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
VLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYE
EEEHHHHCCCCHHHHHHHHHEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
IPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAQDLDEAIDIVNSTGYGLT
CEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
SALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHCCCCHHHHHHHHH
QFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DYVKIRGEDNLFSYTKVKSVGYRITEEDTLSDMLGVALACLIPQIPLTLSIENERANKDL
CEEEECCCCCCCHHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
SFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHEQASRLGIVLATAKP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
CLNGRFELLYYHLERSVSISYHRYGNLGSRVLRRPTCHKSCCAEK
CCCCCHHHEEEEHHCCEEEEHHHCCCHHHHHHCCCCCCHHHCCCC
>Mature Secondary Structure
MQKIIDDSLELAKKLQDSISNHLSEQEKAFHSKMQKLLNNPENKVMLIELMDRSFRCLDN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCC
KARFEMIEHVLDKYKSREIFSSFEKLLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEC
QEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFEKYSQALKSNYIQYISIKITT
CHHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEE
IFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFME
HHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
SIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIAS
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
VKDWALPTFSNKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDP
HHHHCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
VVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNF
EEEHHHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHH
MKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNATHRTQDRNAKQSGHTTYPNHSFKNES
HHHHHHEECCCHHHHHHHHHHHHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
DTDFILKANREWAKKVREKMHNAPILELYPEMDGRFEDPNLTPLEVFDKIHHKKIASVHL
CCCEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ADREAILKALEVAKSDKSRFSQKSFTEIHALMSQTAQLFRERRGDLIGISALEVGKTFAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHH
TDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAA
CHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHC
GNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTG
CCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEEC
GEDTAYKMLEANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLL
CCCHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
VLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYE
EEEHHHHCCCCHHHHHHHHHEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
IPVSFVNDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAQDLDEAIDIVNSTGYGLT
CEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHH
SALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYIT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHCCCCHHHHHHHHH
QFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DYVKIRGEDNLFSYTKVKSVGYRITEEDTLSDMLGVALACLIPQIPLTLSIENERANKDL
CEEEECCCCCCCHHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
SFFLECLKALRANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHEQASRLGIVLATAKP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
CLNGRFELLYYHLERSVSISYHRYGNLGSRVLRRPTCHKSCCAEK
CCCCCHHHEEEEHHCCEEEEHHHCCCHHHHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA