Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 187929460

GI number: 187929460

Start: 2475714

End: 2476694

Strand: Reverse

Name: qor [H]

Synonym: Rpic_2381

Alternate gene names: 187929460

Gene position: 2476694-2475714 (Counterclockwise)

Preceding gene: 187929461

Following gene: 187929454

Centisome position: 62.82

GC content: 64.53

Gene sequence:

>981_bases
ATGACACAAGCGAAAGCCATCCGCATCTTTGAAACCGGCGGCCCCGAAGTGATGCAGTACGTCGATGTCGACGTGCCCGC
GCCCGGCCCCGGCGAGGCCACCATCAAGCAGCACGCCATCGGCCTGAACTACATCGACGTCTATTTCCGCACCGGGCTGT
ATCCCCAGCCCCTGCCTGGCGGCATCGGCATGGAAGCCGCGGGTGTGGTCGAAGCCGTGGGCCAGGGCGTGACGCACGTC
AAGCCGGGCGACCGCGTGGCCTACGCCGGCCGTCCGACCGGCGCCTACGCTGCGTTGCGCACGATGCCGGCCGACATTCT
CGTGCGCCTGCCCGATGCGATCGACTTTGAAACCGGCGCAGCGATGATGCTGCAGGGCATGACCGCGCAATACCTGATCC
GAGACAGCTATCGCGTGCAGCCCGGCGATACGGTGCTGTTTCACGCAGCCGCTGGCGGTGTGGGGTTGATTGCGTGCCAG
TGGCTCAAGGCGCTCGGCGCCACGGTGATTGGCACCGTTGGCAGCGATGCCAAGGCTGAACTTGCCTGCGCGCACGGTTG
CGACCACACCATCGTCTACACCCGTGAGAACTTTACCGAACGCGTGCGCGAAATCACTGGCGGCAAGGGCGTGCCGGTGG
TCTACGACGGCATTGGCAAAGACACGTTCACGGGCTCGCTGGATTGCCTCGCACCGCGCGGGATGATGGTCACCTACGGC
AACGCATCTGGCCCAGTGCCACCGGTTGACCTCAGCGTGCTGAGCGCAAAAGGCTCGCTCAAGATCACGCGCCCGACGCT
GATGACTTACACGGCACGGCGCGAGCTGCTGGAACCGATGGCGGCAGAGTTGTTTGATGTGGTGAGCAGCGGCAAGGTCA
AGATCGAGATTCACCAGCGCTACGATCTGCAGAACGCGGCGCAGGCGCACCGCGATCTGGAAGCGCGCAAGACGACCGGG
TCGACGATCCTCTTGCCATAA

Upstream 100 bases:

>100_bases
GCGACGTCCACAACATCCCCTGCGCCACCAACCTCGCAACCGCCGACCTGGTGATGTCTGCCTTGCAACGGGTGGCGCCC
GATCCGAAGGAGATCCACGC

Downstream 100 bases:

>100_bases
GTCGAGGCGTTACCGCCCGGAGGGCTTCACACGCCGGGCGGCAGCAAAGCGCGCATCCTCGCGCACGCGGTCGGGCAGGC
CGCGCAGCAGCATGTGCAGC

Product: alcohol dehydrogenase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTQAKAIRIFETGGPEVMQYVDVDVPAPGPGEATIKQHAIGLNYIDVYFRTGLYPQPLPGGIGMEAAGVVEAVGQGVTHV
KPGDRVAYAGRPTGAYAALRTMPADILVRLPDAIDFETGAAMMLQGMTAQYLIRDSYRVQPGDTVLFHAAAGGVGLIACQ
WLKALGATVIGTVGSDAKAELACAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFTGSLDCLAPRGMMVTYG
NASGPVPPVDLSVLSAKGSLKITRPTLMTYTARRELLEPMAAELFDVVSSGKVKIEIHQRYDLQNAAQAHRDLEARKTTG
STILLP

Sequences:

