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The map label for this gene is dapB

Identifier: 187930052

GI number: 187930052

Start: 3110763

End: 3111554

Strand: Reverse

Name: dapB

Synonym: Rpic_2984

Alternate gene names: 187930052

Gene position: 3111554-3110763 (Counterclockwise)

Preceding gene: 187930053

Following gene: 187930051

Centisome position: 78.92

GC content: 64.77

Gene sequence:

>792_bases
ATGAAAATTGCGATTGCAGGCGCCTCGGGCCGCATGGGCCAGATGCTGATCGACACCGTACTGCGCACGCCCGGCGTGAC
GCTGGGCGCTGCGCTGGACCGCCCAGGCAGCGACGCCGTGGGCCAGGACGCCGGCGTCAAGCTGGGCAAGACCACCGGCG
TGATTGTGACCGACGACGTGCGTGCGGGGCTTTCGCAAGCCGACGTGCTGATCGACTTCACGCGTCCTGATGCAACGCTC
AATCACCTGAACGTGGCCCGTGAGCTGGGCACCGCGGTGGTCATCGGTACAACCGGCTTCACGGCCGAGCAGAAGGCCAG
CTTCAAGACCTACGGCGAGTCGATCGGCGTGGTCTGGGCACCGAACATGAGCGTGGGCGTGAACGCGACGTTCAAGCTGA
TCGAAGTCGCCGCCAAGATCCTGGCGCAGGGCTACGACGTCGAAATCATCGAGGCGCATCACAAGCACAAGATCGACGCG
CCGTCGGGCACCGCGCTCAAGATGGGCGAGATCGTGGCCGAGGCGCAGGGCACCAAGCTGGCTGATCGCGCAGTGTACGC
CCGAGAAGGGGAGACCGGCCCGCGGGAGCTTGGCACCATCGGTTTTGCCACCGTGCGTGGCGGTGACATCGTGGGCGACC
ACACCGTGCTGTTTGCTGGCGACGGCGAGCGCATCGAAATCACGCATCGCTCCAACACCCGCCAGTCGTATGCCGAAGGT
GCAGTGCGTGCTGCGGTTTACGTGGCTGGCAAGAAAGGCTTGTACGACATGAACGACGTGCTCGGCCTGTAA

Upstream 100 bases:

>100_bases
AGGCATCGGCACACCATCTTCGAGCGAGCGGCGGACGGGTTCCGCCGCTTGTGCGTTTGACAGACCGTTTTCTCTTTTGC
AGCTTTTCGCTTCCACCGAC

Downstream 100 bases:

>100_bases
ATCAGGCGGGCAGGAAAGGGCGCCGGCAGGCCTGTCCGGCGCCCTTTTTTTCTCCGCTCGCGATCGCCCGGATGGCGCGG
GTGGCGACGGTATAATCGGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLGAALDRPGSDAVGQDAGVKLGKTTGVIVTDDVRAGLSQADVLIDFTRPDATL
NHLNVARELGTAVVIGTTGFTAEQKASFKTYGESIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIIEAHHKHKIDA
PSGTALKMGEIVAEAQGTKLADRAVYAREGETGPRELGTIGFATVRGGDIVGDHTVLFAGDGERIEITHRSNTRQSYAEG
AVRAAVYVAGKKGLYDMNDVLGL

Sequences:

>Translated_263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLGAALDRPGSDAVGQDAGVKLGKTTGVIVTDDVRAGLSQADVLIDFTRPDATL
NHLNVARELGTAVVIGTTGFTAEQKASFKTYGESIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIIEAHHKHKIDA
PSGTALKMGEIVAEAQGTKLADRAVYAREGETGPRELGTIGFATVRGGDIVGDHTVLFAGDGERIEITHRSNTRQSYAEG
AVRAAVYVAGKKGLYDMNDVLGL
>Mature_263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLGAALDRPGSDAVGQDAGVKLGKTTGVIVTDDVRAGLSQADVLIDFTRPDATL
NHLNVARELGTAVVIGTTGFTAEQKASFKTYGESIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIIEAHHKHKIDA
PSGTALKMGEIVAEAQGTKLADRAVYAREGETGPRELGTIGFATVRGGDIVGDHTVLFAGDGERIEITHRSNTRQSYAEG
AVRAAVYVAGKKGLYDMNDVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=55.0943396226415, Blast_Score=270, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_RALPJ (B2UCA2)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900539.1
- ProteinModelPortal:   B2UCA2
- SMR:   B2UCA2
- GeneID:   6289077
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2984
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27474; Mature: 27474

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGASGRMGQMLIDTVLRTPGVTLGAALDRPGSDAVGQDAGVKLGKTTGVIVTDDV
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHCCCCCCCCCCCCCCCEEECCCCCEEEECHH
RAGLSQADVLIDFTRPDATLNHLNVARELGTAVVIGTTGFTAEQKASFKTYGESIGVVWA
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHCHHHHHCCCCCEEEC
PNMSVGVNATFKLIEVAAKILAQGYDVEIIEAHHKHKIDAPSGTALKMGEIVAEAQGTKL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCCH
ADRAVYAREGETGPRELGTIGFATVRGGDIVGDHTVLFAGDGERIEITHRSNTRQSYAEG
HHHEEEECCCCCCCHHHCCEEEEEECCCCEECCCEEEEECCCCEEEEEECCCCHHHHHHH
AVRAAVYVAGKKGLYDMNDVLGL
HEEEEEEEECCCCCCCHHHHHCC
>Mature Secondary Structure
MKIAIAGASGRMGQMLIDTVLRTPGVTLGAALDRPGSDAVGQDAGVKLGKTTGVIVTDDV
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHCCCCCCCCCCCCCCCEEECCCCCEEEECHH
RAGLSQADVLIDFTRPDATLNHLNVARELGTAVVIGTTGFTAEQKASFKTYGESIGVVWA
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHCHHHHHCCCCCEEEC
PNMSVGVNATFKLIEVAAKILAQGYDVEIIEAHHKHKIDAPSGTALKMGEIVAEAQGTKL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCCH
ADRAVYAREGETGPRELGTIGFATVRGGDIVGDHTVLFAGDGERIEITHRSNTRQSYAEG
HHHEEEECCCCCCCHHHCCEEEEEECCCCEECCCEEEEECCCCEEEEEECCCCHHHHHHH
AVRAAVYVAGKKGLYDMNDVLGL
HEEEEEEEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA