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The map label for this gene is ftsW [H]

Identifier: 187930158

GI number: 187930158

Start: 3226672

End: 3227913

Strand: Reverse

Name: ftsW [H]

Synonym: Rpic_3090

Alternate gene names: 187930158

Gene position: 3227913-3226672 (Counterclockwise)

Preceding gene: 187930159

Following gene: 187930157

Centisome position: 81.87

GC content: 63.45

Gene sequence:

>1242_bases
ATGAGCGACACCCAGATCAAGCGCAGCGGCTTCATCGGCGCGACCATCGGCAATGCGTGGGATGGCCTGCGCGACGCCGT
TTCAGGGGTCAAGCCCACGCGCTCCAAGATGATGGAGTACGACCAGCCGCTGTTGTGGGTGGCGATCGTGCTGCTCGGCC
TCGGGCTGGTGATGGTGTATTCGGCGTCGATCGCGTTGCCGGATTCGCCCAAGTACGCCAACTACAGCAACGGGCATTTC
CTGATCCGCCACATCTTCTCGCTGGTCATCGGGCTGATCGGTGCGATCGTCGCATTCCAGATTCCGGTCAAGTTCTGGGA
CAAATACGCTCCGAAGCTCTTCATCATTGCACTGGTCCTGCTGGTGATTGTGCTCGTGCCGCACCTCGGCAAGGGCGTGA
ATGGCGCGCGCCGCTGGCTGCCGCTGGGCGTCATGAATTTCCAGCCGTCCGAGCTGATGAAGCTGGCGGTGGTGCTGTAC
GCCGCCAACTACACCGTGCGCAAGCAGGACTGGATGCAGAGCGTGCGCAAGGGGTTCCTGCCCATGGGCGTGGCCGTGGC
GTTTGTCGGCTCGCTCCTGCTGTTGGAGCCGGACATGGGCGCGTTCCTGGTGATCGCAGCCGTGGCCATGGGCATCCTGT
TCCTGGGCGGCGTGAACGGCAAGCTGTTCGGCGGCCTCGTGCTCACCGCGGTTTCCACCTTCTCGCTGCTGATCGTGGCG
TCGCCCTGGCGACGCGAGCGGATCTTCGCCTACCTGAACCCCTGGCAAGAGGAATACGCGCAGGGCAAGGCATACCAGCT
CACGCACTCGCTGATCGCTTTCGGCCGTGGCGAGTGGACCGGCGTTGGCCTGGGCGGGAGCATCGAGAAGCTGCACTACC
TGCCTGAAGCGCATACCGACTTCATTCTCGCCGTCATTGGCGAGGAACTGGGCTTTGTCGGCGTGCTGATCGTGATCCTG
CTGTTCTACTGGATGGTGCGCCGCGCCTTCGAGATCGGCCGCACCGCGCTGCAGCTCGACCGTACGTTCGCAGGCCTCGT
TGCCAAGGGACTGGGAATCTGGATCGGCTGGCAGGCCTTCATCAACATGGGCGTGAACCTGGGCCTGCTGCCGACCAAGG
GTCTGACGCTGCCGCTGGTCAGCTACGGCGGCTCCGGCATCCTGATGAACTGCGTCGCGATCGCGGTGCTGCTGCGTATC
GACTATGAAAACCGCGTGCTGATGCGTGGGGGCAAGGTATGA

Upstream 100 bases:

>100_bases
CGGCGTGCGCAAGCTTCGACATGTTCCGCAACTACGAACACCGCGCCCAGGTGTTCCACGAGGCCGTGGTCGCATTGGCG
GCAGACCGAGGAGTCCTCCT

Downstream 100 bases:

>100_bases
CGGCAGGCAATTCGGCCCGTCTGGCGCCGCGCACGCTCCTCGTCATGGCCGGCGGCACGGGCGGTCACATCTTCCCCGCG
CTGTCGGTGGCCAAGCTGTT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSDTQIKRSGFIGATIGNAWDGLRDAVSGVKPTRSKMMEYDQPLLWVAIVLLGLGLVMVYSASIALPDSPKYANYSNGHF
LIRHIFSLVIGLIGAIVAFQIPVKFWDKYAPKLFIIALVLLVIVLVPHLGKGVNGARRWLPLGVMNFQPSELMKLAVVLY
AANYTVRKQDWMQSVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLIVA
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVIL
LFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVAIAVLLRI
DYENRVLMRGGKV

Sequences:

>Translated_413_residues
MSDTQIKRSGFIGATIGNAWDGLRDAVSGVKPTRSKMMEYDQPLLWVAIVLLGLGLVMVYSASIALPDSPKYANYSNGHF
LIRHIFSLVIGLIGAIVAFQIPVKFWDKYAPKLFIIALVLLVIVLVPHLGKGVNGARRWLPLGVMNFQPSELMKLAVVLY
AANYTVRKQDWMQSVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLIVA
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVIL
LFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVAIAVLLRI
DYENRVLMRGGKV
>Mature_412_residues
SDTQIKRSGFIGATIGNAWDGLRDAVSGVKPTRSKMMEYDQPLLWVAIVLLGLGLVMVYSASIALPDSPKYANYSNGHFL
IRHIFSLVIGLIGAIVAFQIPVKFWDKYAPKLFIIALVLLVIVLVPHLGKGVNGARRWLPLGVMNFQPSELMKLAVVLYA
ANYTVRKQDWMQSVRKGFLPMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLIVAS
PWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEELGFVGVLIVILL
FYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVAIAVLLRID
YENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=384, Percent_Identity=45.3125, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1786853, Length=331, Percent_Identity=34.441087613293, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45200; Mature: 45068

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
SDTQIKRSGFIGATIGNAWDGLRDAVSGVKPTRSKMMEYDQPLLWVAIVLLGLGLVMVY
CCCCCHHCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SASIALPDSPKYANYSNGHFLIRHIFSLVIGLIGAIVAFQIPVKFWDKYAPKLFIIALVL
HCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHH
LVIVLVPHLGKGVNGARRWLPLGVMNFQPSELMKLAVVLYAANYTVRKQDWMQSVRKGFL
HHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PMGVAVAFVGSLLLLEPDMGAFLVIAAVAMGILFLGGVNGKLFGGLVLTAVSTFSLLIVA
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEE
SPWRRERIFAYLNPWQEEYAQGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
CCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
FILAVIGEELGFVGVLIVILLFYWMVRRAFEIGRTALQLDRTFAGLVAKGLGIWIGWQAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INMGVNLGLLPTKGLTLPLVSYGGSGILMNCVAIAVLLRIDYENRVLMRGGKV
HHCCCCEEEECCCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]