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The map label for this gene is ribH

Identifier: 188526814

GI number: 188526814

Start: 429

End: 899

Strand: Reverse

Name: ribH

Synonym: HPSH_00010

Alternate gene names: 188526814

Gene position: 899-429 (Counterclockwise)

Preceding gene: 188526815

Following gene: 188526813

Centisome position: 0.06

GC content: 45.44

Gene sequence:

>471_bases
ATGCAAATCATAGAAGGGAAATTGCACTTACAGGGGAATGAAAAAGTCGCTATTTTAACATCGCGCTTCAATCATATCAT
CACAGACAGATTGCAAGAAGGAGCGATTGACTGCTTTAAAAGGCATGGGGGCGATGAGAATCTTTTAGACATCGTGCTGG
TGCCTGGAGCTTATGAATTGCCTTTTATTTTAGAGAGGTTGTTAGGGAGCGAAAAATACGATGGCGTGTGCGTTTTAGGA
GCGATTATTAGAGGGGGGACTCCGCATTTTGACTATGTGAGCGCGGAAGCGACTAAGGGCATTGCCAACGCAATGCTAAA
ATACAGCATGCCTGTAAGCTTTGGCGTGCTGACCACGGACAATGTTGAGCAAGCGATTGAAAGAGCGGGCAGTAAAGCCG
GCAATAAGGGCTTTGAAGCGATGAGCACTCTCATTGAATTATTGAGCTTGTGCCAAACTCTCAAGGGTTAA

Upstream 100 bases:

>100_bases
AAACGCTCTAAGCGATGGGGCGAATATGCTAAAACCTGACGAGCTAGAACATTTAGTAGCCGACATGTTAAAAATCCAAA
ATTTATTTTAAAGGAATTTC

Downstream 100 bases:

>100_bases
AATGGCGACACGAACTCAAGCCAGGGGGGCGGTGGTTGAATTGTTGTATGCGTTTGAGAGCGGTAATGAAGAAATTAAAA
AAATCGCTTCCAGCATGTTA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MQIIEGKLHLQGNEKVAILTSRFNHIITDRLQEGAIDCFKRHGGDENLLDIVLVPGAYELPFILERLLGSEKYDGVCVLG
AIIRGGTPHFDYVSAEATKGIANAMLKYSMPVSFGVLTTDNVEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG

Sequences:

>Translated_156_residues
MQIIEGKLHLQGNEKVAILTSRFNHIITDRLQEGAIDCFKRHGGDENLLDIVLVPGAYELPFILERLLGSEKYDGVCVLG
AIIRGGTPHFDYVSAEATKGIANAMLKYSMPVSFGVLTTDNVEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
>Mature_156_residues
MQIIEGKLHLQGNEKVAILTSRFNHIITDRLQEGAIDCFKRHGGDENLLDIVLVPGAYELPFILERLLGSEKYDGVCVLG
AIIRGGTPHFDYVSAEATKGIANAMLKYSMPVSFGVLTTDNVEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=157, Percent_Identity=50.3184713375796, Blast_Score=151, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324429, Length=121, Percent_Identity=39.6694214876033, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16938; Mature: 16938

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIEGKLHLQGNEKVAILTSRFNHIITDRLQEGAIDCFKRHGGDENLLDIVLVPGAYEL
CCEECCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
PFILERLLGSEKYDGVCVLGAIIRGGTPHFDYVSAEATKGIANAMLKYSMPVSFGVLTTD
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
NVEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQIIEGKLHLQGNEKVAILTSRFNHIITDRLQEGAIDCFKRHGGDENLLDIVLVPGAYEL
CCEECCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
PFILERLLGSEKYDGVCVLGAIIRGGTPHFDYVSAEATKGIANAMLKYSMPVSFGVLTTD
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
NVEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA