| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
Click here to switch to the map view.
The map label for this gene is yvaG [H]
Identifier: 187930481
GI number: 187930481
Start: 3582086
End: 3582874
Strand: Reverse
Name: yvaG [H]
Synonym: Rpic_3415
Alternate gene names: 187930481
Gene position: 3582874-3582086 (Counterclockwise)
Preceding gene: 187930483
Following gene: 187930480
Centisome position: 90.88
GC content: 64.77
Gene sequence:
>789_bases ATGAACCTCCACCTTCAGAACAAGCTCGCTCTCGTGACCGGCTCGACCAAGGGCATCGGTCATGCCATTGCTGTAGCACT GGCCGCCGAAGGCGCCCGCGTGATCGTCAACGGCCGTACCCAAGCGTCCGTGGACGACGCGATTGCACGCCTGCGCACCG AAGTGCCCGACGCCCAGGTCGAGGGCTTTGCCGGTGACCTGTCCGATCCGGGCCAGGTCGACGCGCTGCTCGGCCGCTTT CCCAAGGTCGACATCCTCATCAACAACCTCGGTATCTTCGACCCCAAGCCGTTCGAGGAAATCGACGACGCCGAGTGGCA GCACTTCTTCAACGTGAACGTGCTGAGCGGCGCGCGGCTGTCGCGCGCCTACCTGCCTGGTATGCGTGCACAGAACTGGG GACGCATCGTGTTCATCAGCAGCGAGAGTGGCGTGCAGATTCCGGTGGAGATGATCCACTACGGTGTCACGAAGACCGCG CTGCTGGGCCTCTCGCGCGGATTGGCCGAGTTGACCGCGGGCACGGCCATCACGGTGAATGCCGTGCTGCCGGGGCCGAC GCGTTCCGAAGGCGTAGACGCGTTTGTCGAAAAGCTCTCGGGCGGGCAGAGCTTCGAAGCGTTCGAGAAAACCTTCTTCG AGACGGCGCGGCCGACCTCGCTCATCAAGCGCTTTGCCACCACGCAGGAAGTCGCCAACCTGGTTGCCTACGTGGCCAGC CCGCTGTCGTCGGCCACCACGGGCGCTGCGCTGCGTGTGGACGGCGGCGTGGTGAAGTCGGCGTTCTAG
Upstream 100 bases:
>100_bases CGAGGCGGTTCGTATCATGGTTGAAACGTCGACGCCGTGACCAACTTGCACCATGTGGCGCGGCGTGCTCGTCCTCCTCC ATTTTCCTTTTTTGAATGCC
Downstream 100 bases:
>100_bases AACGTCAGCCCTGACGAACGCACCATTCCGGCGCGCGGCCCCGGCTTTTACGCTGGCCGTGTCGCTGGTGCATGCCGGCG GGACCCGCCGGCAGTGCGTC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 262; Mature: 262
Protein sequence:
>262_residues MNLHLQNKLALVTGSTKGIGHAIAVALAAEGARVIVNGRTQASVDDAIARLRTEVPDAQVEGFAGDLSDPGQVDALLGRF PKVDILINNLGIFDPKPFEEIDDAEWQHFFNVNVLSGARLSRAYLPGMRAQNWGRIVFISSESGVQIPVEMIHYGVTKTA LLGLSRGLAELTAGTAITVNAVLPGPTRSEGVDAFVEKLSGGQSFEAFEKTFFETARPTSLIKRFATTQEVANLVAYVAS PLSSATTGAALRVDGGVVKSAF
Sequences:
>Translated_262_residues MNLHLQNKLALVTGSTKGIGHAIAVALAAEGARVIVNGRTQASVDDAIARLRTEVPDAQVEGFAGDLSDPGQVDALLGRF PKVDILINNLGIFDPKPFEEIDDAEWQHFFNVNVLSGARLSRAYLPGMRAQNWGRIVFISSESGVQIPVEMIHYGVTKTA LLGLSRGLAELTAGTAITVNAVLPGPTRSEGVDAFVEKLSGGQSFEAFEKTFFETARPTSLIKRFATTQEVANLVAYVAS PLSSATTGAALRVDGGVVKSAF >Mature_262_residues MNLHLQNKLALVTGSTKGIGHAIAVALAAEGARVIVNGRTQASVDDAIARLRTEVPDAQVEGFAGDLSDPGQVDALLGRF PKVDILINNLGIFDPKPFEEIDDAEWQHFFNVNVLSGARLSRAYLPGMRAQNWGRIVFISSESGVQIPVEMIHYGVTKTA LLGLSRGLAELTAGTAITVNAVLPGPTRSEGVDAFVEKLSGGQSFEAFEKTFFETARPTSLIKRFATTQEVANLVAYVAS PLSSATTGAALRVDGGVVKSAF
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=33.7254901960784, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=31.9230769230769, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=37.8947368421053, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.6409266409266, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=28.740157480315, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI7705925, Length=262, Percent_Identity=31.6793893129771, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=31.1538461538462, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=30.0518134715026, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI109715829, Length=190, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI126723191, Length=204, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=29.0566037735849, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7705855, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI31542939, Length=214, Percent_Identity=27.1028037383178, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI226371731, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI10190746, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI7657478, Length=221, Percent_Identity=30.316742081448, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI223718074, Length=220, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=263, Percent_Identity=31.9391634980989, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=32.183908045977, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=29.0697674418605, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787905, Length=264, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=32.183908045977, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=28.8461538461538, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI87082160, Length=274, Percent_Identity=27.7372262773723, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1789378, Length=272, Percent_Identity=30.5147058823529, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=25.8687258687259, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.7937743190661, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=26.9961977186312, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=35.0194552529183, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=35.5212355212355, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=31.8897637795276, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.9803921568627, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=31.6793893129771, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=31.6602316602317, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=30.9160305343511, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.1526717557252, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI25147288, Length=272, Percent_Identity=29.0441176470588, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=30.1526717557252, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI115534694, Length=266, Percent_Identity=29.6992481203008, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17565030, Length=195, Percent_Identity=32.8205128205128, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=27.9245283018868, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=31.7460317460317, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.4367816091954, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=27.8388278388278, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559552, Length=191, Percent_Identity=30.3664921465969, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=213, Percent_Identity=30.0469483568075, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.6458333333333, Blast_Score=85, Evalue=9e-18, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=33.4615384615385, Blast_Score=117, Evalue=9e-27, Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.1158301158301, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.5882352941176, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=28.515625, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=27.2251308900524, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=28.7937743190661, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644337, Length=200, Percent_Identity=30, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=30.2857142857143, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=165, Percent_Identity=31.5151515151515, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27766; Mature: 27766
Theoretical pI: Translated: 5.70; Mature: 5.70
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLHLQNKLALVTGSTKGIGHAIAVALAAEGARVIVNGRTQASVDDAIARLRTEVPDAQV CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHH EGFAGDLSDPGQVDALLGRFPKVDILINNLGIFDPKPFEEIDDAEWQHFFNVNVLSGARL CCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHEEEEEEECCCHH SRAYLPGMRAQNWGRIVFISSESGVQIPVEMIHYGVTKTALLGLSRGLAELTAGTAITVN HHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEE AVLPGPTRSEGVDAFVEKLSGGQSFEAFEKTFFETARPTSLIKRFATTQEVANLVAYVAS EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH PLSSATTGAALRVDGGVVKSAF HHCCCCCCCEEEECCCCCCCCC >Mature Secondary Structure MNLHLQNKLALVTGSTKGIGHAIAVALAAEGARVIVNGRTQASVDDAIARLRTEVPDAQV CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHH EGFAGDLSDPGQVDALLGRFPKVDILINNLGIFDPKPFEEIDDAEWQHFFNVNVLSGARL CCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHEEEEEEECCCHH SRAYLPGMRAQNWGRIVFISSESGVQIPVEMIHYGVTKTALLGLSRGLAELTAGTAITVN HHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEE AVLPGPTRSEGVDAFVEKLSGGQSFEAFEKTFFETARPTSLIKRFATTQEVANLVAYVAS EEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH PLSSATTGAALRVDGGVVKSAF HHCCCCCCCEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]