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The map label for this gene is mraY

Identifier: 187930160

GI number: 187930160

Start: 3229559

End: 3230728

Strand: Reverse

Name: mraY

Synonym: Rpic_3092

Alternate gene names: 187930160

Gene position: 3230728-3229559 (Counterclockwise)

Preceding gene: 187930161

Following gene: 187930159

Centisome position: 81.94

GC content: 62.65

Gene sequence:

>1170_bases
ATGTTATTGGCATTGGCGCAATGGTTGCAGAACGACTACGGCTTCCTGCGCGTCTTCAACTATCTGACGTTCCGCGCCGT
GATGGCATCGCTCACGGCGCTGGTGATCGGCCTCGGGTTCGGGCCGTTCGTGATCCGTCGCCTGACGGAACTGAAAGTCG
GCCAGGCTGTGCGCAGCTATGGCCCGCAGACGCACCTGGTCAAGGCCGGCACGCCCACCATGGGCGGTGTGCTGGTGCTC
ATCGGCATTGCCGTGTCGACGCTGCTGTGGGCGGACTGGGGCAACCGCTTCATCTGGATCGTGCTGCTGGTCACGCTCGG
CTATGGCGCGATCGGCTGGGTCGATGACTACCGCAAGGTCGTGCACCGCGATCCAAAGGGGATGTCTTCGCGCGAGAAGT
TCTTCTGGCAGACCGTGATCGGCCTGTTTGCGGCGGCGTATCTGGCGTTCTCGGTGTCCGAGACCAGCAACATGCGCGTG
CTCGAGCTGTTCATGGAGTGGGTGCGCAGCGGCCTGTCGCTGAACCTGCCGGCCAAGTCGCACCTGATCGTGCCGTTCTT
CAAGGAGATCAGCTACCCGCTCGGCGTGTTCGGTTTCATCATCCTGACGTACCTCGTGATCGTCGGCTCCAGCAATGCGG
TGAACCTGACCGACGGCCTTGATGGCCTCGTCATCATGCCGGTCGTGCTCGTGGGCAGCGCGCTGGGCGTGTTCGCGTAC
GTGATGGGTAGCGCTGTCTACAGCAAATACCTGCTGTTCCCACACATTCCGGGCGCAGGCGAGCTGCTGATTTTCTGCTC
GGCGATGGCGGGTGCGGGGCTTGCCTTCCTGTGGTTCAACGCGCATCCGGCACAGGTGTTCATGGGTGACGTCGGCGCGC
TGGCGCTGGGCGGCGCGCTTGGCACCATCGCCGTGATCGTGCGCCAGGAAATCGTGCTCTTCATCATGGGCGGCATCTTC
GTGGCGGAGACCGTCTCGGTGATGCTGCAGGTGACGTGGTTCAAGTTCACCAAGAAACGTTATGGCGAGGGCCGGCGCCT
GTTCCGCATGGCGCCGCTGCATCATCATTTCGAGCTGTCCGGCTGGAAGGAAACGCAAGTGGTCGTGCGCTTCTGGGTCA
TCACCATGATGCTGGTGCTGATCGGCCTGTCGACCCTGAAGCTGCGGTGA

Upstream 100 bases:

>100_bases
GATGGAACGCATTGTGGAAGCGCTGGTCTTGAAAGACCCGGTAGCGGATTCGCCAGCCGGTTCCAACACACAACAGCAGC
ATTAAGGGAAGCAAGAACCC

Downstream 100 bases:

>100_bases
GCACGGACATGACCGACATGACCGACGACTCCATCACCCCGGACGACGATATGGCCGCCACGCAGCCCGACGCCGCCGTG
GACGCCGTTGTCGCGACACT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQNDYGFLRVFNYLTFRAVMASLTALVIGLGFGPFVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWADWGNRFIWIVLLVTLGYGAIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFMEWVRSGLSLNLPAKSHLIVPFFKEISYPLGVFGFIILTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKKRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWVITMMLVLIGLSTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQNDYGFLRVFNYLTFRAVMASLTALVIGLGFGPFVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWADWGNRFIWIVLLVTLGYGAIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFMEWVRSGLSLNLPAKSHLIVPFFKEISYPLGVFGFIILTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKKRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWVITMMLVLIGLSTLKLR
>Mature_389_residues
MLLALAQWLQNDYGFLRVFNYLTFRAVMASLTALVIGLGFGPFVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWADWGNRFIWIVLLVTLGYGAIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFMEWVRSGLSLNLPAKSHLIVPFFKEISYPLGVFGFIILTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIF
VAETVSVMLQVTWFKFTKKRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWVITMMLVLIGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=52.9562982005141, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_RALPJ (B2UCY0)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900647.1
- GeneID:   6286067
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_3092
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 42974; Mature: 42974

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18512aac)-; HASH(0x1853c1cc)-; HASH(0x18d50c08)-; HASH(0x18d427cc)-; HASH(0x157d9398)-; HASH(0x187cc494)-; HASH(0x1616e1b4)-; HASH(0x18d530ec)-; HASH(0x1895139c)-; HASH(0x18d4bab0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA