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The map label for this gene is qseC [H]

Identifier: 187930689

GI number: 187930689

Start: 3792654

End: 3793973

Strand: Reverse

Name: qseC [H]

Synonym: Rpic_3625

Alternate gene names: 187930689

Gene position: 3793973-3792654 (Counterclockwise)

Preceding gene: 187930690

Following gene: 187930686

Centisome position: 96.23

GC content: 69.02

Gene sequence:

>1320_bases
ATGACAGCAGCCACATCTGCGGCTGCATCCGTGCAGCAGCGGCTATCGGTGTGGCTGTCGGTGATCATCGTGGCGGTGGC
GGTGCTGGCCGGCGGCTTTGCGTTTGCCTCGGCTTTTCGCGAAGCGCATGAATTGCAGGACGACGTCTTGCGCCAGGTCG
GGGCGATGTTCGACCCCGGCCACCTGCCCGCACCAGGCGAGGCGGCCGACGCGCCCAAGGTCTCGGACACGGAGGCGCGC
GTGATCGTGCAGGTGTTGCCGCCGGCCGGCGCGGTGCCTGCGGCCAGCCCGCCCGTGCTGACCGACGGCATGCAGACCGC
ACGCCTGGGCAAACGCGACTACCGCGTGTGGATCCGCACGCTCGCCAACGGCCAGCGCATCGCTGTGGCGCAGGAAACCG
CCGTGCGAGACGAAACCGCCCGCGACAGCGCTCTGCGCACGTTGATGCCGTTCCTGATACTTGTGCCGATCCTGCTGCTG
GCCGTCGCCCACGTGTTGCGCAAGATGTTCGCGCCCATCAAGCGGCTCGCGCATGAGGTGGACCAACGCGACGAGCGCCA
ACTGCACGCCATCGCCCCCGAAGCCGTGCCCGACGAGGTGCGCCCGTTCGTGGTGGCGATCAACCGCCTGCTCGCGCGCG
TGCAACAGTCCATGGACGCCCAGCACCGCTTTGTCGCCGATGCCGCGCACGAACTGCGCACGCCCCTTTCCGCACTGTCG
TTGCAGGCCGAGCGGCTCGGGCAGGCCGCGATGTCGCCCGACGCGCAGGCGCGGCTTGGCACGCTGCGCCAGGGCATCGA
GCGTAGCCGTGGGCTGCTCGAACAGCTCCTCACCCTGGCGCGCGCGCAAGAGGCCACCGGCGTGCCAACGGGCACCGTCT
CCGTCCAGAGCGTGTTCCGCAGCGTGCTGGAAGACCTCATGCCGCTTGCCGACGCCAAGCAGCTCGACATGGGCGTCACC
ACCGAAGCCGATGCGCGCGTGCATGCCAACGAGCTCGATCTCTTCGTCGTGGTGCGCAACCTCGTGGACAACGCCATCCG
CTACACACCGGAAGGCGGTCGCATCGACCTGTCGGTGGCCATTGACGCGGAGGTTGTGTCGATTGCCGTGCAGGACACCG
GCCCCGGCATCCCCATCGACGAACGCGCACGCGTGTTCGACCCGTTCTATCGCGTGCTCGGCAACGAGGCGACCGGCTCG
GGGCTCGGGTTGTCGATCGTGAGTACGGTGGTGCGGCGACTCGGCGGGGAGGTTGACCTCGGCGAGCCGGATGATCGTGC
CAGCGGGTTGCGGGTGACGGTGCGGTTGCCGACCGCCTAG

Upstream 100 bases:

>100_bases
GCAACGCGGTCGAATTCCTCATCCACGCACTGCGCAAAAAGCTCGGCGCGCAGGCCATCAAGAACGTCAGGGGAGTGGGA
TGGATGGTGCCGAGGGGCCA

Downstream 100 bases:

>100_bases
CGGCAACCGCACACCAATCTACCGCCGCACCCGGAATACCACCGCCAACCCCAGCAGAATCATCGCCATCCCCGCCACTG
CAACGGGCGCAAGGCGATGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTAATSAAASVQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPGHLPAPGEAADAPKVSDTEAR
VIVQVLPPAGAVPAASPPVLTDGMQTARLGKRDYRVWIRTLANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLL
AVAHVLRKMFAPIKRLAHEVDQRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALS
LQAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFRSVLEDLMPLADAKQLDMGVT
TEADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVAIDAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGS
GLGLSIVSTVVRRLGGEVDLGEPDDRASGLRVTVRLPTA

Sequences:

>Translated_439_residues
MTAATSAAASVQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPGHLPAPGEAADAPKVSDTEAR
VIVQVLPPAGAVPAASPPVLTDGMQTARLGKRDYRVWIRTLANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLL
AVAHVLRKMFAPIKRLAHEVDQRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALS
LQAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFRSVLEDLMPLADAKQLDMGVT
TEADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVAIDAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGS
GLGLSIVSTVVRRLGGEVDLGEPDDRASGLRVTVRLPTA
>Mature_438_residues
TAATSAAASVQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPGHLPAPGEAADAPKVSDTEARV
IVQVLPPAGAVPAASPPVLTDGMQTARLGKRDYRVWIRTLANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLLA
VAHVLRKMFAPIKRLAHEVDQRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALSL
QAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFRSVLEDLMPLADAKQLDMGVTT
EADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVAIDAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGSG
LGLSIVSTVVRRLGGEVDLGEPDDRASGLRVTVRLPTA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=310, Percent_Identity=35.1612903225806, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790551, Length=300, Percent_Identity=30.6666666666667, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=29.1512915129151, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=28.956228956229, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=302, Percent_Identity=32.4503311258278, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=28.0821917808219, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788279, Length=291, Percent_Identity=28.1786941580756, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=215, Percent_Identity=33.0232558139535, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=32.0512820512821, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788393, Length=291, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=26.9709543568465, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=277, Percent_Identity=25.6317689530686, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=27.3648648648649, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=27.1255060728745, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=24.7787610619469, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=28.2868525896414, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=24.8847926267281, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=214, Percent_Identity=23.3644859813084, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47107; Mature: 46975

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATSAAASVQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HLPAPGEAADAPKVSDTEARVIVQVLPPAGAVPAASPPVLTDGMQTARLGKRDYRVWIRT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHH
LANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLLAVAHVLRKMFAPIKRLAHEV
HCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LQAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVLEDLMPLADAKQLDMGVTTEADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVA
HHHHHHHHHCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEE
IDAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGSGLGLSIVSTVVRRLGGEVDL
ECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC
GEPDDRASGLRVTVRLPTA
CCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
TAATSAAASVQQRLSVWLSVIIVAVAVLAGGFAFASAFREAHELQDDVLRQVGAMFDPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HLPAPGEAADAPKVSDTEARVIVQVLPPAGAVPAASPPVLTDGMQTARLGKRDYRVWIRT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHH
LANGQRIAVAQETAVRDETARDSALRTLMPFLILVPILLLAVAHVLRKMFAPIKRLAHEV
HCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQRDERQLHAIAPEAVPDEVRPFVVAINRLLARVQQSMDAQHRFVADAAHELRTPLSALS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LQAERLGQAAMSPDAQARLGTLRQGIERSRGLLEQLLTLARAQEATGVPTGTVSVQSVFR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVLEDLMPLADAKQLDMGVTTEADARVHANELDLFVVVRNLVDNAIRYTPEGGRIDLSVA
HHHHHHHHHCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEE
IDAEVVSIAVQDTGPGIPIDERARVFDPFYRVLGNEATGSGLGLSIVSTVVRRLGGEVDL
ECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC
GEPDDRASGLRVTVRLPTA
CCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]