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The map label for this gene is arcB [H]

Identifier: 187929794

GI number: 187929794

Start: 2837977

End: 2839872

Strand: Reverse

Name: arcB [H]

Synonym: Rpic_2724

Alternate gene names: 187929794

Gene position: 2839872-2837977 (Counterclockwise)

Preceding gene: 187929799

Following gene: 187929792

Centisome position: 72.03

GC content: 66.61

Gene sequence:

>1896_bases
GTGCGCCCGCGCGGTTCATGCTTGCGGCACAATCCGGTATCCAGTTTCTTCCCTACATCCCCCTTGAACGCCTCGCTGCG
CCTTTTTTTCGCCAAGTTCGGGCTTGCCAGCCGCGCGCCGCTTGAACTGGATGCCCGAGCCAAGCTGCTCGCCGCCGTGC
ATCGCGGGGCGCCCATGGGGATCGCCGCCTCGGTCGTCCTGCCTGCCTTGACGGTCGCCGCGTTCTGGGATGCCTCCAAC
CGGCCGGGGCTATTGGGCTGGTGCCTGATCATGCTGTGCCTGACGGCGTCGGGCCTGCGCTTCTATTTCGGCTATCGCTA
CGACCTGACCCGCATGACGCTGGCCGCGCACACCCGCAAGTGGTGGACGGGCATGCACGTCATGTCGGCGGTGGGCGGGG
TGGCGTGGGGCTGCTCGGCGGGGCTGTATCTGATGTCGCCGTCGCTGGAGTTCAGCAGCCTGCTGATGATCGTGATCATC
GGTGTGGCGGCGGCGGCGGTGTTGTCGCAAGCGCCGGTGCCGTCGAGCCTCCTGATCCTCGGAACGGGCATCCTGGCGCC
GCACTTTTTGCTGGCCGAGCAGGCGTTTCCGGGGCACGGGCTGTATTTGCGCGGCGTGCTGCTGTTCTTTGCGGCGCTGC
TGACCCGGCATGCCGTGAACATCCACAACACGCTGGTGCGCGAAATCCAGTTGGAGAACGAGAGCCGCCAGCTCGCGCGC
CGCTATCAGGATGAAAAGCAGCGCGCATTGTCGGCATCGGAAGAAAAATCGCGCTTCCTGGCCGCGGCCAGCCACGATTT
GCGTCAGCCGGTGCATGCAATTGTGCTGCTGGTGGAGGCGTTGCGGGCGCGCAATCAGTCGGAATCCTTGGCGCCATTGG
TGGAACAACTCGCCTCGGGCGCCGCGACCATCGACCTGCTGTTCCGCTCGCTGCTGGACCTGTCCAAGCTGGAGAGCCGC
AAGACCTCGCCGACACTGGAGCCGGTGGATCTGGGCGAGGTGATCACCGAGGTGGTCCAGCAATTCATGCCGGATGCCCG
CGCCAAGGGCCTGACGCTCGCGGCGCGCATTCCGCCGCTGCCGGTGTACGGGATGGCCGAGCCGGTGCTGCTGCGCCGGG
CGCTGTTCAACCTGCTGCAGAACGCGCTGCGCTACACCGAGCGCGGTGGCGTGATGGTGGCGCTGCGCGTGCGCCAGAAG
CATTTGCGGATCGAGGTGTGGGATACCGGTATCGGCATCGCGCCTGAGCATCAGAAAGACATTTTCTCGACCTACTACCA
GGTCGAAAACCCAGAACGCGATCCGAGCCAGGGCTTGGGTTTGGGCCTGTCGATCTACAAGGAATGCGTGCGTCTGCTGC
GCGGCACGTTCGGCGTGCGCTCGGTGCCGGGGCGCGGCTCGATGTTTTGGATGGCGCTGCGGCCGGTGCCCGCCGAGATC
AAGGCGCCGCTGGCCACGCAGCCGCGCGCCGAGCAAAAGCGCGCCGTGCTCGATCAGCCGCGATTCTCCGGCGTGGTACT
GGTCGTGGACGACGACCCGCAGATCCGCAAGGCCTGGCACGCGCTGCTCGAAGCGTGGGGCGTGGAAGTCCACAGTGCCG
CCGATGGCCGCTCAGCCGAGCAACTGCTGGCGCGCGGCATCCGTCCGCAGATCATCTTCTGCGACTTGCGCCTGCCCGGG
GAGGAAGACGGCCTGCAACTTCTCGAACGCTGGCAGGTTAGTCATCCGGATGCCCACGCCGTGCTGCTGACCGGCGATCG
CAATTCCGCCGCCCTGGCGCGTGCCGAAGAAGCCGGCTATCTGCTACTGGCCAAGCCCATGGACCCGAACATGCTGCGCG
TGCTGCTCAAGCGCTGGCTGCGCGGCCGCTCAGCCGAGCCGCAGGTGGCCTACTGA

Upstream 100 bases:

>100_bases
CAGGCGCCAAAATCCAGCAAAACGCACATTATATAAGGGATTGCCCCATCCCCGGCGCGCACGCGGATTGGTGTCGGGGT
GTTGCACAATCGTCCGAACG

Downstream 100 bases:

>100_bases
TACGGATGGGAATGTAAAACGGCGCCGTCGATGGCGGCGCCGGATTGAAGAGGCCAGACGCTCAGTTCAGGCCGCGCCCG
TCAGGCGAAAACGCTCCATG

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MRPRGSCLRHNPVSSFFPTSPLNASLRLFFAKFGLASRAPLELDARAKLLAAVHRGAPMGIAASVVLPALTVAAFWDASN
RPGLLGWCLIMLCLTASGLRFYFGYRYDLTRMTLAAHTRKWWTGMHVMSAVGGVAWGCSAGLYLMSPSLEFSSLLMIVII
GVAAAAVLSQAPVPSSLLILGTGILAPHFLLAEQAFPGHGLYLRGVLLFFAALLTRHAVNIHNTLVREIQLENESRQLAR
RYQDEKQRALSASEEKSRFLAAASHDLRQPVHAIVLLVEALRARNQSESLAPLVEQLASGAATIDLLFRSLLDLSKLESR
KTSPTLEPVDLGEVITEVVQQFMPDARAKGLTLAARIPPLPVYGMAEPVLLRRALFNLLQNALRYTERGGVMVALRVRQK
HLRIEVWDTGIGIAPEHQKDIFSTYYQVENPERDPSQGLGLGLSIYKECVRLLRGTFGVRSVPGRGSMFWMALRPVPAEI
KAPLATQPRAEQKRAVLDQPRFSGVVLVVDDDPQIRKAWHALLEAWGVEVHSAADGRSAEQLLARGIRPQIIFCDLRLPG
EEDGLQLLERWQVSHPDAHAVLLTGDRNSAALARAEEAGYLLLAKPMDPNMLRVLLKRWLRGRSAEPQVAY

Sequences:

>Translated_631_residues
MRPRGSCLRHNPVSSFFPTSPLNASLRLFFAKFGLASRAPLELDARAKLLAAVHRGAPMGIAASVVLPALTVAAFWDASN
RPGLLGWCLIMLCLTASGLRFYFGYRYDLTRMTLAAHTRKWWTGMHVMSAVGGVAWGCSAGLYLMSPSLEFSSLLMIVII
GVAAAAVLSQAPVPSSLLILGTGILAPHFLLAEQAFPGHGLYLRGVLLFFAALLTRHAVNIHNTLVREIQLENESRQLAR
RYQDEKQRALSASEEKSRFLAAASHDLRQPVHAIVLLVEALRARNQSESLAPLVEQLASGAATIDLLFRSLLDLSKLESR
KTSPTLEPVDLGEVITEVVQQFMPDARAKGLTLAARIPPLPVYGMAEPVLLRRALFNLLQNALRYTERGGVMVALRVRQK
HLRIEVWDTGIGIAPEHQKDIFSTYYQVENPERDPSQGLGLGLSIYKECVRLLRGTFGVRSVPGRGSMFWMALRPVPAEI
KAPLATQPRAEQKRAVLDQPRFSGVVLVVDDDPQIRKAWHALLEAWGVEVHSAADGRSAEQLLARGIRPQIIFCDLRLPG
EEDGLQLLERWQVSHPDAHAVLLTGDRNSAALARAEEAGYLLLAKPMDPNMLRVLLKRWLRGRSAEPQVAY
>Mature_631_residues
MRPRGSCLRHNPVSSFFPTSPLNASLRLFFAKFGLASRAPLELDARAKLLAAVHRGAPMGIAASVVLPALTVAAFWDASN
RPGLLGWCLIMLCLTASGLRFYFGYRYDLTRMTLAAHTRKWWTGMHVMSAVGGVAWGCSAGLYLMSPSLEFSSLLMIVII
GVAAAAVLSQAPVPSSLLILGTGILAPHFLLAEQAFPGHGLYLRGVLLFFAALLTRHAVNIHNTLVREIQLENESRQLAR
RYQDEKQRALSASEEKSRFLAAASHDLRQPVHAIVLLVEALRARNQSESLAPLVEQLASGAATIDLLFRSLLDLSKLESR
KTSPTLEPVDLGEVITEVVQQFMPDARAKGLTLAARIPPLPVYGMAEPVLLRRALFNLLQNALRYTERGGVMVALRVRQK
HLRIEVWDTGIGIAPEHQKDIFSTYYQVENPERDPSQGLGLGLSIYKECVRLLRGTFGVRSVPGRGSMFWMALRPVPAEI
KAPLATQPRAEQKRAVLDQPRFSGVVLVVDDDPQIRKAWHALLEAWGVEVHSAADGRSAEQLLARGIRPQIIFCDLRLPG
EEDGLQLLERWQVSHPDAHAVLLTGDRNSAALARAEEAGYLLLAKPMDPNMLRVLLKRWLRGRSAEPQVAY

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=327, Percent_Identity=29.3577981651376, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=29.0322580645161, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788713, Length=406, Percent_Identity=25.615763546798, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=28.936170212766, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=421, Percent_Identity=25.41567695962, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=29.957805907173, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=29.5546558704453, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=29.5964125560538, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.045643153527, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=300, Percent_Identity=27.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=28.9592760180996, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=25.7510729613734, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69580; Mature: 69580

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRGSCLRHNPVSSFFPTSPLNASLRLFFAKFGLASRAPLELDARAKLLAAVHRGAPMG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCC
IAASVVLPALTVAAFWDASNRPGLLGWCLIMLCLTASGLRFYFGYRYDLTRMTLAAHTRK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
WWTGMHVMSAVGGVAWGCSAGLYLMSPSLEFSSLLMIVIIGVAAAAVLSQAPVPSSLLIL
HHHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GTGILAPHFLLAEQAFPGHGLYLRGVLLFFAALLTRHAVNIHNTLVREIQLENESRQLAR
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RYQDEKQRALSASEEKSRFLAAASHDLRQPVHAIVLLVEALRARNQSESLAPLVEQLASG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
AATIDLLFRSLLDLSKLESRKTSPTLEPVDLGEVITEVVQQFMPDARAKGLTLAARIPPL
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEEECCCCC
PVYGMAEPVLLRRALFNLLQNALRYTERGGVMVALRVRQKHLRIEVWDTGIGIAPEHQKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHH
IFSTYYQVENPERDPSQGLGLGLSIYKECVRLLRGTFGVRSVPGRGSMFWMALRPVPAEI
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHH
KAPLATQPRAEQKRAVLDQPRFSGVVLVVDDDPQIRKAWHALLEAWGVEVHSAADGRSAE
CCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEECCCCCCHHH
QLLARGIRPQIIFCDLRLPGEEDGLQLLERWQVSHPDAHAVLLTGDRNSAALARAEEAGY
HHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCE
LLLAKPMDPNMLRVLLKRWLRGRSAEPQVAY
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRPRGSCLRHNPVSSFFPTSPLNASLRLFFAKFGLASRAPLELDARAKLLAAVHRGAPMG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCC
IAASVVLPALTVAAFWDASNRPGLLGWCLIMLCLTASGLRFYFGYRYDLTRMTLAAHTRK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
WWTGMHVMSAVGGVAWGCSAGLYLMSPSLEFSSLLMIVIIGVAAAAVLSQAPVPSSLLIL
HHHHHHHHHHHCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GTGILAPHFLLAEQAFPGHGLYLRGVLLFFAALLTRHAVNIHNTLVREIQLENESRQLAR
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RYQDEKQRALSASEEKSRFLAAASHDLRQPVHAIVLLVEALRARNQSESLAPLVEQLASG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
AATIDLLFRSLLDLSKLESRKTSPTLEPVDLGEVITEVVQQFMPDARAKGLTLAARIPPL
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEEECCCCC
PVYGMAEPVLLRRALFNLLQNALRYTERGGVMVALRVRQKHLRIEVWDTGIGIAPEHQKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHH
IFSTYYQVENPERDPSQGLGLGLSIYKECVRLLRGTFGVRSVPGRGSMFWMALRPVPAEI
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHH
KAPLATQPRAEQKRAVLDQPRFSGVVLVVDDDPQIRKAWHALLEAWGVEVHSAADGRSAE
CCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEECCCCCCHHH
QLLARGIRPQIIFCDLRLPGEEDGLQLLERWQVSHPDAHAVLLTGDRNSAALARAEEAGY
HHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCE
LLLAKPMDPNMLRVLLKRWLRGRSAEPQVAY
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]