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The map label for this gene is iorA [H]

Identifier: 187929170

GI number: 187929170

Start: 2202825

End: 2203292

Strand: Reverse

Name: iorA [H]

Synonym: Rpic_2091

Alternate gene names: 187929170

Gene position: 2203292-2202825 (Counterclockwise)

Preceding gene: 187929171

Following gene: 187929169

Centisome position: 55.88

GC content: 67.74

Gene sequence:

>468_bases
ATGGAACTGGACGTCAACCACAAGCCGGTCAGCGTTGATTGCGACCCGGCCACGCCGCTACTGTGGGTGCTGCGTGATCA
CCTGAACCTGACCGGTACGAAGTTCGGCTGCGGCGTCGCGGCGTGCGGCGCATGCACCGTACACGTGGACGGCGCGGCCG
TGCGGTCGTGCGTGCTGCCGGTGGCGGCTGTGGCCGGCAAGCACATCACCACCATCGAAGGACTTGCCGGCGGCGGGGGC
AAACGCCACGCGCTGCAGCAAGCCTGGATTGACGAGCAGGTGCCCCAGTGCGGCTACTGCCAGTCCGGCATGCTCATGGC
CGCGGCGGACTTGCTGGCCCAACACCCTGACCCGACGGATGCCGACATCGACGCGGCCATGACCAACATCTGCCGTTGTG
GCACATATCCGCGCATGCGCGCCGCTATCAAGCGCGCTGCCAAGGCGTTGCGGGAGGGCCGCGCATGA

Upstream 100 bases:

>100_bases
ATGTTGCCATGTCGAGGTGGACCACTATTGCTGACCTCAGCCGTTTGAACGTACGCTTGGCCAGCAAAAAAGAATCACAA
CACAAGGAGACCACCGCCCC

Downstream 100 bases:

>100_bases
ACGCGAAGACTACAAAACCGCGCAGCGGACGCCGCCGTTTCCTGCTCGGCGCACTCGGCATTGGTGGCGCACTGGTAGTC
GGTTGGGGTGTGATGCCGCC

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MELDVNHKPVSVDCDPATPLLWVLRDHLNLTGTKFGCGVAACGACTVHVDGAAVRSCVLPVAAVAGKHITTIEGLAGGGG
KRHALQQAWIDEQVPQCGYCQSGMLMAAADLLAQHPDPTDADIDAAMTNICRCGTYPRMRAAIKRAAKALREGRA

Sequences:

>Translated_155_residues
MELDVNHKPVSVDCDPATPLLWVLRDHLNLTGTKFGCGVAACGACTVHVDGAAVRSCVLPVAAVAGKHITTIEGLAGGGG
KRHALQQAWIDEQVPQCGYCQSGMLMAAADLLAQHPDPTDADIDAAMTNICRCGTYPRMRAAIKRAAKALREGRA
>Mature_155_residues
MELDVNHKPVSVDCDPATPLLWVLRDHLNLTGTKFGCGVAACGACTVHVDGAAVRSCVLPVAAVAGKHITTIEGLAGGGG
KRHALQQAWIDEQVPQCGYCQSGMLMAAADLLAQHPDPTDADIDAAMTNICRCGTYPRMRAAIKRAAKALREGRA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=140, Percent_Identity=35, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=33.5526315789474, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=37.7245508982036, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1789232, Length=139, Percent_Identity=40.2877697841727, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=143, Percent_Identity=40.5594405594406, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=146, Percent_Identity=36.3013698630137, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=145, Percent_Identity=37.2413793103448, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17737937, Length=158, Percent_Identity=34.8101265822785, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=32.7160493827161, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=32.7160493827161, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=33.5526315789474, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647193, Length=136, Percent_Identity=33.0882352941176, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=32.258064516129, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16260; Mature: 16260

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELDVNHKPVSVDCDPATPLLWVLRDHLNLTGTKFGCGVAACGACTVHVDGAAVRSCVLP
CCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECHHHHHHHHHH
VAAVAGKHITTIEGLAGGGGKRHALQQAWIDEQVPQCGYCQSGMLMAAADLLAQHPDPTD
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
ADIDAAMTNICRCGTYPRMRAAIKRAAKALREGRA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELDVNHKPVSVDCDPATPLLWVLRDHLNLTGTKFGCGVAACGACTVHVDGAAVRSCVLP
CCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECHHHHHHHHHH
VAAVAGKHITTIEGLAGGGGKRHALQQAWIDEQVPQCGYCQSGMLMAAADLLAQHPDPTD
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
ADIDAAMTNICRCGTYPRMRAAIKRAAKALREGRA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]