>Translated_326_residues
MTQAKAIRIFETGGPEVMQYVDVDVPAPGPGEATIKQHAIGLNYIDVYFRTGLYPQPLPGGIGMEAAGVVEAVGQGVTHV
KPGDRVAYAGRPTGAYAALRTMPADILVRLPDAIDFETGAAMMLQGMTAQYLIRDSYRVQPGDTVLFHAAAGGVGLIACQ
WLKALGATVIGTVGSDAKAELACAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFTGSLDCLAPRGMMVTYG
NASGPVPPVDLSVLSAKGSLKITRPTLMTYTARRELLEPMAAELFDVVSSGKVKIEIHQRYDLQNAAQAHRDLEARKTTG
STILLP
>Mature_325_residues
TQAKAIRIFETGGPEVMQYVDVDVPAPGPGEATIKQHAIGLNYIDVYFRTGLYPQPLPGGIGMEAAGVVEAVGQGVTHVK
PGDRVAYAGRPTGAYAALRTMPADILVRLPDAIDFETGAAMMLQGMTAQYLIRDSYRVQPGDTVLFHAAAGGVGLIACQW
LKALGATVIGTVGSDAKAELACAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFTGSLDCLAPRGMMVTYGN
ASGPVPPVDLSVLSAKGSLKITRPTLMTYTARRELLEPMAAELFDVVSSGKVKIEIHQRYDLQNAAQAHRDLEARKTTGS
TILLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=32.2085889570552, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=32.2085889570552, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=32.5878594249201, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI194239676, Length=325, Percent_Identity=29.2307692307692, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=31.0975609756098, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=31.0975609756098, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24308257, Length=345, Percent_Identity=24.9275362318841, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI28557745, Length=239, Percent_Identity=31.7991631799163, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=28.042328042328, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41872631, Length=224, Percent_Identity=29.9107142857143, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI67078404, Length=235, Percent_Identity=28.0851063829787, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI67078406, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=326, Percent_Identity=50.3067484662577, Blast_Score=333, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17507255, Length=243, Percent_Identity=29.2181069958848, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17556000, Length=252, Percent_Identity=29.7619047619048, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=326, Percent_Identity=39.5705521472393, Blast_Score=221, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34631; Mature: 34500

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAKAIRIFETGGPEVMQYVDVDVPAPGPGEATIKQHAIGLNYIDVYFRTGLYPQPLPG
CCCCEEEEEEECCCHHEEEEEECCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCC
GIGMEAAGVVEAVGQGVTHVKPGDRVAYAGRPTGAYAALRTMPADILVRLPDAIDFETGA
CCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHCCHHHEEECCCCCCCCCCH
AMMLQGMTAQYLIRDSYRVQPGDTVLFHAAAGGVGLIACQWLKALGATVIGTVGSDAKAE
HHHHHCCCCEEEEECCEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCE
LACAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFTGSLDCLAPRGMMVTYG
EEEECCCCCEEEEECHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEC
NASGPVPPVDLSVLSAKGSLKITRPTLMTYTARRELLEPMAAELFDVVSSGKVKIEIHQR
CCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
YDLQNAAQAHRDLEARKTTGSTILLP
CCHHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
TQAKAIRIFETGGPEVMQYVDVDVPAPGPGEATIKQHAIGLNYIDVYFRTGLYPQPLPG
CCCEEEEEEECCCHHEEEEEECCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCC
GIGMEAAGVVEAVGQGVTHVKPGDRVAYAGRPTGAYAALRTMPADILVRLPDAIDFETGA
CCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHCCHHHEEECCCCCCCCCCH
AMMLQGMTAQYLIRDSYRVQPGDTVLFHAAAGGVGLIACQWLKALGATVIGTVGSDAKAE
HHHHHCCCCEEEEECCEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCE
LACAHGCDHTIVYTRENFTERVREITGGKGVPVVYDGIGKDTFTGSLDCLAPRGMMVTYG
EEEECCCCCEEEEECHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEC
NASGPVPPVDLSVLSAKGSLKITRPTLMTYTARRELLEPMAAELFDVVSSGKVKIEIHQR
CCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
YDLQNAAQAHRDLEARKTTGSTILLP
CCHHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]