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The map label for this gene is yggV [C]

Identifier: 187929360

GI number: 187929360

Start: 2401095

End: 2401700

Strand: Direct

Name: yggV [C]

Synonym: Rpic_2281

Alternate gene names: 187929360

Gene position: 2401095-2401700 (Clockwise)

Preceding gene: 187929359

Following gene: 187929361

Centisome position: 60.9

GC content: 65.18

Gene sequence:

>606_bases
ATGCGCAAGATCGTTCTCGCATCAAACAACGCCGGCAAGCTGGCCGAGTTCAACACGCTGCTGGGCACCCTCGGGTTCGA
CGTGACGCCGCAAGGCGCGCTCGGCATTCCCGAGGCGGAAGAGCCCTATGCGACGTTCGTTGAAAACGCGCTCACCAAGG
CGCGCCACGCGAGCCGTGCGTCGGGCCTGCCTGCGTTGGCAGACGACTCCGGCATCTGCGTGCATGCGTTGGGCGGCGCG
CCGGGCGTGTATTCCGCGCGCTATGCGCAACTGGTGGGCGAGCCCAAATCGGACGCCGCCAACAACGCCCGCCTCGTCCG
CGAACTGGTCGGCAAAGCGGATCGCGGAGCACACTATGTTTGCGTGCTTGTCTACGTGCGCCATGCCGATGACCCGCAGC
CGATCATTGCCGAAGGCAACTGGTTTGGCGAGGTGATCGACACACCGCGCGGCGACGGCGGCTTCGGCTACGACCCACAC
TTCCTGCTGCCCAATCTCGGCAAGACCGCCGCCGAACTGACCAAGGCCGAGAAGAACAGCGTGAGCCATCGTGCACAAGC
CCTCGCGCAGCTCGTCGAACGGCTGCGCACCTTTGAAAACGCCTGA

Upstream 100 bases:

>100_bases
CGCGTGCCGAAATGGATGCAATGCTGGGCTTGGCCGATCAAGGCATCCGCACGCTGATCAGCCTGCAGAAGCAGGCGCTG
GGCCTGTGATCGACACGGCC

Downstream 100 bases:

>100_bases
CGTTCCGATGATCCCGATTTACCCCGCCGGCGCAGCCAAGACGCCTGCCGCGACTGCCGCTGAGACCGGTGACAAGGTCA
CCTCCGTCTTCCTGCAGCCG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRKIVLASNNAGKLAEFNTLLGTLGFDVTPQGALGIPEAEEPYATFVENALTKARHASRASGLPALADDSGICVHALGGA
PGVYSARYAQLVGEPKSDAANNARLVRELVGKADRGAHYVCVLVYVRHADDPQPIIAEGNWFGEVIDTPRGDGGFGYDPH
FLLPNLGKTAAELTKAEKNSVSHRAQALAQLVERLRTFENA

Sequences:

>Translated_201_residues
MRKIVLASNNAGKLAEFNTLLGTLGFDVTPQGALGIPEAEEPYATFVENALTKARHASRASGLPALADDSGICVHALGGA
PGVYSARYAQLVGEPKSDAANNARLVRELVGKADRGAHYVCVLVYVRHADDPQPIIAEGNWFGEVIDTPRGDGGFGYDPH
FLLPNLGKTAAELTKAEKNSVSHRAQALAQLVERLRTFENA
>Mature_201_residues
MRKIVLASNNAGKLAEFNTLLGTLGFDVTPQGALGIPEAEEPYATFVENALTKARHASRASGLPALADDSGICVHALGGA
PGVYSARYAQLVGEPKSDAANNARLVRELVGKADRGAHYVCVLVYVRHADDPQPIIAEGNWFGEVIDTPRGDGGFGYDPH
FLLPNLGKTAAELTKAEKNSVSHRAQALAQLVERLRTFENA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=194, Percent_Identity=33.5051546391753, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31657144, Length=147, Percent_Identity=34.6938775510204, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=51.010101010101, Blast_Score=206, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17556833, Length=200, Percent_Identity=31.5, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920712, Length=190, Percent_Identity=33.6842105263158, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21375; Mature: 21375

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVLASNNAGKLAEFNTLLGTLGFDVTPQGALGIPEAEEPYATFVENALTKARHASRA
CCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SGLPALADDSGICVHALGGAPGVYSARYAQLVGEPKSDAANNARLVRELVGKADRGAHYV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEE
CVLVYVRHADDPQPIIAEGNWFGEVIDTPRGDGGFGYDPHFLLPNLGKTAAELTKAEKNS
EEEEEECCCCCCCCEEECCCEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSHRAQALAQLVERLRTFENA
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIVLASNNAGKLAEFNTLLGTLGFDVTPQGALGIPEAEEPYATFVENALTKARHASRA
CCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SGLPALADDSGICVHALGGAPGVYSARYAQLVGEPKSDAANNARLVRELVGKADRGAHYV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEE
CVLVYVRHADDPQPIIAEGNWFGEVIDTPRGDGGFGYDPHFLLPNLGKTAAELTKAEKNS
EEEEEECCCCCCCCEEECCCEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSHRAQALAQLVERLRTFENA
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]