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The map label for this gene is intB [H]

Identifier: 187929151

GI number: 187929151

Start: 2181268

End: 2182491

Strand: Reverse

Name: intB [H]

Synonym: Rpic_2072

Alternate gene names: 187929151

Gene position: 2182491-2181268 (Counterclockwise)

Preceding gene: 187929152

Following gene: 187929150

Centisome position: 55.36

GC content: 64.46

Gene sequence:

>1224_bases
ATGGCTCTCACAGACACGGCGGTCCGCAACGCCCGGCCGGCCGAAAAGCCTATCAAGCTGTTTGATGGCGGCGGCTTGTT
TCTCCACATCACGCCCGGCGGGCAGCGCTACTGGCGGCTGAAGTATCGGTTCGCGGGCAAAGAGAAGCTGCTGGCCCTTG
GCGTGTACCCTGAAGTCGGCCTGAAAGAGGCGAGGGACCGGCGCGAGGAAGCCAAACGGCTGCTGGGCGAGGGGGTTGAC
CCGTCAGTCGAACGCAAGGTGCGGAAGGTGGCGACGGTCGAGCGGGCGGCAAACAGTTTTGAGGCTGTGGCCCGCGAGTG
GCACACCAAGTACGCGCCCGGGTGGTCCAAGAGCAACGCCGACAAGGTGATCGCCCGCCTGCAGAACGACGTATTCCCCT
GGCTCGGCGGCCGGCCGATCGCTGAGCTGAAGGCGCCCGATCTGCTGGCCGTGTGTCGCCGCGTCGAGTCTCGTGGCGCT
CTGGATACTGCACACCGAGTGCTGCAGACCTGCGGCCAGATCTTCCGCTACGCTGTCGCCACTGGGCGGGCAGAGCGCGA
TCCGTCGGGTGACCTGCGGGGCGCGTTGCCGCCGGCCAAGGGGAAGCACTACGCCGCGCCGACCGACCCCAAAGAGGTGG
CCGGCTTGCTGCGTGTGTTTGACGGCTTCACCGGAACATTCGTTGTGAAGTGCGCGCTGCTGCTGGCCCCAATGCTCTTC
GTTCGACCAGGTGAACTGCGGGCCGCGGAATGGGCAGACATCGATCTGGATGCAGGCGAATGGCGTTTCGTGTCATCCAA
GCGGGACGTGGCTCACATCGTGCCGCTATCCACCCAGGCCGTCGCAATCCTGCGTGATCTGCACGCGTTGACCGGCCACG
GGCACTACGTCTTCCCCGGTGCCAGAGACAAGAAAAAACCCATGTCGGAAGCTGCCATTAACGCGGCTCTCAAGCGCATG
GGTATCGATACGCAGAAGGAGTTCACCGGCCACGGCGTGCGCCCCATTGCGCGCACCATCCTGCGTGAGGTGCTGGGTTT
CGAGGCCGAGGTAATCGAGCTGCAACTAGCGCACAGGAAGAAAGACCCAAACGGCGCGGCATATGACCGTGTGGCCTTCC
TGGCTGTGCGCAAGCAGATGATGCAGGCGTGGGCGGATTACCTGGATCGCTTGAAGACTGGGGCAGCCGTAGTGCCAATG
CCTACGTCACGGACGGCCGCGTGA

Upstream 100 bases:

>100_bases
TTTCATTCCGTCAATGTCCGATAAGGTGCATTGACAGCCGGGGGTACGCGGGGGTATTTCTGGGGGTAGATGTGATACCC
CTGTGTGGAGGTACCCCCAA

Downstream 100 bases:

>100_bases
GAGGGGGCGGAGGGCTGATAGATGACAAAGAAAAAGGTCGCGGCTCGCCCCGCAACCCTCAAGCTGACCCCTCAAACGAT
TCTCGGCAAAGATGGGGCTT

Product: integrase family protein

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MALTDTAVRNARPAEKPIKLFDGGGLFLHITPGGQRYWRLKYRFAGKEKLLALGVYPEVGLKEARDRREEAKRLLGEGVD
PSVERKVRKVATVERAANSFEAVAREWHTKYAPGWSKSNADKVIARLQNDVFPWLGGRPIAELKAPDLLAVCRRVESRGA
LDTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRVFDGFTGTFVVKCALLLAPMLF
VRPGELRAAEWADIDLDAGEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGHYVFPGARDKKKPMSEAAINAALKRM
GIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDRLKTGAAVVPM
PTSRTAA

Sequences:

>Translated_407_residues
MALTDTAVRNARPAEKPIKLFDGGGLFLHITPGGQRYWRLKYRFAGKEKLLALGVYPEVGLKEARDRREEAKRLLGEGVD
PSVERKVRKVATVERAANSFEAVAREWHTKYAPGWSKSNADKVIARLQNDVFPWLGGRPIAELKAPDLLAVCRRVESRGA
LDTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRVFDGFTGTFVVKCALLLAPMLF
VRPGELRAAEWADIDLDAGEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGHYVFPGARDKKKPMSEAAINAALKRM
GIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDRLKTGAAVVPM
PTSRTAA
>Mature_406_residues
ALTDTAVRNARPAEKPIKLFDGGGLFLHITPGGQRYWRLKYRFAGKEKLLALGVYPEVGLKEARDRREEAKRLLGEGVDP
SVERKVRKVATVERAANSFEAVAREWHTKYAPGWSKSNADKVIARLQNDVFPWLGGRPIAELKAPDLLAVCRRVESRGAL
DTAHRVLQTCGQIFRYAVATGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRVFDGFTGTFVVKCALLLAPMLFV
RPGELRAAEWADIDLDAGEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGHYVFPGARDKKKPMSEAAINAALKRMG
IDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRKKDPNGAAYDRVAFLAVRKQMMQAWADYLDRLKTGAAVVPMP
TSRTAA

Specific function: Unknown

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788690, Length=394, Percent_Identity=34.2639593908629, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI145693166, Length=397, Percent_Identity=36.272040302267, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1788974, Length=400, Percent_Identity=32.75, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44949; Mature: 44818

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTDTAVRNARPAEKPIKLFDGGGLFLHITPGGQRYWRLKYRFAGKEKLLALGVYPEVG
CCCCCHHHHCCCCCCCCCEEEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCC
LKEARDRREEAKRLLGEGVDPSVERKVRKVATVERAANSFEAVAREWHTKYAPGWSKSNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DKVIARLQNDVFPWLGGRPIAELKAPDLLAVCRRVESRGALDTAHRVLQTCGQIFRYAVA
HHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRVFDGFTGTFVVKCALLLAPMLF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VRPGELRAAEWADIDLDAGEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGHYVFPG
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEECCC
ARDKKKPMSEAAINAALKRMGIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRK
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
KDPNGAAYDRVAFLAVRKQMMQAWADYLDRLKTGAAVVPMPTSRTAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
>Mature Secondary Structure 
ALTDTAVRNARPAEKPIKLFDGGGLFLHITPGGQRYWRLKYRFAGKEKLLALGVYPEVG
CCCCHHHHCCCCCCCCCEEEECCEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCC
LKEARDRREEAKRLLGEGVDPSVERKVRKVATVERAANSFEAVAREWHTKYAPGWSKSNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DKVIARLQNDVFPWLGGRPIAELKAPDLLAVCRRVESRGALDTAHRVLQTCGQIFRYAVA
HHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TGRAERDPSGDLRGALPPAKGKHYAAPTDPKEVAGLLRVFDGFTGTFVVKCALLLAPMLF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VRPGELRAAEWADIDLDAGEWRFVSSKRDVAHIVPLSTQAVAILRDLHALTGHGHYVFPG
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEECCC
ARDKKKPMSEAAINAALKRMGIDTQKEFTGHGVRPIARTILREVLGFEAEVIELQLAHRK
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
KDPNGAAYDRVAFLAVRKQMMQAWADYLDRLKTGAAVVPMPTSRTAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]