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The map label for this gene is qseB [H]

Identifier: 187930690

GI number: 187930690

Start: 3793970

End: 3794635

Strand: Reverse

Name: qseB [H]

Synonym: Rpic_3626

Alternate gene names: 187930690

Gene position: 3794635-3793970 (Counterclockwise)

Preceding gene: 187930691

Following gene: 187930689

Centisome position: 96.25

GC content: 66.97

Gene sequence:

>666_bases
ATGCGAGTCCTCCTAGTTGAAGACGACCCGATGATTGGCGCGGCCGTGGAAGCCGCGCTGCAGGACGCCGCCTACGCGGT
GGACTGGGTGCGTAACGGTCAGACCGCGTTGGATGTGGCCGCGCACCAACACTACGACCTGCTGCTGCTCGATCTCGGCC
TGCCCGGAAAGGACGGCCATGCAGTGCTCGGCAGCCTGCGCGCCCGCGACAATCCTGTCCCGGTGCTGATCCTGACCGCG
CGCGATGCGGTGGATGAGCGCGTACGCGGTCTCGACGGCGGCGCCGATGACTACATCCTCAAGCCCTTCGAGATGGTTGA
ACTGCTCGCCCGCATGCGCGCCGTCCTGCGCCGCAAGGGTGGGGCAGCGAGCCCCGTGCTCACCAATGGCGTGCTGACGC
TCGATCCCGCCGCGCACGAAGCGCGCATGGGCGATGCCGAGCCGGTACGCCTGTCCGCGCGCGAGTTTGCATTGCTGCAA
GCGCTCATGCTGCGGCCGGGCGCCATCCTTTCGCGCACGGAGCTGGAAGAGCGTATCTACGGCTGGGGCCACGAGGTAGC
GAGCAACGCGGTCGAATTCCTCATCCACGCACTGCGCAAAAAGCTCGGCGCGCAGGCCATCAAGAACGTCAGGGGAGTGG
GATGGATGGTGCCGAGGGGCCAATGA

Upstream 100 bases:

>100_bases
GACTGGTGCGGAATCTTCCTCCATCGCTCTGGAGAATCCGCCGAGTTGGCAGGCCCGGCGCGGTGCGCTGCAATCGGTCT
GACCGTTCACCCGACACTGA

Downstream 100 bases:

>100_bases
CAGCAGCCACATCTGCGGCTGCATCCGTGCAGCAGCGGCTATCGGTGTGGCTGTCGGTGATCATCGTGGCGGTGGCGGTG
CTGGCCGGCGGCTTTGCGTT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRVLLVEDDPMIGAAVEAALQDAAYAVDWVRNGQTALDVAAHQHYDLLLLDLGLPGKDGHAVLGSLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYILKPFEMVELLARMRAVLRRKGGAASPVLTNGVLTLDPAAHEARMGDAEPVRLSAREFALLQ
ALMLRPGAILSRTELEERIYGWGHEVASNAVEFLIHALRKKLGAQAIKNVRGVGWMVPRGQ

Sequences:

>Translated_221_residues
MRVLLVEDDPMIGAAVEAALQDAAYAVDWVRNGQTALDVAAHQHYDLLLLDLGLPGKDGHAVLGSLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYILKPFEMVELLARMRAVLRRKGGAASPVLTNGVLTLDPAAHEARMGDAEPVRLSAREFALLQ
ALMLRPGAILSRTELEERIYGWGHEVASNAVEFLIHALRKKLGAQAIKNVRGVGWMVPRGQ
>Mature_221_residues
MRVLLVEDDPMIGAAVEAALQDAAYAVDWVRNGQTALDVAAHQHYDLLLLDLGLPGKDGHAVLGSLRARDNPVPVLILTA
RDAVDERVRGLDGGADDYILKPFEMVELLARMRAVLRRKGGAASPVLTNGVLTLDPAAHEARMGDAEPVRLSAREFALLQ
ALMLRPGAILSRTELEERIYGWGHEVASNAVEFLIHALRKKLGAQAIKNVRGVGWMVPRGQ

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=45.6221198156682, Blast_Score=191, Evalue=2e-50,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=42.3963133640553, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=39.2694063926941, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=34.841628959276, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=33.9130434782609, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=35.3448275862069, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=35.8744394618834, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=36.3636363636364, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=36.1386138613861, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=30.9417040358744, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=34.061135371179, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.8701298701299, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=27.7533039647577, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=158, Percent_Identity=29.1139240506329, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=37.037037037037, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=31.4285714285714, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23987; Mature: 23987

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDDPMIGAAVEAALQDAAYAVDWVRNGQTALDVAAHQHYDLLLLDLGLPGKDGH
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCH
AVLGSLRARDNPVPVLILTARDAVDERVRGLDGGADDYILKPFEMVELLARMRAVLRRKG
HHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GAASPVLTNGVLTLDPAAHEARMGDAEPVRLSAREFALLQALMLRPGAILSRTELEERIY
CCCCCHHHCCEEEECCCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GWGHEVASNAVEFLIHALRKKLGAQAIKNVRGVGWMVPRGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MRVLLVEDDPMIGAAVEAALQDAAYAVDWVRNGQTALDVAAHQHYDLLLLDLGLPGKDGH
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCH
AVLGSLRARDNPVPVLILTARDAVDERVRGLDGGADDYILKPFEMVELLARMRAVLRRKG
HHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GAASPVLTNGVLTLDPAAHEARMGDAEPVRLSAREFALLQALMLRPGAILSRTELEERIY
CCCCCHHHCCEEEECCCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GWGHEVASNAVEFLIHALRKKLGAQAIKNVRGVGWMVPRGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]