Click here to switch to the map view.

The map label for this gene is glk [H]

Identifier: 187930412

GI number: 187930412

Start: 3502718

End: 3503581

Strand: Reverse

Name: glk [H]

Synonym: Rpic_3346

Alternate gene names: 187930412

Gene position: 3503581-3502718 (Counterclockwise)

Preceding gene: 187930414

Following gene: 187930409

Centisome position: 88.87

GC content: 69.1

Gene sequence:

>864_bases
ATGCCTTCGTTCTCCGTTCCCCTGCTCAACGCCTTGCGCGCCCAGCTGCCCGCGCTTTCGCCGGCGCAGCAGGGCGTGGC
GCGGTTGATCCTGGACGCGCCGGAGCTGTCGCTCGAACAATCGGTGGAGACGCTGGCCGTGCGCGCCGGCGTGTCGATGC
CGACCATCGTGCGGATGTGCCAGGCGCTCGGATTTGAAGGCTTGCGCGAGTTCAAGGCCACGCTGGCCGCCGAGCTGGCG
CACGCGCAGCCGACGCTGCCGGGCCATGTCGGCCGGGCGGACCCGCCTGCGCTGGTCGCCAGCAAGGTCATTGACGGCGC
TACGCGGGCGCTGGCCAAGCTGCGTGAATCGCTGTCCACCACGCAGGTCGACGCCGCCGCCGAGCGCATTGCCCGCGCGC
GCCGCGTCGATTGCTATGCGGCCGGTGCGGCCTCATCGTTCATGGCGAACGACATGCAGGCGCGGCTCATGCGGTTAGGG
CTGGCGTCCAACGCCTACTTCGATGCGCATCTGCAGCTCGTGTCAGCCGCCATGCTCGGCGCGTCCGACGTCGTGGTGGC
GTTCTCGCACGTGGGGCGCATGCCGTATCTGCTGGAGTCGATCGCGTATGCGGCCGAGCAGGGTGCGTGCGTGATCGCCA
TCACTCAAGCGGGCACGCCACTGGCCGAGCGCGCGCAGATCGCGCTGACGGTGGACGTGCCGGAAGATGCGGTGATGCGG
GTCGGCACCGAGGCGTACCTCGTGCATCTGACCGTTATCGAAATCCTGATGACCTGCGTGGCGCAGCGCCGCGACGAGAT
GGTGCGTTCGCGCATGCGGGCAATCCAGCGGCTGCTGACCGAGCGCAGCGTCGATCGCCCGTAA

Upstream 100 bases:

>100_bases
CTTACAGATTCTTGGGGGTTTTCCCTCGGGCAGGCGGCGTGGGGCGGGGCTGCCGCTACACTGGCGACGCTCATTTCTGT
TCGCCGCCCACGTATCGCCC

Downstream 100 bases:

>100_bases
TCGACCGCGACGACGCGTCGAAGGGGAAAAAAATGGCGCCACGCGGGCGCCATCCACAACACATGCGGCACTCAAAGCCG
CGAGATCGCCAGCCCGATCG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPSFSVPLLNALRAQLPALSPAQQGVARLILDAPELSLEQSVETLAVRAGVSMPTIVRMCQALGFEGLREFKATLAAELA
HAQPTLPGHVGRADPPALVASKVIDGATRALAKLRESLSTTQVDAAAERIARARRVDCYAAGAASSFMANDMQARLMRLG
LASNAYFDAHLQLVSAAMLGASDVVVAFSHVGRMPYLLESIAYAAEQGACVIAITQAGTPLAERAQIALTVDVPEDAVMR
VGTEAYLVHLTVIEILMTCVAQRRDEMVRSRMRAIQRLLTERSVDRP

Sequences:

>Translated_287_residues
MPSFSVPLLNALRAQLPALSPAQQGVARLILDAPELSLEQSVETLAVRAGVSMPTIVRMCQALGFEGLREFKATLAAELA
HAQPTLPGHVGRADPPALVASKVIDGATRALAKLRESLSTTQVDAAAERIARARRVDCYAAGAASSFMANDMQARLMRLG
LASNAYFDAHLQLVSAAMLGASDVVVAFSHVGRMPYLLESIAYAAEQGACVIAITQAGTPLAERAQIALTVDVPEDAVMR
VGTEAYLVHLTVIEILMTCVAQRRDEMVRSRMRAIQRLLTERSVDRP
>Mature_286_residues
PSFSVPLLNALRAQLPALSPAQQGVARLILDAPELSLEQSVETLAVRAGVSMPTIVRMCQALGFEGLREFKATLAAELAH
AQPTLPGHVGRADPPALVASKVIDGATRALAKLRESLSTTQVDAAAERIARARRVDCYAAGAASSFMANDMQARLMRLGL
ASNAYFDAHLQLVSAAMLGASDVVVAFSHVGRMPYLLESIAYAAEQGACVIAITQAGTPLAERAQIALTVDVPEDAVMRV
GTEAYLVHLTVIEILMTCVAQRRDEMVRSRMRAIQRLLTERSVDRP

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=279, Percent_Identity=31.8996415770609, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082369, Length=263, Percent_Identity=26.2357414448669, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082130, Length=272, Percent_Identity=26.4705882352941, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 30698; Mature: 30567

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSFSVPLLNALRAQLPALSPAQQGVARLILDAPELSLEQSVETLAVRAGVSMPTIVRMC
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
QALGFEGLREFKATLAAELAHAQPTLPGHVGRADPPALVASKVIDGATRALAKLRESLST
HHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TQVDAAAERIARARRVDCYAAGAASSFMANDMQARLMRLGLASNAYFDAHLQLVSAAMLG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
ASDVVVAFSHVGRMPYLLESIAYAAEQGACVIAITQAGTPLAERAQIALTVDVPEDAVMR
CHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCEEEEEEECCHHHHHH
VGTEAYLVHLTVIEILMTCVAQRRDEMVRSRMRAIQRLLTERSVDRP
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PSFSVPLLNALRAQLPALSPAQQGVARLILDAPELSLEQSVETLAVRAGVSMPTIVRMC
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
QALGFEGLREFKATLAAELAHAQPTLPGHVGRADPPALVASKVIDGATRALAKLRESLST
HHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TQVDAAAERIARARRVDCYAAGAASSFMANDMQARLMRLGLASNAYFDAHLQLVSAAMLG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
ASDVVVAFSHVGRMPYLLESIAYAAEQGACVIAITQAGTPLAERAQIALTVDVPEDAVMR
CHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCEEEEEEECCHHHHHH
VGTEAYLVHLTVIEILMTCVAQRRDEMVRSRMRAIQRLLTERSVDRP
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA