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The map label for this gene is mmgC [H]

Identifier: 187929703

GI number: 187929703

Start: 2746223

End: 2747368

Strand: Reverse

Name: mmgC [H]

Synonym: Rpic_2632

Alternate gene names: 187929703

Gene position: 2747368-2746223 (Counterclockwise)

Preceding gene: 187929705

Following gene: 187929702

Centisome position: 69.68

GC content: 63.44

Gene sequence:

>1146_bases
ATGCTGCCACAGCTGTATCGCCACGCCTGGATGGACCACGAGATCGACGCTTTTCGCGAGCAGGTGCGTCGCTACGTTGC
CGCCGAATTCACTCCCCGGCTCGACGAATGGCGCCGCCAGGGCTACATCCCGCGCGAGGTCTGGCGTCCGTTCGGCGGGA
TGAGCTTTCTGCTGCCCGAGATGCCCGAGACCTATGGTGGTGCCGGCGCCAGCCTCGCCTACCAGCTGGTGGTGCAGGAC
GAACTGGCCAAGGCCGAGATGCCGGTCAATATCGCGGTGCACACCATCGCTTCGCATTACATCCTGGACTTTGGCACCGA
AGCGCAAAAGCAGCGCTGGCTGCCCAAGGTGACGAACGGCGAGATGCTGGCCGCCATCGCGATGACCGAGCCGGGCTGCG
GCTCGGATCTGAAGGCCATCTCCACCCGGGCCCGGCGCGACGGCGACTACTACGTGATCGACGGCGCCAAGACCTTCATC
ACCAACGGCTTCACCGGAAACCTGCTGATCGTCGCGGCGCGCACCAGTGGCGCGGGCAGCAAAGGGGTGTCGCTGTTCGT
ACTGGAGACCGAGAACCTGCCAGGCTTTCGTGTGGGCCGCCTGCTTGAAAAGATCGGCATGCAGGCCTCGGACACGGCGG
AGCTCTTCTTCGACAGCGTGCGCGTTCCAGCCGACCAACTGCTGGGGAGCGTTGAAGGCCAAGGCTTTGGGCAACTGATG
GGCGCGCTGCCCTACGAGCGCATGGTCATTGCAGTGCCGGCGGCGGCCGTCATCGACCGGGCGTTGGAGCTCACCATCGA
ATACACGAAGCAGCGCAAGATATTCGGTGCGCCTCTGTTCGACATGCAGACAACGCGCCAAAAGCTGGCCGAGATGGCGA
CCATCGCGCATGTGGTGCGCAGCTTCGTCAACGACTGTACACAGAGACTGCTGGACGGCACACTCGACAACGAGGCCGCC
TACATGGCCAAGTGGTGGTGCACCGAACAGCAGTGCCGCGTGGTGGACGAGTGTCTCCAATTGTTCGGCGGCTACGGCTA
CATGGCCGAGTATCCGATCGCGCGGATGTATGCCGCTTCGCGAGTGCAGAAGATCTACGGCGGCGCCAACGAGGTCCTGA
AAGACCTGGTTTCGAGGAAGCTGTGA

Upstream 100 bases:

>100_bases
CAATTACTACGATTGTCGCATCCCCAAAAACACTTCGGCAGTGGCGCTGTGCGGAACGCCCGGTGCGGGGTCAGAAGCCA
ACATACAAGGAGACATGCCC

Downstream 100 bases:

>100_bases
ACATGCCGCACACGCTGCAGTTGCCTCTGCACGGCGTCCGTGTGGTGGAGTTTGAGGGCATCGGTCCAGGCCCTCTGGCC
GCCAGGATGCTGGTCGACAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLPQLYRHAWMDHEIDAFREQVRRYVAAEFTPRLDEWRRQGYIPREVWRPFGGMSFLLPEMPETYGGAGASLAYQLVVQD
ELAKAEMPVNIAVHTIASHYILDFGTEAQKQRWLPKVTNGEMLAAIAMTEPGCGSDLKAISTRARRDGDYYVIDGAKTFI
TNGFTGNLLIVAARTSGAGSKGVSLFVLETENLPGFRVGRLLEKIGMQASDTAELFFDSVRVPADQLLGSVEGQGFGQLM
GALPYERMVIAVPAAAVIDRALELTIEYTKQRKIFGAPLFDMQTTRQKLAEMATIAHVVRSFVNDCTQRLLDGTLDNEAA
YMAKWWCTEQQCRVVDECLQLFGGYGYMAEYPIARMYAASRVQKIYGGANEVLKDLVSRKL

Sequences:

>Translated_381_residues
MLPQLYRHAWMDHEIDAFREQVRRYVAAEFTPRLDEWRRQGYIPREVWRPFGGMSFLLPEMPETYGGAGASLAYQLVVQD
ELAKAEMPVNIAVHTIASHYILDFGTEAQKQRWLPKVTNGEMLAAIAMTEPGCGSDLKAISTRARRDGDYYVIDGAKTFI
TNGFTGNLLIVAARTSGAGSKGVSLFVLETENLPGFRVGRLLEKIGMQASDTAELFFDSVRVPADQLLGSVEGQGFGQLM
GALPYERMVIAVPAAAVIDRALELTIEYTKQRKIFGAPLFDMQTTRQKLAEMATIAHVVRSFVNDCTQRLLDGTLDNEAA
YMAKWWCTEQQCRVVDECLQLFGGYGYMAEYPIARMYAASRVQKIYGGANEVLKDLVSRKL
>Mature_381_residues
MLPQLYRHAWMDHEIDAFREQVRRYVAAEFTPRLDEWRRQGYIPREVWRPFGGMSFLLPEMPETYGGAGASLAYQLVVQD
ELAKAEMPVNIAVHTIASHYILDFGTEAQKQRWLPKVTNGEMLAAIAMTEPGCGSDLKAISTRARRDGDYYVIDGAKTFI
TNGFTGNLLIVAARTSGAGSKGVSLFVLETENLPGFRVGRLLEKIGMQASDTAELFFDSVRVPADQLLGSVEGQGFGQLM
GALPYERMVIAVPAAAVIDRALELTIEYTKQRKIFGAPLFDMQTTRQKLAEMATIAHVVRSFVNDCTQRLLDGTLDNEAA
YMAKWWCTEQQCRVVDECLQLFGGYGYMAEYPIARMYAASRVQKIYGGANEVLKDLVSRKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=42.0911528150134, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=29.7082228116711, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI226958414, Length=352, Percent_Identity=31.25, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=31.283422459893, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4557233, Length=390, Percent_Identity=30.5128205128205, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=28.5714285714286, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=31.4814814814815, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4557231, Length=369, Percent_Identity=28.7262872628726, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI187960098, Length=369, Percent_Identity=28.7262872628726, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI76496475, Length=331, Percent_Identity=32.02416918429, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4557235, Length=331, Percent_Identity=32.02416918429, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=28.5333333333333, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7669494, Length=349, Percent_Identity=29.7994269340974, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI38505218, Length=387, Percent_Identity=27.1317829457364, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=29.0657439446367, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=29.0657439446367, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI218563752, Length=317, Percent_Identity=25.5520504731861, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081958, Length=369, Percent_Identity=28.1842818428184, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786223, Length=365, Percent_Identity=26.5753424657534, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87082384, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=30.5851063829787, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=31.9148936170213, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=29.2105263157895, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=28.6089238845144, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=30.1104972375691, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=28.125, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=28.4153005464481, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=27.2251308900524, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17569725, Length=360, Percent_Identity=27.2222222222222, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=343, Percent_Identity=29.7376093294461, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=253, Percent_Identity=33.596837944664, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=31.8840579710145, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=305, Percent_Identity=29.1803278688525, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=284, Percent_Identity=25.3521126760563, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=370, Percent_Identity=28.3783783783784, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=295, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=30.5483028720627, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=31.9783197831978, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=29.6495956873315, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24666513, Length=324, Percent_Identity=30.5555555555556, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=28.1081081081081, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281363737, Length=302, Percent_Identity=31.1258278145695, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=28.686327077748, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42570; Mature: 42570

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPQLYRHAWMDHEIDAFREQVRRYVAAEFTPRLDEWRRQGYIPREVWRPFGGMSFLLPE
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCCCEECCCC
MPETYGGAGASLAYQLVVQDELAKAEMPVNIAVHTIASHYILDFGTEAQKQRWLPKVTNG
CCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
EMLAAIAMTEPGCGSDLKAISTRARRDGDYYVIDGAKTFITNGFTGNLLIVAARTSGAGS
CEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCC
KGVSLFVLETENLPGFRVGRLLEKIGMQASDTAELFFDSVRVPADQLLGSVEGQGFGQLM
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHH
GALPYERMVIAVPAAAVIDRALELTIEYTKQRKIFGAPLFDMQTTRQKLAEMATIAHVVR
HCCCHHHEEEECCHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFVNDCTQRLLDGTLDNEAAYMAKWWCTEQQCRVVDECLQLFGGYGYMAEYPIARMYAAS
HHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHH
RVQKIYGGANEVLKDLVSRKL
HHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLPQLYRHAWMDHEIDAFREQVRRYVAAEFTPRLDEWRRQGYIPREVWRPFGGMSFLLPE
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCCCEECCCC
MPETYGGAGASLAYQLVVQDELAKAEMPVNIAVHTIASHYILDFGTEAQKQRWLPKVTNG
CCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
EMLAAIAMTEPGCGSDLKAISTRARRDGDYYVIDGAKTFITNGFTGNLLIVAARTSGAGS
CEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCC
KGVSLFVLETENLPGFRVGRLLEKIGMQASDTAELFFDSVRVPADQLLGSVEGQGFGQLM
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHH
GALPYERMVIAVPAAAVIDRALELTIEYTKQRKIFGAPLFDMQTTRQKLAEMATIAHVVR
HCCCHHHEEEECCHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SFVNDCTQRLLDGTLDNEAAYMAKWWCTEQQCRVVDECLQLFGGYGYMAEYPIARMYAAS
HHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHH
RVQKIYGGANEVLKDLVSRKL
HHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]