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The map label for this gene is intZ [H]

Identifier: 187929820

GI number: 187929820

Start: 2862478

End: 2863725

Strand: Reverse

Name: intZ [H]

Synonym: Rpic_2751

Alternate gene names: 187929820

Gene position: 2863725-2862478 (Counterclockwise)

Preceding gene: 187929821

Following gene: 187929819

Centisome position: 72.64

GC content: 63.54

Gene sequence:

>1248_bases
ATGCGCCACTTCAACTACAAGCTGACGCCCACCCGTATCAACAACGCTAAGCCCAAGGAACAGCCCTACAAGCTCACGGA
CGGCGGCGGCCTGTTTGTCCTGGTGCACCCGGGCGGCTCGAAGGCCTGGCGCTACCAATACATGCTCTCGGGCAAGCGCC
GATCGGTGCTGATCGGGAGCTATCCCGAAATCGGCGTGTCTGATGCGCGCGACCGGCACGCCGAATACAGGGCAATGGTC
GAGCAGGGCACTGATCCGGCCGAACACCGGCGCCAGGACAAGGCAGAGCGCAAGGCCAAGGAATCACTGCAGGAGGATGA
GGGGCTATTCAAGGCGTTCTCCCTCAAGTGGATCGATGAGCGCTTGGCTACGAAAACCGAGGGGTACCGCAGCCAGATCA
AGTCGCGCTTGGAACGTTTCGTGTGGCCGGTCATCGGCCGCAAGGCCTTAGAAGACGTGAAGCCGTCCCACCTGCTGGAG
ATCATCGAGGCCCGGCGCGCCACGCCAAACACCGCGGAGGGCGTACGGGTCATCATTCAGCAGATCTACAACTACGCCAT
CCAGAAGCTGCTTGTAGAGAGCAATCCGGCAGTTCCTCTGCGCGGCGTCATCACCGTGCCCAAGGCTGAGCACCATCGGC
ACCTCAGCGAATCGGAACTGGGCGCGTTCTGGCGCGCTCTCGGGCGCCAGGGCGCACACCCGGCTACCACCGCGGCGGCG
CGCCTGCTGGTCTACAGCATGTGCCGCAAGTCCGAGGTGCTGCGCGCGAAGTGGGCGGAGTTCGATCTCGACAAAGCCCA
GTGGGACATCCCTGCCGAGCGGATGAAGTCGCGCCGCCCACATCGTGTGTATCTGTCGCGCCAAGCCATTGAGTTGTTGG
AGATCATGCGCGCGATCAGCGGCGATGGGGTGTACGTCCTCCCCTCGGTGAAGATCGCCAGCGTGCCGTTGGCCGAGGCC
ACGCTGAACCACCTGTTCAAACGCCTGGACTTCGGCGTGCCCGAGTTTTCCCCGCACGGCACGCGTGGCACTGCGGCGAC
GCTACTGCGCGAGCACGGATTTAGCCGGGATGTGGTTGAGCTGCTACTTGCCCACACTGAGCGCAGCCAGACGGCGGCGA
GCTACCACCATCACGAACTGGAAGCGGAGCGGCGCAAGGCGCTGCAGTACTTGGCAGATGAGATCGATCGGCAGGCGGCC
ATATCGGCAGCCGGCAATGTGGTGAGTCTCAAGGGCCGGGCAGCATAA

Upstream 100 bases:

>100_bases
TCCAGAAAGATTGAGTACGATCCGGCGCTAAGTGAGTGTTGTACGGAGTATTTTGGGGGCGAAGCAATACTCAAAGTGCT
CACTTCTGAGGATCGCTGCC

Downstream 100 bases:

>100_bases
CGGTAACAGCCGCGCCTAGATCGGCCAATCGAAAACGGGTTCTCTCACCCGCTGGCGCTGCTCTCTTTTTCGAGGGACTT
TGCGTGAGGGCGCAAGGATG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MRHFNYKLTPTRINNAKPKEQPYKLTDGGGLFVLVHPGGSKAWRYQYMLSGKRRSVLIGSYPEIGVSDARDRHAEYRAMV
EQGTDPAEHRRQDKAERKAKESLQEDEGLFKAFSLKWIDERLATKTEGYRSQIKSRLERFVWPVIGRKALEDVKPSHLLE
IIEARRATPNTAEGVRVIIQQIYNYAIQKLLVESNPAVPLRGVITVPKAEHHRHLSESELGAFWRALGRQGAHPATTAAA
RLLVYSMCRKSEVLRAKWAEFDLDKAQWDIPAERMKSRRPHRVYLSRQAIELLEIMRAISGDGVYVLPSVKIASVPLAEA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRKALQYLADEIDRQAA
ISAAGNVVSLKGRAA

Sequences:

>Translated_415_residues
MRHFNYKLTPTRINNAKPKEQPYKLTDGGGLFVLVHPGGSKAWRYQYMLSGKRRSVLIGSYPEIGVSDARDRHAEYRAMV
EQGTDPAEHRRQDKAERKAKESLQEDEGLFKAFSLKWIDERLATKTEGYRSQIKSRLERFVWPVIGRKALEDVKPSHLLE
IIEARRATPNTAEGVRVIIQQIYNYAIQKLLVESNPAVPLRGVITVPKAEHHRHLSESELGAFWRALGRQGAHPATTAAA
RLLVYSMCRKSEVLRAKWAEFDLDKAQWDIPAERMKSRRPHRVYLSRQAIELLEIMRAISGDGVYVLPSVKIASVPLAEA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRKALQYLADEIDRQAA
ISAAGNVVSLKGRAA
>Mature_415_residues
MRHFNYKLTPTRINNAKPKEQPYKLTDGGGLFVLVHPGGSKAWRYQYMLSGKRRSVLIGSYPEIGVSDARDRHAEYRAMV
EQGTDPAEHRRQDKAERKAKESLQEDEGLFKAFSLKWIDERLATKTEGYRSQIKSRLERFVWPVIGRKALEDVKPSHLLE
IIEARRATPNTAEGVRVIIQQIYNYAIQKLLVESNPAVPLRGVITVPKAEHHRHLSESELGAFWRALGRQGAHPATTAAA
RLLVYSMCRKSEVLRAKWAEFDLDKAQWDIPAERMKSRRPHRVYLSRQAIELLEIMRAISGDGVYVLPSVKIASVPLAEA
TLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVELLLAHTERSQTAASYHHHELEAERRKALQYLADEIDRQAA
ISAAGNVVSLKGRAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=403, Percent_Identity=34.4913151364764, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1788974, Length=393, Percent_Identity=30.0254452926209, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788690, Length=395, Percent_Identity=27.5949367088608, Blast_Score=163, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47010; Mature: 47010

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00191 CYTOCHROME_B5_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFNYKLTPTRINNAKPKEQPYKLTDGGGLFVLVHPGGSKAWRYQYMLSGKRRSVLIGS
CCCCCCEECCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEHHEECCCCCEEEEEC
YPEIGVSDARDRHAEYRAMVEQGTDPAEHRRQDKAERKAKESLQEDEGLFKAFSLKWIDE
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLATKTEGYRSQIKSRLERFVWPVIGRKALEDVKPSHLLEIIEARRATPNTAEGVRVIIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QIYNYAIQKLLVESNPAVPLRGVITVPKAEHHRHLSESELGAFWRALGRQGAHPATTAAA
HHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
RLLVYSMCRKSEVLRAKWAEFDLDKAQWDIPAERMKSRRPHRVYLSRQAIELLEIMRAIS
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHC
GDGVYVLPSVKIASVPLAEATLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVE
CCCEEEECCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LLLAHTERSQTAASYHHHELEAERRKALQYLADEIDRQAAISAAGNVVSLKGRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MRHFNYKLTPTRINNAKPKEQPYKLTDGGGLFVLVHPGGSKAWRYQYMLSGKRRSVLIGS
CCCCCCEECCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEHHEECCCCCEEEEEC
YPEIGVSDARDRHAEYRAMVEQGTDPAEHRRQDKAERKAKESLQEDEGLFKAFSLKWIDE
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLATKTEGYRSQIKSRLERFVWPVIGRKALEDVKPSHLLEIIEARRATPNTAEGVRVIIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QIYNYAIQKLLVESNPAVPLRGVITVPKAEHHRHLSESELGAFWRALGRQGAHPATTAAA
HHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
RLLVYSMCRKSEVLRAKWAEFDLDKAQWDIPAERMKSRRPHRVYLSRQAIELLEIMRAIS
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHC
GDGVYVLPSVKIASVPLAEATLNHLFKRLDFGVPEFSPHGTRGTAATLLREHGFSRDVVE
CCCEEEECCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LLLAHTERSQTAASYHHHELEAERRKALQYLADEIDRQAAISAAGNVVSLKGRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]